Stereodivergence in Asymmetric Catalysis

Stereodivergence in Asymmetric Catalysis

This Perspective presents an overview of catalytic enantio­selective transformations that allow convenient access to all stereo­isomers of a given product with multiple stereo­genic centers. Particular focus is placed on discussion of the concept of stereo­divergent dual catalysis and its applicatio...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Chemical Society Vol. 139; no. 16; pp. 5627 - 5639
Main Authors: Krautwald, Simon, Carreira, Erick M
Format: Journal Article
Language:English
Published: United States American Chemical Society 26-04-2017
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This Perspective presents an overview of catalytic enantio­selective transformations that allow convenient access to all stereo­isomers of a given product with multiple stereo­genic centers. Particular focus is placed on discussion of the concept of stereo­divergent dual catalysis and its application in target-oriented synthesis. The potential of this concept in the development of new transformations as well as implications for achieving stereo­chemical diversity in library design and diversity-oriented synthesis are also discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0002-7863
1520-5126
DOI:10.1021/jacs.6b13340