Search Results - Stephan Gruber

Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes by Palecek, Jan J., Gruber, Stephan

“…SMC/kleisin complexes form elongated annular structures, which are critical for chromosome segregation, genome maintenance, and the regulation of gene…”
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DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes by Marko, John F, De Los Rios, Paolo, Barducci, Alessandro, Gruber, Stephan

“…Cells possess remarkable control of the folding and entanglement topology of long and flexible chromosomal DNA molecules. It is thought that structural…”
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Ground subsidence and heave over permafrost: hourly time series reveal interannual, seasonal and shorter-term movement caused by freezing, thawing and water movement by Gruber, Stephan

“…Heave and subsidence of the ground surface can offer insight into processes of heat and mass transfer in freezing and thawing soils. Additionally, subsidence…”
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Recruitment of Condensin to Replication Origin Regions by ParB/SpoOJ Promotes Chromosome Segregation in B. subtilis by Gruber, Stephan, Errington, Jeff

“…Proper segregation of DNA replication products is essential in all cells. In Bacillus subtilis, two protein complexes have been implicated in this process: the…”
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DNA tension-modulated translocation and loop extrusion by SMC complexes revealed by molecular dynamics simulations by Nomidis, Stefanos K, Carlon, Enrico, Gruber, Stephan, Marko, John F

“…Structural Maintenance of Chromosomes (SMC) complexes play essential roles in genome organization across all domains of life. To determine how the activities…”
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Multilayer chromosome organization through DNA bending, bridging and extrusion by Gruber, Stephan

“…Highlights • Bacterial nucleoids are compact, dynamic and highly organized structures. • Abundant DNA bending proteins cause local folding of chromosomal DNA…”
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Environmental controls of frost cracking revealed through in situ acoustic emission measurements in steep bedrock by Girard, Lucas, Gruber, Stephan, Weber, Samuel, Beutel, Jan

“…Frost cracking, the breakdown of rock by freezing, is one of the most important mechanical weathering processes acting on Earth's surface. Insights on the…”
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Permafrost in steep bedrock slopes and its temperature-related destabilization following climate change by Gruber, S., Haeberli, W.

“…Permafrost in steep bedrock is abundant in many cold‐mountain areas, and its degradation can cause slope instability that is unexpected and unprecedented in…”
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Kinematics of steep bedrock permafrost by Hasler, Andreas, Gruber, Stephan, Beutel, Jan

“…The mechanisms that control climate‐dependent rockfall from permafrost mountain slopes are currently poorly understood. In this study, we present the results…”
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Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells by Tišma, Miloš, Bock, Florian Patrick, Kerssemakers, Jacob, Antar, Hammam, Japaridze, Aleksandre, Gruber, Stephan, Dekker, Cees

“…Bacterial chromosomes are folded into tightly regulated three-dimensional structures to ensure proper transcription, replication, and segregation of the…”
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Author Correction: Direct observation of a crescent-shape chromosome in expanded Bacillus subtilis cells by Tišma, Miloš, Bock, Florian Patrick, Kerssemakers, Jacob, Antar, Hammam, Japaridze, Aleksandre, Gruber, Stephan, Dekker, Cees

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A low Smc flux avoids collisions and facilitates chromosome organization in Bacillus subtilis by Anchimiuk, Anna, Lioy, Virginia S, Bock, Florian Patrick, Minnen, Anita, Boccard, Frederic, Gruber, Stephan

“…SMC complexes are widely conserved ATP-powered DNA-loop-extrusion motors indispensable for organizing and faithfully segregating chromosomes. How SMC complexes…”
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SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis by Wilhelm, Larissa, Bürmann, Frank, Minnen, Anita, Shin, Ho-Chul, Toseland, Christopher P, Oh, Byung-Ha, Gruber, Stephan

“…Smc-ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic…”
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SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae by Minnen, Anita, Attaiech, Laetitia, Thon, Maria, Gruber, Stephan, Veening, Jan‐Willem

“…Summary Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval‐shaped human pathogen Streptococcus…”
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Permafrost thaw and destabilization of Alpine rock walls in the hot summer of 2003 by Gruber, Stephan, Hoelzle, Martin, Haeberli, Wilfried

“…Exceptional rockfall occurred throughout the Alps during the unusually hot summer of 2003. It is likely related to the fast thermal reaction of the subsurface…”
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Design analysis of a hybrid storage concept combining Ruths steam storage and latent thermal energy storage by Dusek, Sabrina, Hofmann, René, Gruber, Stephan

“…[Display omitted] •New hybrid thermal energy storage concept for storing steam and electrical energy.•Analysis by variation of number and properties of…”
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Control of Smc Coiled Coil Architecture by the ATPase Heads Facilitates Targeting to Chromosomal ParB/parS and Release onto Flanking DNA by Minnen, Anita, Bürmann, Frank, Wilhelm, Larissa, Anchimiuk, Anna, Diebold-Durand, Marie-Laure, Gruber, Stephan

“…Smc/ScpAB promotes chromosome segregation in prokaryotes, presumably by compacting and resolving nascent sister chromosomes. The underlying mechanisms,…”
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A comparison of static and dynamic ∆B0 mapping methods for correction of CEST MRI in the presence of temporal B0 field variations by Poblador Rodriguez, Esau, Moser, Philipp, Dymerska, Barbara, Robinson, Simon, Schmitt, Benjamin, Kouwe, Andre, Gruber, Stephan, Trattnig, Siegfried, Bogner, Wolfgang

“…Purpose To assess the performance, in the presence of scanner instabilities, of three dynamic correction methods which integrate ∆B0 mapping into the chemical…”
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7T CEST MRI: A potential imaging tool for the assessment of tumor grade and cell proliferation in breast cancer by Zaric, Olgica, Farr, Alex, Poblador Rodriguez, Esau, Mlynarik, Vladimir, Bogner, Wolfgang, Gruber, Stephan, Asseryanis, Ella, Singer, Christian F., Trattnig, Siegfried

“…To investigate the feasibility of chemical exchange saturation transfer (CEST) MRI in patients with breast carcinomas and possible correlations between…”
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Improving permafrost physics in the coupled Canadian Land Surface Scheme (v.3.6.2) and Canadian Terrestrial Ecosystem Model (v.2.1) (CLASS-CTEM) by Melton, Joe R., Verseghy, Diana L., Sospedra-Alfonso, Reinel, Gruber, Stephan

“…The Canadian Land Surface Scheme and Canadian Terrestrial Ecosystem Model (CLASS-CTEM) together form the land surface component of the Canadian Earth System…”
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