Living Biomaterials
Convergent advances in the fields of synthetic chemistry, soft matter, molecular self-assembly, and the -omics era point to a new generation of synthetic biomaterials that are indistinguishable in form and function from biological matter. Such living biomaterials comprise a “Holy Grail” of the chemi...
Saved in:
| Published in: | Accounts of chemical research Vol. 50; no. 3; pp. 508 - 513 |
|---|---|
| Main Authors: | , |
| Format: | Journal Article |
| Language: | English |
| Published: |
United States
American Chemical Society
21-03-2017
|
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Convergent advances in the fields of synthetic chemistry, soft matter, molecular self-assembly, and the -omics era point to a new generation of synthetic biomaterials that are indistinguishable in form and function from biological matter. Such living biomaterials comprise a “Holy Grail” of the chemical sciences that will transform both modern medicine and materials design. |
|---|---|
| AbstractList | Convergent advances in the fields of synthetic chemistry, soft matter, molecular self-assembly, and the -omics era point to a new generation of synthetic biomaterials that are indistinguishable in form and function from biological matter. Such living biomaterials comprise a “Holy Grail” of the chemical sciences that will transform both modern medicine and materials design. |
| Author | Langer, Robert Tibbitt, Mark W |
| AuthorAffiliation | Massachusetts Institute of Technology Department of Chemical Engineering David H. Koch Institute for Integrative Cancer Research |
| AuthorAffiliation_xml | – name: Department of Chemical Engineering – name: David H. Koch Institute for Integrative Cancer Research – name: Massachusetts Institute of Technology |
| Author_xml | – sequence: 1 givenname: Mark W orcidid: 0000-0002-4917-7187 surname: Tibbitt fullname: Tibbitt, Mark W organization: Massachusetts Institute of Technology – sequence: 2 givenname: Robert orcidid: 0000-0003-4255-0492 surname: Langer fullname: Langer, Robert email: rlanger@mit.edu organization: Massachusetts Institute of Technology |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28945422$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kL1PwzAQxS1URNPCxIoQI0uCPy6OPULFlxSJBWbLjh2UqomLnSDx3-OqLSPT3Unv_U7vLdBs8IND6IrggmBK7nQTC900fhrGWHCDMUh5gjJSUpyDkGKGMowxSTvQOVrEuE4nBV6doTkVEkqgNEOXdffdDZ83D53v9ehCpzfxHJ22abiLw1yij6fH99VLXr89v67u61wzEGNugZeGOU2ptYkFHJhpBQVXsgZXXMvKUC2MYLbSAgzjkljHwVnQRLclYUt0u-dug_-aXBxV38XGbTZ6cH6KikhgNAEJTlLYS5vgYwyuVdvQ9Tr8KILVrg6V6lDHOtShjmS7PnyYTO_sn-mYPwnwXrCzr_0UhhT4f-Yvn5FvCg |
