Testing Pesticides in Humans: Of Mice and Men Divided by Ten

Breaking with a long tradition in the ethics of human experimentation that distinguished therapeutic from nontherapeutic agents, the Environmental Protection Agency (EPA) published a final rule in February 2006 on ethical guidelines for enrolling human participants in testing pesticides. The policy...

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Bibliographic Details
Published in:	JAMA : the journal of the American Medical Association Vol. 297; no. 21; pp. 2405 - 2407
Main Authors:	Krimsky, Sheldon, Simoncelli, Tania
Format:	Journal Article
Language:	English
Published:	United States American Medical Association 06-06-2007
Subjects:	Animals Codes of Ethics Government Regulation Guidelines Human subjects Humans Informed Consent - ethics Informed Consent - legislation & jurisprudence Medical ethics Morals Nontherapeutic Human Experimentation - ethics Nontherapeutic Human Experimentation - legislation & jurisprudence Pesticides Pesticides - toxicity Testing United States United States Environmental Protection Agency United States
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Summary:	Breaking with a long tradition in the ethics of human experimentation that distinguished therapeutic from nontherapeutic agents, the Environmental Protection Agency (EPA) published a final rule in February 2006 on ethical guidelines for enrolling human participants in testing pesticides. The policy gives regulatory standing to experiments that intentionally expose adults to toxic pesticides and could set a precedent for similar experiments involving other industrial chemicals. Krimsky and Simoncelli question this issue.
ISSN:	0098-7484 1538-3598
DOI:	10.1001/jama.297.21.2405