Simultaneous determination of nicotine and cotinine in human plasma by nitrogen detection gas-liquid chromatography

Human plasma levels of nicotine and its principal metabolite, cotinine, were simultaneously quantitated by gas-liquid chromatography combined with nitrogen selective detection. Nicotine, cotinine, and the added internal standard ketamine are extracted from plasma at basic pH into methylene chloride,...

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Bibliographic Details

Published in:	Journal of forensic sciences Vol. 26; no. 1; p. 6
Main Authors:	Kogan, M J, Verebey, K, Jaffee, J H, Mulé, S J
Format:	Journal Article
Language:	English
Published:	United States 01-01-1981
Subjects:	Chromatography, Gas - methods Cotinine - blood Humans Nicotine - blood Nitrogen - analysis Pyrrolidinones - blood
Online Access:	Get more information
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