Directed Ortho Borylation of Functionalized Arenes Catalyzed by a Silica-Supported Compact Phosphine−Iridium System

Directed Ortho Borylation of Functionalized Arenes Catalyzed by a Silica-Supported Compact Phosphine−Iridium System

An immobilized monophosphine−Ir system, which was prepared in situ from [Ir(OMe)(cod)]2 and a silica-supported, compact phosphine, showed high activities and selectivities for the borylation of aromatic C−H bonds with bis(pinacolato)diboron. This system was effective not only for the borylation of b...

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Bibliographic Details
Published in:Journal of the American Chemical Society Vol. 131; no. 14; pp. 5058 - 5059
Main Authors: Kawamorita, Soichiro, Ohmiya, Hirohisa, Hara, Kenji, Fukuoka, Atsushi, Sawamura, Masaya
Format: Journal Article
Language:English
Published: United States American Chemical Society 15-04-2009
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Summary:An immobilized monophosphine−Ir system, which was prepared in situ from [Ir(OMe)(cod)]2 and a silica-supported, compact phosphine, showed high activities and selectivities for the borylation of aromatic C−H bonds with bis(pinacolato)diboron. This system was effective not only for the borylation of benzene but also for the ortho borylation of arenes with directing groups, such as ester, amide, sulfonate, acetal, alkoxymethyl, and chloro groups, under mild reaction conditions.
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ISSN:0002-7863
1520-5126
DOI:10.1021/ja9008419