Preparing (Multi)Fluoroarenes as Building Blocks for Synthesis: Nickel-Catalyzed Borylation of Polyfluoroarenes via C–F Bond Cleavage

Preparing (Multi)Fluoroarenes as Building Blocks for Synthesis: Nickel-Catalyzed Borylation of Polyfluoroarenes via C–F Bond Cleavage

The [Ni­(IMes)2]-catalyzed transformation of fluoroarenes into arylboronic acid pinacol esters via C–F bond activation and transmetalation with bis­(pinacolato)­diboron (B2pin2) is reported. Various partially fluorinated arenes with different degrees of fluorination were converted into their corresp...

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Bibliographic Details
Published in:Journal of the American Chemical Society Vol. 138; no. 16; pp. 5250 - 5253
Main Authors: Zhou, Jing, Kuntze-Fechner, Maximilian W, Bertermann, Rüdiger, Paul, Ursula S. D, Berthel, Johannes H. J, Friedrich, Alexandra, Du, Zhenting, Marder, Todd B, Radius, Udo
Format: Journal Article
Language:English
Published: United States American Chemical Society 27-04-2016
Online Access:Get full text
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Summary:The [Ni­(IMes)2]-catalyzed transformation of fluoroarenes into arylboronic acid pinacol esters via C–F bond activation and transmetalation with bis­(pinacolato)­diboron (B2pin2) is reported. Various partially fluorinated arenes with different degrees of fluorination were converted into their corresponding boronate esters.
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content type line 23
ISSN:0002-7863
1520-5126
DOI:10.1021/jacs.6b02337