Search Results - Yendluri, Satya

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S] by Jensen, Kristian K., Tadin-Strapps, Marija, Wang, Sheng-ping, Hubert, James, Kan, Yanqing, Ma, Yong, McLaren, David G., Previs, Stephen F., Herath, Kithsiri B., Mahsut, Ablatt, Liaw, Andy, Wang, Shubing, Stout, Steven J., Keohan, CarolAnn, Forrest, Gail, Coelho, David, Yendluri, Satya, Williams, Stephanie, Koser, Martin, Bartz, Steven, Akinsanya, Karen O., Pinto, Shirly

“…SREBP cleavage-activating protein (SCAP) is a key protein in the regulation of lipid metabolism and a potential target for treatment of dyslipidemia. SCAP is…”
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Novel Immunocompetent Murine Tumor Model for Evaluation of Conditionally Replication-Competent (Oncolytic) Murine Adenoviral Vectors by ROBINSON, Michael, LI, Betty, YING GE, KO, Derek, YENDLURI, Satya, HARDING, Thomas, VANROEY, Melinda, SPINDLER, Katherine R, JOOSS, Karin

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Enhanced gene transfer efficiency in the murine striatum and an orthotopic glioblastoma tumor model, using AAV-7- and AAV-8-pseudotyped vectors by Harding, Thomas C, Dickinson, Peter J, Roberts, Byron N, Yendluri, Satya, Gonzalez-Edick, Melissa, Lecouteur, Richard A, Jooss, Karin U

“…In this study, recombinant AAV vectors pseudotyped with viral capsids derived from AAV serotypes 7 and 8 were evaluated for gene transfer in the murine…”
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Antiviral Nucleotide Incorporation by Recombinant Human Mitochondrial RNA Polymerase Is Predictive of Increased In Vivo Mitochondrial Toxicity Risk by Fenaux, Martijn, Lin, Xiaodong, Yokokawa, Fumiaki, Sweeney, Zachary, Saunders, Oliver, Xie, Lili, Lim, Siew Pheng, Uteng, Marianne, Uehara, Kyoko, Warne, Robert, Gang, Wang, Jones, Christopher, Yendluri, Satya, Gu, Helen, Mansfield, Keith, Boisclair, Julie, Heimbach, Tycho, Catoire, Alexandre, Bracken, Kathryn, Weaver, Margaret, Moser, Heinz, Zhong, Weidong

“…Nucleoside or nucleotide inhibitors are a highly successful class of antivirals due to selectivity, potency, broad coverage, and high barrier to resistance…”
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Development of Lipoprotein(a) siRNAs for Mechanism of Action Studies in Non-Human Primate Models of Atherosclerosis by Tadin-Strapps, Marija, Robinson, Michael, Le Voci, Lauretta, Andrews, Lori, Yendluri, Satya, Williams, Stephanie, Bartz, Steve, Johns, Douglas G.

“…Lipoprotein(a) [Lp(a)] has recently been recognized as an independent risk factor for coronary heart disease. While plasma Lp(a) levels are correlated with…”
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Abstract B261: Characterization of FASN-selective small-molecule inhibitors in preclinical tumor models by Heuer, Timothy S., Chen, Minchao, Ventura, Richard, Waszczuk, Joanna, Yendluri, Satya, Lai, Julie, Tep, Samnang, Feng, Shirley, Johnson, Russell, Zaharia, Cristiana, Buckley, Douglas, Kemble, George

“…The purpose of this study is to characterize the activity of small-molecule FASN inhibitors in preclinical models of human cancer to evaluate their potential…”
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130. Insertion of Transgenes into the E3 or L3 Region To Allow Tumor Selective Expression from Armed Oncolytic Adenoviruses by Robinson, Michael, Yendluri, Satya, Ko, Derek, Hawkins, Lynda, Jooss, Karin

“…The ability to arm oncolytic vectors with transgenes gives researchers a mechanism for potential improvements in the vector potency. However, depending on the…”
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Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy by Dishart, Kate L, Denby, Laura, George, Sarah J, Nicklin, Stuart A, Yendluri, Satya, Tuerk, Melanie J, Kelley, Michael P, Donahue, Brian A, Newby, Andrew C, Harding, Thomas, Baker, Andrew H

“…Grafting of saphenous vein (SV) conduits into the arterial circulation triggers a number of adaptive pathological changes characterized by progressive medial…”
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AAV Serotype 8-Mediated Gene Delivery of a Soluble VEGF Receptor to the CNS for the Treatment of Glioblastoma by Harding, Thomas C., Lalani, Alshad S., Roberts, Byron N., Yendluri, Satya, Luan, Bo, Koprivnikar, Kathryn E., Gonzalez-Edick, Melissa, Huan-Tu, Guang, Musterer, Randy, VanRoey, Melinda J., Ozawa, Tomoko, LeCouter, Richard A., Deen, Dennis, Dickinson, Peter J., Jooss, Karin

“…The presence of the blood–brain barrier complicates drug delivery in the development of therapeutic agents for the treatment of glioblastoma multiforme (GBM)…”
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974. Adeno-Associated Viral (AAV)-Mediated Gene Transfer of Soluble Vascular Endothelial Growth Factor Receptor 3 (sVEGFR3) Inhibits Development of Lymph Node Metastases by Lin, Jian-min, Lalani, Alshad S, Harding, Thomas, Wu, Weiwei, Luan, Bo, Yendluri, Satya, Vanroey, Melinda J, He, Yulong, Alitalo, Kari, Jooss, Karin

“…The metastatic spread of tumor cells represents a critical point in tumor progression. The presence of metastases in regional lymph nodes is a strong indicator…”
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