Development of CCK-tetrapeptide analogs as potent and selective CCK-A receptor agonists

• Published in: Journal of medicinal chemistry Vol. 33; no. 11; pp. 2950 - 2952
• Main Authors: Shiosaki, Kazumi, Lin, Chun Wel, Kopecka, Hana, Craig, Richard, Wagenaar, Frank L, Bianchi, Bruce, Miller, Thomas, Witte, David, Nadzan, Alex M
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 01-11-1990
• Subjects: Amino Acid Sequence; Amylases - metabolism; Animals; Cerebral Cortex - metabolism; Chemistry; Cholecystokinin - analogs & derivatives; Cholecystokinin - chemical synthesis; Cholecystokinin - metabolism; Cholecystokinin - pharmacology; Exact sciences and technology; Guinea Pigs; Molecular Sequence Data; Molecular Structure; Oligopeptides - chemical synthesis; Oligopeptides - metabolism; Oligopeptides - pharmacology; Organic chemistry; Pancreas - drug effects; Pancreas - metabolism; Peptide Fragments - chemical synthesis; Peptide Fragments - metabolism; Peptide Fragments - pharmacology; Peptides; Preparations and properties; Receptors, Cholecystokinin - drug effects; Receptors, Cholecystokinin - metabolism; Structure-Activity Relationship; Tetragastrin - analogs & derivatives; Agonist; Tetrapeptide; Biological activity; Tripeptide; Biological receptor
• ISSN: 0022-2623; 1520-4804
• DOI: 10.1021/jm00173a006