Isolation, Chemical, and Biotransformation Routes of Labdane-type Diterpenes

The isolation, chemical and biotransformation routes of labdane-type diterpenes are discussed. These compounds can be biomanipulated to produce important synthetic intermediates.

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Bibliographic Details
Published in:	Chemical reviews Vol. 111; no. 8; pp. 4418 - 4452
Main Authors:	Frija, Luís M. T, Frade, Raquel F. M, Afonso, Carlos A. M
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 10-08-2011
Subjects:	Biotransformation Carboxylic Acids - chemistry Carboxylic Acids - pharmacokinetics Chemical compounds Diterpenes - chemistry Diterpenes - isolation & purification Diterpenes - pharmacokinetics Diterpenes, Abietane - chemistry Diterpenes, Abietane - isolation & purification Diterpenes, Abietane - pharmacokinetics Furans - chemistry Furans - pharmacokinetics Naphthalenes - chemistry Naphthalenes - pharmacokinetics Organic chemistry Pharmaceutical sciences Terpenes - chemistry Terpenes - pharmacokinetics Tetrahydronaphthalenes - chemistry Tetrahydronaphthalenes - pharmacokinetics
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Description
Summary:	The isolation, chemical and biotransformation routes of labdane-type diterpenes are discussed. These compounds can be biomanipulated to produce important synthetic intermediates.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-3 ObjectType-Review-1
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr100258k