Search Results - The Korean Society for Brain and Neural Sciences

Development of a Laboratory-safe and Low-cost Detection Protocol for SARS-CoV-2 of the Coronavirus Disease 2019 (COVID-19) by Won, Joungha, Lee, Solji, Park, Myungsun, Kim, Tai Young, Park, Mingu Gordon, Choi, Byung Yoon, Kim, Dongwan, Chang, Hyeshik, Kim, V Narry, Lee, C Justin

“…The severe acute respiratory coronavirus 2 (SARS-CoV-2), which emerged in December 2019 in Wuhan, China, has spread rapidly to over a dozen countries…”
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Cholesterol Metabolism in the Brain and Its Association with Parkinson’s Disease by Jin, Uram, Park, Soo Jin, Park, Sang Myun

“…Parkinson’s disease (PD) is the second most progressive neurodegenerative disorder of the aging population after Alzheimer’s disease (AD). Defects in the…”
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Autophagy, Cellular Aging and Age-related Human Diseases by Cheon, So Yeong, Kim, Hyunjeong, Rubinsztein, David C, Lee, Jong Eun

“…Macroautophagy/autophagy is a conserved degradation system that engulfs intracytoplasmic contents, including aggregated proteins and organelles, which is…”
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Physiological Roles of Monomeric Amyloid-β and Implications for Alzheimer's Disease Therapeutics by Jeong, Hyomin, Shin, Heewon, Hong, Seungpyo, Kim, YoungSoo

“…Alzheimer's disease (AD) progressively inflicts impairment of synaptic functions with notable deposition of amyloid-β (Aβ) as senile plaques within the…”
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Bidirectional Control of Emotional Behaviors by Excitatory and Inhibitory Neurons in the Orbitofrontal Cortex by Kim, Jihoon, Choi, Mijung, Lee, Jimin, Park, Inah, Kim, Kyungjin, Choe, Han Kyoung

“…The orbitofrontal cortex (OFC) plays a crucial role in mood disorders; however, its specific role in the emotional behaviors of mice remains unclear. This…”
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β-PIX-d, a Member of the ARHGEF7 Guanine Nucleotide Exchange Factor Family, Activates Rac1 and Induces Neuritogenesis in Primary Cortical Neurons by Kim, Seunghyuk, Park, Heeyoung, Kang, Jieun, Choi, Seunghyuk, Sadra, Ali, Huh, Sung-Oh

“…β-PIX, a Rac1/Cdc42-specific guanine nucleotide exchange factor, is known to regulate actin cytoskeleton remodeling during cell migration. In this study, we…”
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Systemic Inflammation Decreases Initial Brain Injury but Attenuates Neurite Extension and Synapse Formation during the Repair of Injured Brains by Gaire, Sushil, Yang, Haijie, Dumre, Manisha, Lee, Eun Jeong, Park, Sang-Myun, Joe, Eun-Hye

“…In this study, we explored the impact of systemic inflammation on initial brain injury and repair processes, including neurite extension and synapse formation…”
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The Impact of Odor Category Similarity on Multimedia Experience by Kim, Kwangsu, Bae, Jisub, Lee, JeeWon, Moon, Sun Ae, Lee, Sang-Ho, Kang, Won-Seok, Moon, Cheil

“…Although we have multiple senses, multimedia mainly targets vision and olfaction. To expand the senses impacted by multimedia, olfactory stimulation has been…”
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Impaired Cholesterol Metabolism, Neurons, and Neuropsychiatric Disorders by Cheon, So Yeong

“…Cholesterol metabolism plays an essential role in cellular functions (including as a component of the plasma membrane, as an energy source, and in hormone…”
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Attentional Connectivity-based Prediction of Autism Using Heterogeneous rs-fMRI Data from CC200 Atlas by Liu, Yaya, Xu, Lingyu, Li, Jun, Yu, Jie, Yu, Xuan

