Synthesis of Ring-Fused 1‑Benzazepines via [1,5]-Hydride Shift/7-Endo Cyclization Sequences
Synthesis of 1-benzazepines has been achieved via a [1,5]-hydride shift/7-endo cyclization sequence. The focus of this research is a direct transformation of 2-(aryl)cyclopropane 1,1-diester derivatives into 1-benzazepines using a cyclopropane moiety as the hydride acceptor in internal redox reacti...
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| Published in: | Organic letters Vol. 19; no. 6; pp. 1334 - 1337 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
American Chemical Society
17-03-2017
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| Online Access: | Get full text |
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| Summary: | Synthesis of 1-benzazepines has been achieved via a [1,5]-hydride shift/7-endo cyclization sequence. The focus of this research is a direct transformation of 2-(aryl)cyclopropane 1,1-diester derivatives into 1-benzazepines using a cyclopropane moiety as the hydride acceptor in internal redox reactions. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1523-7060 1523-7052 |
| DOI: | 10.1021/acs.orglett.7b00184 |