Mercury Alters B‑Cell Protein Phosphorylation Profiles

Environmental exposure to mercury is suggested to contribute to human immune dysfunction. To shed light on the mechanism, we identified changes in the phosphoproteomic profile of the WEHI-231 B cell line after intoxication with Hg2+. These changes were compared to changes in the phosphoproteome that...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of proteome research Vol. 13; no. 2; pp. 496 - 505
Main Authors:	Caruthers, Nicholas J, Stemmer, Paul M, Shin, Namhee, Dombkowski, Alan, Caruso, Joseph A, Gill, Randal, Rosenspire, Allen
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 07-02-2014
Subjects:	B-Lymphocytes - drug effects B-Lymphocytes - metabolism Blood Proteins - metabolism Cell Line Chromatography, Affinity Humans Mercury - pharmacology Phosphorylation Tandem Mass Spectrometry toxicology phosphoproteomics phosphotyrosine B cell Hg2 phosphoprotein mercury WEHI-231 mass spectrometry TiO2
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!