Rapid Access to 2,2-Disubstituted Indolines via Dearomative Indolic-Claisen Rearrangement: Concise, Enantioselective Total Synthesis of (+)-Hinckdentine A
The construction of 2,2-disubstituted indolines has long presented a synthetic challenge without any general solutions. Herein, we report a robust protocol for the dearomative Meerwein–Eschenmoser–Claisen rearrangement of 3-indolyl alcohols that provides efficient access to 2-substituted and 2,2-dis...
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| Published in: | Journal of the American Chemical Society Vol. 145; no. 27; pp. 14831 - 14838 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
American Chemical Society
12-07-2023
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| Online Access: | Get full text |
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