Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia

Frontal fibrosing alopecia (FFA) is an increasingly prevalent form of follicular lichen planus, causing irreversible hair loss predominantly in postmenopausal individuals. An earlier genome-wide meta-analysis of female FFA identified risk loci in genes implicated in self-antigen presentation and T-c...

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Bibliographic Details
Published in:	JAMA dermatology (Chicago, Ill.) Vol. 160; no. 7; p. 732
Main Authors:	Rayinda, Tuntas, McSweeney, Sheila M, Christou, Evangelos, Ung, Chuin Ying, Fenton, David A, McGrath, John A, Dand, Nick, Simpson, Michael A, Tziotzios, Christos
Format:	Journal Article
Language:	English
Published:	United States 01-07-2024
Subjects:	Adult Aged Alopecia - genetics Case-Control Studies Contraceptives, Oral - administration & dosage Contraceptives, Oral - adverse effects Cytochrome P-450 CYP1B1 - genetics Cytochrome P-450 CYP1B1 - metabolism Female Gene-Environment Interaction Genetic Predisposition to Disease Humans Lichen Planus - genetics Middle Aged Mutation, Missense United Kingdom - epidemiology United Kingdom
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