In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis

• Published in: Antimicrobial Agents and Chemotherapy Vol. 17; no. 6; pp. 922 - 928
• Main Authors: Van den Bossche, H, Willemsens, G, Cools, W, Cornelissen, F, Lauwers, W F, van Cutsem, J M
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01-06-1980
• Subjects: Animals; Antifungal Agents; Antifungal Agents - pharmacology; Candida albicans; Candida albicans - drug effects; Candida albicans - growth & development; Candida albicans - metabolism; Cell Membrane - drug effects; Cholesterol - metabolism; Cholesterol - physiology; Culture Media; Dose-Response Relationship, Drug; Ergosterol; Ergosterol - biosynthesis; Female; Imidazoles; Imidazoles - pharmacology; Ketoconazole; Lanosterol - metabolism; Lanosterol - physiology; Piperazines; Piperazines - pharmacology; Rats; Research Article; Sterols - biosynthesis; Sterols - isolation & purification; Time Factors
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.17.6.922

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