Electrophilic Properties of Patulin. N-Acetylcysteine and Glutathione Adducts

In our studies on the electrophilic properties of the mycotoxin patulin (PAT), we have now investigated the nonenzymatic reaction of PAT with the thiol-containing tripeptide glutathione and its metabolic degradation product N-acetyl-l-cysteine (NAC). Adduct formation in aqueous phosphate buffer (pH...

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Bibliographic Details

Published in:	Chemical research in toxicology Vol. 13; no. 5; pp. 373 - 381
Main Authors:	Fliege, Ralph, Metzler, Manfred
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 01-05-2000
Subjects:	acetylcysteine Acetylcysteine - chemistry Chromatography, High Pressure Liquid electrophilic properties electrophilicity Glutathione - chemistry Molecular Structure Mutagens - chemistry patulin Patulin - chemistry
Online Access:	Get full text
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