Tumor-Selective Immune-Active Mild Hyperthermia Associated with Chemotherapy in Colon Peritoneal Metastasis by Photoactivation of Fluorouracil–Gold Nanoparticle Complexes

Peritoneal metastasis (PM) is considered as the terminal stage of metastatic colon cancer, with still poor median survival rate even with the best recent chemotherapy treatment. The current PM treatment combines cytoreductive surgery, which consists of resecting all macroscopic tumors, with hyperthe...

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Bibliographic Details
Published in:	ACS nano Vol. 15; no. 2; pp. 3330 - 3348
Main Authors:	Mulens-Arias, Vladimir, Nicolás-Boluda, Alba, Pinto, Amandine, Balfourier, Alice, Carn, Florent, Silva, Amanda K. A, Pocard, Marc, Gazeau, Florence
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 23-02-2021
Subjects:	Animals Antineoplastic Combined Chemotherapy Protocols Colonic Neoplasms - drug therapy Combined Modality Therapy Fluorouracil - therapeutic use Gold - therapeutic use Hyperthermia Hyperthermia, Induced Life Sciences Metal Nanoparticles Mice Peritoneal Neoplasms - drug therapy Tumor Microenvironment 5-fluorouracil gold nanoparticles peritoneal metastasis photothermal therapy carcinomatosis
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