Solid-Phase Total Synthesis of Oscillamide Y and Analogues

We report an efficient solid phase synthesis of oscillamide Y and three analogues. The cyclic peptide was prepared using a combination of Fmoc and allyl chemistries and an acid labile Wang type linker. The urea functionality was smoothly incorporated using N α-(4-nitrophenyloxycarbonyl)-N ε-(9-fluor...

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Bibliographic Details
Published in:Journal of organic chemistry Vol. 62; no. 18; pp. 6199 - 6203
Main Authors: Marsh, Ian R, Bradley, Mark, Teague, Simon J
Format: Journal Article
Language:English
Published: American Chemical Society 05-09-1997
Online Access:Get full text
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