Pellicle Biofilm Formation in Burkholderia cenocepacia J2315 is Epigenetically Regulated through WspH, a Hybrid Two-Component System Kinase-Response Regulator

The chemosensory signal transduction system Wsp regulates biofilm formation and related phenotypes by influencing cyclic-di-GMP (c-di-GMP) levels in bacterial cells. This is typically achieved by activation of the diguanylate cyclase WspR, through phosphorylation of its phosphoreceiver domain. The W...

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Bibliographic Details
Published in:	Journal of bacteriology Vol. 204; no. 5; p. e0001722
Main Authors:	Sass, Andrea, Vandenbussche, Ian, Bellich, Barbara, Cescutti, Paola, Coenye, Tom
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 17-05-2022
Subjects:	Anti-Bacterial Agents - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacteriology Biofilms Burkholderia cenocepacia Burkholderia cenocepacia - metabolism Chemoreception Cyclic GMP - metabolism Gene Expression Regulation, Bacterial Histidine Histidine kinase Histidine Kinase - genetics Histidine Kinase - metabolism Humans Hybrid systems Kinases Mutants Oxygen - metabolism Pellicle Phenotypes Phosphorylation Research Article Signal transduction Swimming c-di-GMP Burkholderia Wsp biofilm
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