Search Results - Seraphin, Joerg*

Second-Line Oxaliplatin, Folinic Acid, and Fluorouracil Versus Folinic Acid and Fluorouracil Alone for Gemcitabine-Refractory Pancreatic Cancer: Outcomes From the CONKO-003 Trial by OETTLE, Helmut, RIESS, Hanno, BISCHOFF, Sven, SINN, Marianne, DÖRKEN, Bernd, PELZER, Uwe, STIELER, Jens M, HEIL, Gerhard, SCHWANER, Ingo, SERAPHIN, Jörg, GÖRNER, Martin, MÖLLE, Matthias, GRETEN, Tim F, LAKNER, Volker

“…To assess the efficacy of a second-line regimen of oxaliplatin and folinic acid-modulated fluorouracil in patients with advanced pancreatic cancer who have…”
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Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: A phase III-study from the German CONKO-study group by Pelzer, Uwe, Schwaner, Ingo, Stieler, Jens, Adler, Mathias, Seraphin, Jörg, Dörken, Bernd, Riess, Hanno, Oettle, Helmut

“…Abstract Background Gemcitabine usually given until progressive disease (PD) is the main first-line treatment option for patients with inoperable advanced…”
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Phase III randomized, double‐blind study of paclitaxel with and without everolimus in patients with advanced gastric or esophagogastric junction carcinoma who have progressed after therapy with a fluoropyrimidine/platinum‐containing regimen (RADPAC) by Lorenzen, Sylvie, Knorrenschild, Jorge Riera, Pauligk, Claudia, Hegewisch‐Becker, Susanna, Seraphin, Jörg, Thuss‐Patience, Peter, Kopp, Hans‐Georg, Dechow, Tobias, Vogel, Arndt, Luley, Kim Barbara, Pink, Daniel, Stahl, Michael, Kullmann, Frank, Hebart, Holger, Siveke, Jens, Egger, Matthias, Homann, Nils, Probst, Stephan, Goetze, Thorsten Oliver, Al‐Batran, Salah‐Eddin

“…The RADPAC trial evaluated paclitaxel with everolimus in patients with advanced gastroesophageal cancer (GEC) who have progressed after therapy with a…”
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Bevacizumab in the first-line treatment of elderly patients with metastatic colorectal cancer: Mature results from a large community-based observational study by Hofheinz, Ralf, Grothe, Wilfried, Tummes, Dirk, Kindler, Manfred, Petersen, Volker, Boszeit-Luft, Stefanie, Seraphin, Joerg, Hinke, Axel, Arnold, Dirk

“…Abstract only 566 Background: In most patients (pts) with metastatic colorectal cancer, a 3-drug combination of a fluoropyrimidine, oxaliplatin (ox) or…”
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Prognostic factors for long-term overall survival (OS) for patients (pts) undergoing first-line treatment for metastatic colorectal cancer (mCRC) with chemotherapy (CT) plus bevacizumab (bev): Findings from a large observational study by Arnold, Dirk, Grothe, Wilfried, Tummes, Dirk, Kindler, Manfred, Petersen, Volker, Boszeit-Luft, Stefanie, Seraphin, Joerg, Kutscheidt, Andreas

“…Abstract only 590 Background: Bev+CT has been shown to improve OS vs. CT alone in phase III and IV mCRC studies. However, as only a subset of pts experience OS…”
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Bevacizumab in first-line treatment of elderly patients with metastatic colorectal cancer: German community-based observational cohort study results by Hofheinz, Ralf, Petersen, Volker, Kindler, Manfred, Schulze, Mathias, Seraphin, Joerg, Hoeffkes, Heinz-Gert, Valdix, Anette-R, Schroeder, Jan, Herrenberger, Julia, Stein, Alexander, Hinke, Axel, Arnold, Dirk

“…To evaluate the efficacy of first-line bevacizumab-based chemotherapy for untreated metastatic colorectal cancer (mCRC) based on age. Eligibility criteria…”
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Baseline and On-Treatment Markers Determining Prognosis of First-Line Chemotherapy in Combination with Bevacizumab in Patients with Metastatic Colorectal Cancer by Quidde, Julia, Denne, Laura, Kutscheidt, Andreas, Kindler, Manfred, Kirsch, Andreas, Kripp, Melanie, Petersen, Volker, Schulze, Matthias, Seraphin, Jörg, Tummes, Dirk, Arnold, Dirk, Stein, Alexander

