64Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor

This purpose of this study is to determine the efficacy of a 45-amino acid Gp2 domain, engineered to bind to epidermal growth factor receptor (EGFR), as a positron emission tomography (PET) probe of EGFR in a xenograft mouse model. The EGFR-targeted Gp2 (Gp2-EGFR) and a nonbinding control were site-...

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Bibliographic Details

Published in:	Molecular pharmaceutics Vol. 13; no. 11; pp. 3747 - 3755
Main Authors:	Kruziki, Max A, Case, Brett A, Chan, Jie Y, Zudock, Elizabeth J, Woldring, Daniel R, Yee, Douglas, Hackel, Benjamin J
Format:	Journal Article
Language:	English
Published:	American Chemical Society 07-11-2016
Subjects:	epidermal growth factor receptor imaging murine model micropositron emission tomography Gp2 domain protein scaffold
Online Access:	Get full text
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