| CitedBy_id | crossref_primary_10_1021_acsami_8b03506 crossref_primary_10_1016_j_cossms_2018_11_002 crossref_primary_10_1016_j_cobme_2023_100493 crossref_primary_10_3390_ma12071049 crossref_primary_10_1016_j_mtchem_2018_12_001 crossref_primary_10_1016_j_tibtech_2018_01_005 crossref_primary_10_1021_acsami_2c12918 crossref_primary_10_1080_25740881_2018_1563117 crossref_primary_10_1002_ange_201708857 crossref_primary_10_1016_j_heliyon_2020_e03798 crossref_primary_10_1039_D3BM00046J crossref_primary_10_1021_acs_macromol_0c00030 crossref_primary_10_1126_scitranslmed_aam8645 crossref_primary_10_1039_C9TC01483G crossref_primary_10_1021_jacs_2c04418 crossref_primary_10_1021_jacs_2c12491 crossref_primary_10_1002_adfm_202108057 crossref_primary_10_1007_s10924_023_03162_9 crossref_primary_10_1016_j_xcrp_2024_102022 crossref_primary_10_3390_ijms23169117 crossref_primary_10_1002_app_47151 crossref_primary_10_1021_acsmaterialslett_0c00224 crossref_primary_10_1038_s41413_020_00131_z crossref_primary_10_1021_acsbiomaterials_8b00889 crossref_primary_10_1039_D0SM02285C crossref_primary_10_1039_D3TB00701D crossref_primary_10_3390_gels8120769 crossref_primary_10_1016_j_biomaterials_2024_122683 crossref_primary_10_1002_adma_201901994 crossref_primary_10_1089_jop_2018_0142 crossref_primary_10_1080_00914037_2019_1581197 crossref_primary_10_1002_chem_201804765 crossref_primary_10_1080_14712598_2019_1610383 crossref_primary_10_3389_fbioe_2020_00126 crossref_primary_10_3390_pr9111949 crossref_primary_10_1016_j_ebiom_2021_103717 crossref_primary_10_1016_j_biomaterials_2018_07_020 crossref_primary_10_1021_acs_cgd_8b00012 crossref_primary_10_1039_C7PY00698E crossref_primary_10_1039_C8CC10021G crossref_primary_10_1016_j_eurpolymj_2020_109703 crossref_primary_10_1039_D0BM01255F crossref_primary_10_1021_acs_chemmater_8b03860 crossref_primary_10_3390_polym13162590 crossref_primary_10_1038_s41573_023_00671_z crossref_primary_10_1016_j_scitotenv_2022_153857 |
| Cites_doi | 10.1038/nature14272 10.1073/pnas.1314651111 10.1016/j.biomaterials.2008.01.035 10.1038/nm.4030 10.1038/nmat3889 10.1021/jacs.5b12953 10.1038/16898 10.1073/pnas.1505405112 10.1021/nl034095p 10.1016/j.biomaterials.2010.10.020 10.1126/science.1241888 10.1039/c2cs35264h 10.1038/nmat4671 10.1002/adma.201504152 10.1038/nbt.3071 10.1038/nature03496 10.1126/science.1099987 10.1126/science.1261172 10.1126/science.aaf3639 10.1038/nature18930 10.1371/journal.pone.0135148 10.1038/nature09963 10.1038/srep21387 10.1038/ncomms9094 10.1126/scitranslmed.aad0293 10.1038/nature19776 10.1073/pnas.1317233111 |
| ContentType | Journal Article |
| Copyright | Copyright © 2017 American Chemical Society |
| Copyright_xml | – notice: Copyright © 2017 American Chemical Society |
| DBID | NPM AAYXX CITATION 7X8 |
| DOI | 10.1021/acs.accounts.6b00499 |
| DatabaseName | PubMed CrossRef MEDLINE - Academic |
| DatabaseTitle | PubMed CrossRef MEDLINE - Academic |
| DatabaseTitleList | PubMed MEDLINE - Academic |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EISSN | 1520-4898 |
| EndPage | 513 |
| ExternalDocumentID | 10_1021_acs_accounts_6b00499 28945422 b18150577 |
| Genre | Journal Article Research Support, N.I.H., Extramural |
| GroupedDBID | - .K2 02 23M 53G 55A 5GY 5VS 7~N 85S AABXI ABFLS ABMVS ABPTK ABUCX ABUFD ACGFS ACJ ACNCT ACS AEESW AENEX AETEA AFEFF ALMA_UNASSIGNED_HOLDINGS AQSVZ BAANH CS3 D0L DZ EBS ED ED~ EJD F5P GNL IH9 JG JG~ K2 LG6 P2P RNS ROL TWZ UI2 UPT VF5 VG9 W1F WH7 X YZZ --- -DZ -~X 4.4 5ZA 6J9 6P2 ABJNI ABQRX ACGFO ADHLV AFXLT AGXLV AHGAQ CUPRZ GGK IH2 NPM XSW ZCA ~02 AAYXX CITATION 7X8 |
