Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications

The cGAS-STING pathway plays a crucial role in innate immune activation against cancer and infections, and STING agonists based on cyclic dinucleotides (CDN) have garnered attention for their potential use in cancer immunotherapy and vaccines. However, the limited drug-like properties of CDN necessi...

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Bibliographic Details

Published in:	ACS nano Vol. 18; no. 15; pp. 10439 - 10453
Main Authors:	Sun, Xiaoqi, Huang, Xuehui, Park, Kyung Soo, Zhou, Xingwu, Kennedy, Andrew A., Pretto, Carla D., Wu, Qi, Wan, Ziye, Xu, Yao, Gong, Wang, Sexton, Jonathan Z., Tai, Andrew W., Lei, Yu Leo, Moon, James J.
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 16-04-2024
Subjects:	coordination nanoparticle STING vaccine cyclic dinucleotide cancer immunotherapy
Online Access:	Get full text
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