Multitechnique screening of Chicago municipal sewage sludge for mutagenic activity

Multitechnique screening of Chicago municipal sewage sludge for mutagenic activity

Anaerobically digested sludge was subjected to a multi-organism screening procedure to determine whether mutagenic compounds are present in sludge and sludge-amended soil. The sludge was shown to contain components that induce mutagenic responses in all the species employed in the bioassays. Acetone...

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Bibliographic Details
Published in:Environmental science & technology Vol. 16; no. 3; pp. 140 - 147
Main Authors: Hopke, Philip K, Plewa, Michael J, Johnston, James B, Weaver, Danny, Wood, Susanne G, Larson, Richard A, Hinesly, Thomas
Format: Journal Article
Language:English
Published: American Chemical Society 01-03-1982
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Summary:Anaerobically digested sludge was subjected to a multi-organism screening procedure to determine whether mutagenic compounds are present in sludge and sludge-amended soil. The sludge was shown to contain components that induce mutagenic responses in all the species employed in the bioassays. Acetone extracts from neat sludge doubled the number of revertant colonies of the Ames Salmonella strain after activation with mammalian microsomes, while point mutations were induced in the germ cells of Zea mays. Cytogenetic damage was observed in meiotic cells of Tradescantia paludosa .
Bibliography:istex:412C405970EAE736A63CBE7163B3EBB0B90172B4
ark:/67375/TPS-R9PVTD3X-W
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0013-936X
1520-5851
DOI:10.1021/es00097a005