IncA/C Plasmid Carrying blaNDM-1, blaCMY-16, and fosA3 in a Salmonella enterica Serovar Corvallis Strain Isolated from a Migratory Wild Bird in Germany

• Published in: Antimicrobial agents and chemotherapy Vol. 59; no. 10; pp. 6597 - 6600
• Main Authors: Villa, L, Guerra, B, Schmoger, S, Fischer, J, Helmuth, R, Zong, Z, García-Fernández, A, Carattoli, A
• Format: Journal Article
• Language: English
• Published: 1752 N St., N.W., Washington, DC American Society for Microbiology 18-09-2015
• Subjects: Mechanisms of Resistance; Plasmids; Salmonella enterica
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.00944-15

A Salmonella enterica serovar Corvallis strain was isolated from a wild bird in Germany. This strain carried the IncA/C2 pRH-1238 plasmid. Complete sequencing of the plasmid was performed, identifying the blaNDM-1, blaCMY-16, fosA3, sul1, sul2, strA, strB, aac(6′)-Ib, aadA5, aphA6, tetA(A), mphA, floR, dfrA7, and merA genes, which confer clinically relevant resistance to most of the antimicrobial classes, including β-lactams with carbapenems, fosfomycin, aminoglycosides, co-trimoxazole, tetracyclines, and macrolides. The strain likely originated from the Asiatic region and was transferred to Germany through the Milvus migrans migratory route.