Tree Species-Dependent Inactivation of Coronaviruses and Enteroviruses on Solid Wood Surfaces

• Published in: ACS applied materials & interfaces Vol. 16; no. 23; pp. 29621 - 29633
• Main Authors: Shroff, Sailee, Perämäki, Anni, Väisänen, Antti, Pasanen, Pertti, Grönlund, Krista, Nissinen, Ville H., Jänis, Janne, Haapala, Antti, Marjomäki, Varpu
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 12-06-2024
• Subjects: antiviral; Antiviral Agents - chemistry; Antiviral Agents - pharmacology; Biological and Medical Applications of Materials and Interfaces; coronavirus; Coronavirus - drug effects; enterovirus; Enterovirus - drug effects; Humans; persistence; Picea - chemistry; Pinus - chemistry; Quercus - chemistry; solid surface; Surface Properties; Trees - virology; Virus Inactivation - drug effects; wood; Wood - chemistry; solid surface; coronavirus; persistence; wood; enterovirus; antiviral
• ISSN: 1944-8244; 1944-8252; 1944-8252
• DOI: 10.1021/acsami.4c02156

The ongoing challenge of viral transmission, exemplified by the Covid pandemic and recurrent viral outbreaks, necessitates the exploration of sustainable antiviral solutions. This study investigates the underexplored antiviral potential of wooden surfaces. We evaluated the antiviral efficacy of various wood types, including coniferous and deciduous trees, against enveloped coronaviruses and nonenveloped enteroviruses like coxsackie virus A9. Our findings revealed excellent antiviral activity manifesting already within 10 to 15 min in Scots pine and Norway spruce, particularly against enveloped viruses. In contrast, other hardwoods displayed varied efficacy, with oak showing effectiveness against the enterovirus. This antiviral activity was consistently observed across a spectrum of humidity levels (20 to 90 RH%), while the antiviral efficacy manifested itself more rapidly at 37 °C vs 21 °C. Key to our findings is the chemical composition of these woods. Resin acids and terpenes were prevalent in pine and spruce, correlating with their antiviral performance, while oak’s high phenolic content mirrored its efficacy against enterovirus. The pine surface absorbed a higher fraction of the coronavirus in contrast to oak, whereas enteroviruses were not absorbed on those surfaces. Thermal treatment of wood or mixing wood with plastic, such as in wood-plastic composites, strongly compromised the antiviral functionality of wood materials. This study highlights the role of bioactive chemicals in the antiviral action of wood and opens new avenues for employing wood surfaces as a natural and sustainable barrier against viral transmissions.