meso-Pyrimidinyl-Substituted A2B- and A3-Corroles

A variety of meso-pyrimidinyl-substituted A2B- and A3-corroles (A = 4,6-dichloropyrimidin-5-yl) have been synthesized by careful optimization of the macrocyclization conditions. meso-Pyrimidinylcorroles offer the distinct advantage of an unprecedented broad scope of functionalization options. Highly...

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Published in:	Journal of organic chemistry Vol. 75; no. 6; pp. 2127 - 2130
Main Authors:	Ngo, Thien H, Nastasi, Francesco, Puntoriero, Fausto, Campagna, Sebastiano, Dehaen, Wim, Maes, Wouter
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 19-03-2010
Subjects:	Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Organic chemistry Preparations and properties Suzuki coupling Functionalization Nitrogen heterocycle Macrocyclization Pyrimidine derivatives Steric hindrance Metallocorrole Nucleophilic substitution Chemical synthesis Optimization SNAr mechanism
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Abstract	A variety of meso-pyrimidinyl-substituted A2B- and A3-corroles (A = 4,6-dichloropyrimidin-5-yl) have been synthesized by careful optimization of the macrocyclization conditions. meso-Pyrimidinylcorroles offer the distinct advantage of an unprecedented broad scope of functionalization options. Highly sterically encumbered triarylcorroles were readily prepared via efficient nucleophilic aromatic substitution and Suzuki cross-coupling procedures.
AbstractList	A variety of meso-pyrimidinyl-substituted A2B- and A3-corroles (A = 4,6-dichloropyrimidin-5-yl) have been synthesized by careful optimization of the macrocyclization conditions. meso-Pyrimidinylcorroles offer the distinct advantage of an unprecedented broad scope of functionalization options. Highly sterically encumbered triarylcorroles were readily prepared via efficient nucleophilic aromatic substitution and Suzuki cross-coupling procedures. A variety of meso-pyrimidinyl-substituted A(2)B- and A(3)-corroles (A = 4,6-dichloropyrimidin-5-yl) have been synthesized by careful optimization of the macrocyclization conditions. meso-Pyrimidinylcorroles offer the distinct advantage of an unprecedented broad scope of functionalization options. Highly sterically encumbered triarylcorroles were readily prepared via efficient nucleophilic aromatic substitution and Suzuki cross-coupling procedures.
Author	Dehaen, Wim Ngo, Thien H Maes, Wouter Puntoriero, Fausto Nastasi, Francesco Campagna, Sebastiano
Author_xml	– sequence: 1 givenname: Thien H surname: Ngo fullname: Ngo, Thien H – sequence: 2 givenname: Francesco surname: Nastasi fullname: Nastasi, Francesco – sequence: 3 givenname: Fausto surname: Puntoriero fullname: Puntoriero, Fausto – sequence: 4 givenname: Sebastiano surname: Campagna fullname: Campagna, Sebastiano – sequence: 5 givenname: Wim surname: Dehaen fullname: Dehaen, Wim email: wim.dehaen@chem.kuleuven.be – sequence: 6 givenname: Wouter surname: Maes fullname: Maes, Wouter
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Keywords	Suzuki coupling Functionalization Nitrogen heterocycle Macrocyclization Pyrimidine derivatives Steric hindrance Metallocorrole Nucleophilic substitution Chemical synthesis Optimization SNAr mechanism
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Snippet	A variety of meso-pyrimidinyl-substituted A2B- and A3-corroles (A = 4,6-dichloropyrimidin-5-yl) have been synthesized by careful optimization of the... A variety of meso-pyrimidinyl-substituted A(2)B- and A(3)-corroles (A = 4,6-dichloropyrimidin-5-yl) have been synthesized by careful optimization of the...
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SubjectTerms	Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with several n hetero atoms in the same ring, in separated rings or in fused rings Organic chemistry Preparations and properties
Title	meso-Pyrimidinyl-Substituted A2B- and A3-Corroles
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