“…Autism spectrum disorder (ASD) is a developmental syndrome characterized by obvious drawbacks in sociality and communication. It has crucial significance to…”
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Long Noncoding RNA PVT1 Promotes Stemness and Temozolomide Resistance through miR-365/ELF4/SOX2 Axis in Glioma by Gong, Rui, Li, Zhi-Qiang, Fu, Kai, Ma, Chao, Wang, Wei, Chen, Jin-Cao

“…Long non-coding RNA (lncRNA) are a class of non-coding RNAs demonstrated to play pivotal roles in regulating tumor progression. Therefore, deciphering the…”
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Overexpression of SIRT3 Suppresses Oxidative Stress-induced Neurotoxicity and Mitochondrial Dysfunction in Dopaminergic Neuronal Cells by Lee, Shinrye, Jeon, Yu-Mi, Jo, Myungjin, Kim, Hyung-Jun

“…Sirtuin 3 (SIRT3), a well-known mitochondrial deacetylase, is involved in mitochondrial function and metabolism under various stress conditions. In this study,…”
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3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABAA-benzodiazepine Receptors by Woo, Junsung, Yang, Hyejin, Yoon, Minseok, Gadhe, Changdev G, Pae, Ae Nim, Cho, Suengmok, Lee, C Justin

“…3-Carene, a bicyclic monoterpene, is one of the major components of the pine tree essential oils. It has been reported that, in addition to its known…”
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Urinary Biomarkers for Neurodegenerative Diseases by Seol, Wongi, Kim, Hyejung, Son, Ilhong

“…Global incidence of neurodegenerative diseases (NDDs) such as Alzheimer's disease (AD) and Parkinson's disease (PD) is rapidly increasing, but the diagnosis of…”
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Advances in Amyloid-β Clearance in the Brain and Periphery: Implications for Neurodegenerative Diseases by Ullah, Rahat, Lee, Eun Jeong

“…This review examines the role of impaired amyloid-β clearance in the accumulation of amyloid-β in the brain and the periphery, which is closely associated with…”
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Astrocyte-targeted Overproduction of IL-10 Reduces Neurodegeneration after TBI by Shanaki-Bavarsad, Mahsa, Almolda, Beatriz, González, Berta, Castellano, Bernardo

“…Traumatic brain injury is the greatest cause of disability and death in young adults in the developed world. The outcome for a TBI patient is determined by the…”
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Generation of Astrocyte-specific BEST1 Conditional Knockout Mouse with Reduced Tonic GABA Inhibition in the Brain by Joo, Jinhyeong, Kim, Ki Jung, Lim, Jiwoon, Choi, Sun Yeong, Koh, Wuhyun, Lee, C Justin

“…Bestrophin-1 (BEST1) is a Ca -activated anion channel known for its role in astrocytes. Best1 is permeable to gliotransmitters, including GABA, to contribute…”
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Nobiletin Exhibits Neuroprotective Effects against Mitochondrial Complex I Inhibition via Regulating Apoptotic Signaling by Amarsanaa, Khulan, Kim, Hye-Ji, Ko, Eun-A, Jo, Jaemin, Jung, Sung-Cherl

“…Nobiletin, a polymethoxylated flavonoid found in citrus, has been studied because of its modulatory functions in cellular signaling cascades, and effects to…”
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HDAC Inhibition by Valproic Acid Induces Neuroprotection and Improvement of PD-like Behaviors in LRRK2 R1441G Transgenic Mice by Kim, Taewoo, Song, Seohoe, Park, Yeongwon, Kang, Sinil, Seo, Hyemyung

“…Parkinson's disease (PD) is one of the late-onset neurodegenerative movement disorder. Major pathological markers of PD include progressive loss of…”
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Sleep-enhancing Effects of Phytoncide Via Behavioral, Electrophysiological, and Molecular Modeling Approaches by Woo, Junsung, Lee, C Justin

“…Sleep is indispensable for living animals to live and maintain a normal life. Due to the growing number of people suffering from sleep disorders such as…”
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