| ID | FETCH-LOGICAL-a348t-d465b3ea22dd4224643bf824e53c076a97b2a8b83d7a84b3691de64ed4a1af513 |
| IEDL.DBID | ACS |
| ISSN | 0001-4842 |
| IngestDate | Fri Oct 25 22:46:59 EDT 2024 Thu Sep 26 19:16:26 EDT 2024 Wed Oct 16 00:58:16 EDT 2024 Thu Aug 27 13:42:22 EDT 2020 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-a348t-d465b3ea22dd4224643bf824e53c076a97b2a8b83d7a84b3691de64ed4a1af513 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0003-4255-0492 0000-0002-4917-7187 |
| PMID | 28945422 |
| PQID | 1943282410 |
| PQPubID | 23479 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_1943282410 crossref_primary_10_1021_acs_accounts_6b00499 pubmed_primary_28945422 acs_journals_10_1021_acs_accounts_6b00499 |
| ProviderPackageCode | JG~ 55A AABXI GNL VF5 7~N ACJ VG9 W1F ACS AEESW AFEFF .K2 ABMVS ABUCX IH9 BAANH AQSVZ ED~ UI2 |
| PublicationCentury | 2000 |
| PublicationDate | 2017-03-21 |
| PublicationDateYYYYMMDD | 2017-03-21 |
| PublicationDate_xml | – month: 03 year: 2017 text: 2017-03-21 day: 21 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Accounts of chemical research |
| PublicationTitleAlternate | Acc. Chem. Res |
| PublicationYear | 2017 |
| Publisher | American Chemical Society |
| Publisher_xml | – name: American Chemical Society |
| References | ref9/cit9 ref6/cit6 ref3/cit3 ref27/cit27 Langer R. (ref15/cit15) 1998; 392 ref18/cit18 ref11/cit11 ref25/cit25 ref16/cit16 ref29/cit29 ref23/cit23 ref14/cit14 ref8/cit8 ref2/cit2 ref28/cit28 ref20/cit20 ref17/cit17 ref10/cit10 ref26/cit26 ref19/cit19 ref21/cit21 ref12/cit12 Staudinger H. (ref5/cit5) 1953 ref22/cit22 ref13/cit13 ref4/cit4 ref1/cit1 ref24/cit24 ref7/cit7 |
| References_xml | – ident: ref26/cit26 doi: 10.1038/nature14272 – ident: ref20/cit20 doi: 10.1073/pnas.1314651111 – ident: ref11/cit11 doi: 10.1016/j.biomaterials.2008.01.035 – ident: ref14/cit14 doi: 10.1038/nm.4030 – ident: ref3/cit3 doi: 10.1038/nmat3889 – ident: ref9/cit9 doi: 10.1021/jacs.5b12953 – ident: ref2/cit2 doi: 10.1038/16898 – ident: ref16/cit16 doi: 10.1073/pnas.1505405112 – ident: ref8/cit8 doi: 10.1021/nl034095p – volume: 392 start-page: 5 year: 1998 ident: ref15/cit15 publication-title: Nature contributor: fullname: Langer R. – ident: ref12/cit12 doi: 10.1016/j.biomaterials.2010.10.020 – ident: ref28/cit28 doi: 10.1126/science.1241888 – start-page: 397 year: 1953 ident: ref5/cit5 publication-title: Nobel Lecture contributor: fullname: Staudinger H. – ident: ref6/cit6 doi: 10.1039/c2cs35264h – ident: ref22/cit22 doi: 10.1038/nmat4671 – ident: ref25/cit25 doi: 10.1002/adma.201504152 – ident: ref17/cit17 doi: 10.1038/nbt.3071 – ident: ref4/cit4 doi: 10.1038/nature03496 – ident: ref1/cit1 doi: 10.1126/science.1099987 – ident: ref10/cit10 doi: 10.1126/science.1261172 – ident: ref29/cit29 doi: 10.1126/science.aaf3639 – ident: ref19/cit19 doi: 10.1038/nature18930 – ident: ref24/cit24 doi: 10.1371/journal.pone.0135148 – ident: ref7/cit7 doi: 10.1038/nature09963 – ident: ref13/cit13 doi: 10.1038/srep21387 – ident: ref18/cit18 doi: 10.1038/ncomms9094 – ident: ref21/cit21 doi: 10.1126/scitranslmed.aad0293 – ident: ref27/cit27 doi: 10.1038/nature19776 – ident: ref23/cit23 doi: 10.1073/pnas.1317233111 |
