Cybastacines A and B: Antibiotic Sesterterpenes from a Nostoc sp. Cyanobacterium

Cybastacines A and B: Antibiotic Sesterterpenes from a Nostoc sp. Cyanobacterium

Cybastacines A (1) and B (2) were discovered as a novel pentacyclic sesterterpenoid–alkaloid skeleton structure, with a guanidinium group. These molecules were isolated from a Nostoc sp. cyanobacterium collected in the Canary Islands. Their structures were elucidated primarily by a combination of sp...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) Vol. 81; no. 2; pp. 410 - 413
Main Authors: Cabanillas, Alfredo H, Tena Pérez, Víctor, Maderuelo Corral, Santiago, Rosero Valencia, Diego Fernando, Martel Quintana, Antera, Ortega Doménech, Montserrat, Rumbero Sánchez, Ángel
Format: Journal Article
Language:English
Published: United States American Chemical Society and American Society of Pharmacognosy 23-02-2018
Online Access:Get full text
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Summary:Cybastacines A (1) and B (2) were discovered as a novel pentacyclic sesterterpenoid–alkaloid skeleton structure, with a guanidinium group. These molecules were isolated from a Nostoc sp. cyanobacterium collected in the Canary Islands. Their structures were elucidated primarily by a combination of spectroscopic analyses and X-ray diffraction. These compounds showed antibiotic activities against several clinically relevant bacterial strains.
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ISSN:0163-3864
1520-6025
DOI:10.1021/acs.jnatprod.7b00638