Optimization of a Microfluidic Mixer for Studying Protein Folding Kinetics

We have applied an optimization method in conjunction with numerical simulations to minimize the mixing time of a microfluidic mixer developed for protein folding studies. The optimization method uses a semideterministic algorithm to find the global minimum of the mixing time by varying the mixer ge...

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Bibliographic Details
Published in:	Analytical chemistry (Washington) Vol. 78; no. 13; pp. 4299 - 4306
Main Authors:	Hertzog, David E, Ivorra, Benjamin, Mohammadi, Bijan, Bakajin, Olgica, Santiago, Juan G
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 01-07-2006
Subjects:	Algorithms Analytical chemistry Chemistry Exact sciences and technology Fluid dynamics Kinetics Mathematical models Microfluidics - instrumentation Optimization Protein Folding Simulation Performance evaluation Improvement Sensitivity Dyes Numerical simulation Review Algorithm Continuous flow method Microfluidics Optimization Protein
Online Access:	Get full text
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