A Rare Prostaglandin from the Soft Coral Sarcophyton crassocaule of the Indian Ocean

• Published in: Journal of natural products (Washington, D.C.) Vol. 63; no. 10; pp. 1425 - 1426
• Main Authors: Anjaneyulu, A. S. R, Krishna Murthy, M. V. R, Gowri, P. Mangala, Venugopal, M. J. R. V, Laatsch, Hartmut
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01-10-2000; Glendale, AZ American Society of Pharmacognosy
• Subjects: Alcyonaria; Analytical, structural and metabolic biochemistry; Animals; Biological and medical sciences; Cnidaria - chemistry; Fundamental and applied biological sciences. Psychology; Indian Ocean; Intermediary metabolites. Miscellaneous; Marine; methyl (5Z)-9,15-dioxoprosta-5,8-dien-1-oate; natural products; Other biological molecules; Prostaglandins - isolation & purification; Sarcophyton crassocaule; Indian Ocean; Marine environment; Coelenterata; Prostaglandin; Cnidaria; Animal origin; Isolation; Diketone; Invertebrata; Dienic compound; Structural analysis; Cis stereoisomer
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np000148w

The rare prostaglandin methyl (5Z)-9,15-dioxoprosta-5,8(12)-dien-1-oate (1), hitherto unreported as a natural product, has been isolated from the Indian Ocean soft coral Sarcophyton crassocaule. Its structure was elucidated using detailed spectral (1H and 13C NMR, DEPT, H−H COSY, C−H COSY, HRMS, and HMBC) analysis.