“…In metastatic colorectal cancer, no upfront or on-treatment markers are available to determine the prognosis or efficacy for chemotherapy in combination with…”
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Molecular cytogenetic monitoring from CD34+ peripheral blood cells in myelodysplastic syndromes: First results from a prospective multicenter German diagnostic study by Braulke, Friederike, Jung, Klaus, Schanz, Julie, Götze, Katharina, Müller-Thomas, Catharina, Platzbecker, Uwe, Germing, Ulrich, Brümmendorf, Tim H, Bug, Gesine, Ottmann, Oliver, Giagounidis, Aristoteles A.N, Stadler, Michael, Hofmann, Wolf-Karsten, Schafhausen, Philippe, Lübbert, Michael, Schlenk, Richard F, Blau, Igor W, Ganster, Christina, Pfeiffer, Sebastian, Shirneshan, Katayoon, Metz, Michael, Detken, Sven, Seraphin, Jörg, Jentsch-Ullrich, Kathleen, Böhme, Angelika, Schmidt, Burkhard, Trümper, Lorenz, Haase, Detlef

“…Abstract The gold standard of cytogenetic analysis in myelodysplastic syndromes (MDS) is conventional chromosome banding (CCB) analysis of bone marrow (BM)…”
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Detection of Karyotype Evolution From Peripheral Blood by Sequential FISH Analyses of Circulating CD34+ Cells In MDS Patients: Results of the Ongoing German Multicenter Prospective Diagnostic Study by Braulke, Friederike, Schanz, Julie, Metz, Michael, Detken, Sven, Seraphin, Joerg, Götze, Katharina, Mueller-Thomas, Catharina, Platzbecker, Uwe, Brümmendorf, Tim Henrik, Giagounidis, Aristoteles A.N., Germing, Ulrich, Jentsch-Ullrich, Kathleen, Boehme, Angelika, Bug, Gesine, Ottmann, Oliver G., Schafhausen, Philippe, Trümper, Lorenz, Haase, Detlef

“…Abstract 2937 Chromosomal aberrations in myelodysplastic syndromes (MDS) play a major role in diagnostics, pathogenesis, prognosis, and, more recently, in…”
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Rapid Selection of Sotrovimab Escape Variants in Severe Acute Respiratory Syndrome Coronavirus 2 Omicron-Infected Immunocompromised Patients by Gliga, Smaranda, Lübke, Nadine, Killer, Alexander, Gruell, Henning, Walker, Andreas, Dilthey, Alexander T, Thielen, Alexander, Lohr, Carolin, Flaßhove, Charlotte, Krieg, Sarah, Pereira, Joanna Ventura, Seraphin, Tobias Paul, Zaufel, Alex, Däumer, Martin, Orth, Hans-Martin, Feldt, Torsten, Bode, Johannes G, Klein, Florian, Timm, Jörg, Luedde, Tom, Jensen, Björn-Erik Ole

“…Abstract Background Monoclonal antibodies (mAbs) that target severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are predominantly less effective…”
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Clinical presentation and diagnosis of adult patients with non‐Hodgkin lymphoma in Sub‐Saharan Africa by Mezger, Nikolaus C. S., Feuchtner, Jana, Griesel, Mirko, Hämmerl, Lucia, Seraphin, Tobias P., Zietsman, Annelle, Péko, Jean‐Félix, Tadesse, Fisihatsion, Buziba, Nathan G., Wabinga, Henry, Nyanchama, Mary, Borok, Margaret Z., Kéita, Mamadou, N'da, Guy, Lorenzoni, Cesaltina F., Akele‐Akpo, Marie‐Thérèse, Gottschick, Cornelia, Binder, Mascha, Mezger, Jörg, Jemal, Ahmedin, Parkin, Donald M., Wickenhauser, Claudia, Kantelhardt, Eva J.

“…Summary Non‐Hodgkin lymphoma (NHL) is the sixth most common cancer in Sub‐Saharan Africa (SSA). Comprehensive diagnostics of NHL are essential for effective…”
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Guideline Concordance of Treatment and Outcomes Among Adult Non-Hodgkin Lymphoma Patients in Sub-Saharan Africa: A Multinational, Population-Based Cohort by Mezger, Nikolaus Christian Simon, Hämmerl, Lucia, Griesel, Mirko, Seraphin, Tobias Paul, Joko-Fru, Yvonne Walburga, Feuchtner, Jana, Zietsman, Annelle, Péko, Jean-Félix, Tadesse, Fisihatsion, Buziba, Nathan Gyabi, Wabinga, Henry, Nyanchama, Mary, Chokunonga, Eric, Kéita, Mamadou, N’da, Guy, Lorenzoni, Cesaltina Ferreira, Akele-Akpo, Marie-Thérèse, Mezger, Jörg Michael, Binder, Mascha, Liu, Biying, Bauer, Marcus, Henke, Oliver, Jemal, Ahmedin, Kantelhardt, Eva Johanna

“…Abstract Background Although non-Hodgkin lymphoma (NHL) is the 6th most common malignancy in Sub-Saharan Africa (SSA), little is known about its management and…”
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