| SSID | ssj0002467 |
| Score | 2.4870522 |
| Snippet | Convergent advances in the fields of synthetic chemistry, soft matter, molecular self-assembly, and the -omics era point to a new generation of synthetic... |
| SourceID | proquest crossref pubmed acs |
| SourceType | Aggregation Database Index Database Publisher |
| StartPage | 508 |
| Title | Living Biomaterials |
| URI | http://dx.doi.org/10.1021/acs.accounts.6b00499 https://www.ncbi.nlm.nih.gov/pubmed/28945422 https://search.proquest.com/docview/1943282410 |
| Volume | 50 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV07T8MwED5BGWDhUV7lpSKxMLjU9sV2RiitOiCWgsQW-RWpS4pI-_-x86jEUKGukXXxXU6-73K-7wAeEHPuk0QSLbUkkbCLaOFzItFSJb3grqIvns7k-5d6HUeanMGGCj6jT9qWQXQ1OaEciOpqTroLe0wGsBCh0Gi2PnkZipojM6TIqJC1rXIbpMSAZMu_AWkDyqyizeRo230ew2GDK_vPtSOcwI4vurA_ase5nUL3bR7_HfRf5osAUmu_O4PPyfhjNCXNRASiOaolccGYhnvNmHMYqeCQm1wx9Am3Qyl0Kg3TyijupFZouEip8wK9Q011nlB-Dp1iUfhL6NPE2tSbXAyrXlRrtLYiNg0mykibmh48Bo2yxqPLrCpWM5rFh62aWaNmD0hrwuy7Jsn4Z_19a-csWCGWKHThF6vwlhR5SAKRDntwUX-AtcSQGmIStL7aYmfXcMBiHB5ywugNdJY_K38Lu6Vb3VWu8wvU77-2 |
| link.rule.ids | 315,782,786,2769,27085,27933,27934,56747,56797 |
| linkProvider | American Chemical Society |
| linkToHtml | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT8MwDLZgHMaFx3iN55C4cAg07_QIY9MQY5cNiVuVpKm0y4bo9v9J-hjiMCG4RpVru1b9ua4_A9wwllHHuURaaokCYRfSwmVIMouVdIKmBX3xYCxH7-qpF2hyeD0L45XIvaS8aOJ_swvg-3CmywUK-Z0o_tCJN2GLC4-HAyLqjlcvYMJESZXpK2WmGKkn5tZICXnJ5j_z0hqwWSSd_u4_1d2DnQpldh7KsNiHDTdrQbNbL3c7gNZwGr4kdB6ncw9Zyyg8hLd-b9IdoGo_AtKUqQVKvWsNdZqQNGWBGI5RkynCHKc2kkLH0hCtjKKp1IoZKmKcOsFcyjTWGcf0CBqz-cydQAdza2NnMhEVk6nWaG1FGCHkykgbmzbceouSKr7zpGhdE5yEw9rMpDKzDaj2ZPJRUmb8cv117e7EeyE0LPTMzZf-LjGjviRkOGrDcfkcVhJ9oci4t_r0D5pdQXMweR0mw-fRyxlsk5ChI4oIPofG4nPpLmAzT5eXRTR9Ae98yCM |
| linkToPdf | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT8MwDLbYkIALj_EazyFx4RBoHk3S49hDQ0wT0kDiViVNKu3STXT7_yR9TOIwIcQ1qlzbdWK7jj8D3DOWUhuGAimhBPKAXUhxmyLBEiyF5dQU8MWjqZh8yv7Aw-SsR305JnJHKS-K-H5XL0xaIQzgJ7-uyiEK-SMvbulEDdgOuYh83tXtTdeHMGG8hMt02TKTjNRdcxuoeN-U5D9904aAs3A8w4N_sHwI-1W02emW5nEEWzZrwW6vHvJ2DK3xzP9R6DzP5i50La3xBD6Gg_feCFVzEpCiTC6RcSrW1CpCjGEeII5RnUrCbEiTQHAVCU2U1JIaoSTTlEfYWM6sYQqrNMT0FJrZPLPn0MFhkkRWpzwoOlQTrVTCfSthKLVIIt2GBydRXNl5HhclbIJjv1iLGVditgHV2owXJXTGL8_f1SqPnRZ84UJldr5yb4kYdakhw0EbzspvsaboEkYWOqkv_sDZLey89Yfx-GXyegl7xDvqgCKCr6C5_FrZa2jkZnVTGNQ3owHKpg |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Living+Biomaterials&rft.jtitle=Accounts+of+chemical+research&rft.au=Tibbitt%2C+Mark+W&rft.au=Langer%2C+Robert&rft.date=2017-03-21&rft.eissn=1520-4898&rft.volume=50&rft.issue=3&rft.spage=508&rft.epage=513&rft_id=info:doi/10.1021%2Facs.accounts.6b00499&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0001-4842&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0001-4842&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0001-4842&client=summon |