A Modified Parallel Plate Flow Chamber to Study Local Endothelial Response to Recirculating Disturbed Flow

Atherosclerosis develops at arterial sites where endothelial cells (ECs) are exposed to low time-averaged shear stress, in particular in regions of recirculating disturbed flow. To understand how hemodynamics contributes to EC dysfunction in atheroma development, an in vitro parallel plate flow cham...

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Bibliographic Details

Published in:	Journal of biomechanical engineering Vol. 142; no. 4
Main Authors:	Sedlak, Jason Matthew, Clyne, Alisa Morss
Format:	Journal Article
Language:	English
Published:	United States 01-04-2020
Subjects:	Animals Cattle Cell Adhesion Cell Proliferation Endothelial Cells - cytology Hemodynamics Hydrodynamics Monocytes - cytology Nitric Oxide - metabolism Shear Strength Stress, Mechanical
Online Access:	Get more information
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