Safety and Efficacy of Lamivudine-Zidovudine Combination Therapy in Antiretroviral-Naive Patients: A Randomized Controlled Comparison With Zidovudine Monotherapy

Objective.—To compare safety and efficacy of lamivudine-zidovudine combination therapy with zidovudine monotherapy in treating human immunodeficiency virus type 1 (HIV-1)—infected, antiretroviral therapy—naive patients.Design.—Double=blind, randomized, multicenter, comparative trial of 129 patients...

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Bibliographic Details
Published in:	JAMA : the journal of the American Medical Association Vol. 276; no. 2; pp. 118 - 125
Main Authors:	Katlama, Christine, Ingrand, Didier, Loveday, Clive, Clumeck, Nathan, Mallolas, Jose, Staszewski, Schlomo, Johnson, Margaret, Hill, Andrew M, Pearce, Gill, McDade, Hugh
Format:	Journal Article
Language:	English
Published:	Chicago, IL American Medical Association 10-07-1996
Subjects:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences human immunodeficiency virus 1 Medical sciences Pharmacology. Drug treatments Europe Human Immunopathology HIV-1 virus Treatment efficiency Multicenter study Retroviridae AIDS Immune deficiency Infection Virus Chemotherapy Association Efficiency Viral disease Lentivirinae Antiviral Clinical trial Human immunodeficiency virus Safety Pyrimidine nucleoside Comparative study
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