Copper-Free Synthesis of Skipped Diynes via Cross-Coupling Reactions of Alkynylalanes with Propargylic Electrophiles

Alkynylalanes provide a new, copper-free route to skipped diynes when combined with propargylic electrophiles bearing an aluminum-complexing leaving group. The reaction is mild, efficient, and, in contrast to copper-mediated methods, highly regioselective.

Bibliographic Details

Published in:	Organic letters Vol. 8; no. 24; pp. 5629 - 5632
Main Authors:	Kessabi, Jilali, Beaudegnies, Renaud, Jung, Pierre M. J, Martin, Benjamin, Montel, Florian, Wendeborn, Sebastian
Format:	Journal Article
Language:	English
Published:	United States American Chemical Society 23-11-2006
Online Access:	Get full text
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