Search Results - Scholl, Suzy

RAIDS atlas of significant genetic and protein biomarkers in cervical cancer by Scholl, Suzy, Roufai, Diana Bello, Chérif, Linda Larbi, Kamal, Maud

“…Loss of function in epigenetic acting genes together with driver alterations in the PIK3CA pathway have been shown significantly associated with poor outcome…”
Get full text

Therapeutic vaccines for cancer: an overview of clinical trials by Melero, Ignacio, Gaudernack, Gustav, Gerritsen, Winald, Huber, Christoph, Parmiani, Giorgio, Scholl, Suzy, Thatcher, Nicholas, Wagstaff, John, Zielinski, Christoph, Faulkner, Ian, Mellstedt, Håkan

“…Key Points Development of vaccines for the treatment of cancer has posed many challenges, but results from some recent studies have confirmed the potential for…”
Get full text

Systematic assessment of tumor necrosis at baseline in cervical cancer - An independent factor associated with poor outcome by Chouchane-Mlik, Olfa, Oniga, Alexandra, Latouche, Aurélien, Halladjian, Maral, Kleine-Borgmann, Felix B, Gérardy, Jean-Jacques, Mittelbronn, Michel, Kamal, Maud, Scholl, Suzy M

“…Cervical cancer (CC) is a leading challenge in oncology worldwide, with high prevalence and mortality rates in young adults, most prominent in low to…”
Get full text

Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site by Kamal, Maud, Lameiras, Sonia, Deloger, Marc, Morel, Adeline, Vacher, Sophie, Lecerf, Charlotte, Dupain, Célia, Jeannot, Emmanuelle, Girard, Elodie, Baulande, Sylvain, Dubot, Coraline, Kenter, Gemma, Jordanova, Ekaterina S., Berns, Els M. J. J., Bataillon, Guillaume, Popovic, Marina, Rouzier, Roman, Cacheux, Wulfran, Le Tourneau, Christophe, Nicolas, Alain, Servant, Nicolas, Scholl, Suzy M., Bièche, Ivan

“…Background Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality with infection by human papilloma virus (HPV) being the most…”
Get full text

HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia by Samuels, Sanne, Marijne Heeren, A., Zijlmans, Henry J. M. A. A., Welters, Marij J. P., van den Berg, Joost H., Philips, Daisy, Kvistborg, Pia, Ehsan, Ilina, Scholl, Suzy M. E., Nuijen, Bastiaan, Schumacher, Ton N. M., van Beurden, Marc, Jordanova, Ekaterina S., Haanen, John B. A. G., van der Burg, Sjoerd H., Kenter, Gemma G.

“…Background Usual type vulvar intraepithelial neoplasia (uVIN) is caused by HPV, predominantly type 16. Several forms of HPV immunotherapy have been studied,…”
Get full text

High Numbers of Differentiated Effector CD4 T Cells Are Found in Patients with Cancer and Correlate with Clinical Response after Neoadjuvant Therapy of Breast Cancer by PEGUILLET, Isabelle, MILDER, Maud, LOUIS, Delphine, VINCENT-SALOMON, Anne, DORVAL, Thierry, PIPERNO-NEUMANN, Sophie, SCHOLL, Suzy M, LANTZ, Olivier

“…CD4(+) T cells influence tumor immunity in complex ways that are not fully understood. In this study, we characterized a population of human differentiated…”
Get full text

PIK3CA Pathway Mutations Predictive of Poor Response Following Standard Radiochemotherapy ± Cetuximab in Cervical Cancer Patients by de la Rochefordiere, Anne, Kamal, Maud, Floquet, Anne, Thomas, Laurence, Petrow, Peter, Petit, Thierry, Pop, Marius, Fabbro, Michel, Kerr, Christine, Joly, Florence, Sevin, Emmanuel, Maillard, Sophie, Curé, Hervé, Weber, Béatrice, Brunaud, Claire, Minsat, Mathieu, Gonzague, Laurence, Berton-Rigaud, Dominique, Aumont, Maud, Gladieff, Laurence, Peignaux, Karine, Bernard, Virginie, Leroy, Quentin, Bieche, Ivan, Margogne, Audrey, Nadan, AnaTereza, Fourchotte, Virginie, Diallo, Alhassane, Asselain, Benard, Plancher, Corine, Armanet, Sébastien, Beuzeboc, Philippe, Scholl, Suzy M

“…EGFR is frequently overexpressed in cervical cancer, suggesting EGFR blockade as a promising treatment approach. Cetuximab, an anti EGFR antibody, used…”
Get full text

Recommendations From an International Expert Panel on the Use of Neoadjuvant (Primary) Systemic Treatment of Operable Breast Cancer: An Update by Kaufmann, Manfred, Hortobagyi, Gabriel N, Goldhirsch, Aron, Scholl, Suzy, Makris, Andreas, Valagussa, Pinuccia, Blohmer, Jens-Uwe, Eiermann, Wolfgang, Jackesz, Raimund, Jonat, Walter, Lebeau, Annette, Loibl, Sibylle, Miller, William, Seeber, Sigfried, Semiglazov, Vladimir, Smith, Roy, Souchon, Rainer, Stearns, Vered, Untch, Michael, von Minckwitz, Gunter

“…Neoadjuvant (primary systemic) treatment is the standard treatment for locally advanced breast cancer and a standard option for primary operable disease…”
Get full text

Fundamental Principles of Raising an Antitumour Immune Response in Vivo: A Complex Model, a Case Report, and a Perspective by Scholl, Suzy M.

“…In preclinical model systems, the fundamental principles underlying a successful and durable anti-tumour immune response are well demonstrated. In clinical…”
Get full text

Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer by Scholl, Suzy M, Beal, Jonas, de Koning, Leanne, Girard, Elodie, Popovic, Marina, de la Rochefordière, Anne, Lecuru, Fabrice, Fourchotte, Virginie, Ngo, Charlotte, Floquet, Anne, Berns, Els MJJ, Kenter, Gemma, Gestraud, Pierre, von der Leyen, Heiko, Lecerf, Charlotte, Puard, Vincent, Roman, Sergio Roman, Latouche, Aurelien, Kereszt, Attila, Balint, Balazs, Rouzier, Roman, Kamal, Maud

“…Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality world wide and constitutes the third most common malignancy in women…”
Get full text

Regression of high-grade cervical intraepithelial neoplasia with TG4001 targeted immunotherapy by Brun, Jean-Luc, MD, Dalstein, Véronique, PhD, Leveque, Jean, MD, PhD, Mathevet, Patrice, MD, PhD, Raulic, Patrick, MD, Baldauf, Jean-Jacques, MD, Scholl, Suzy, MD, Huynh, Bernard, MD, Douvier, Serge, MD, PhD, Riethmuller, Didier, MD, PhD, Clavel, Christine, PhD, Birembaut, Philippe, MD, PhD, Calenda, Valérie, PhD, Baudin, Martine, MD, PhD, Bory, Jean-Paul, MD

“…Objective We sought to evaluate the safety and efficacy of TG4001 in patients with human papillomavirus (HPV) 16–related cervical intraepithelial neoplasia…”
Get full text

Advances and Concepts in Cervical Cancer Trials: A Road Map for the Future by Sagae, Satoru, Monk, Bradley J, Pujade-Lauraine, Eric, Gaffney, David K, Narayan, Kailash, Ryu, Sang Young, McCormack, Mary, Plante, Marie, Casado, Antonio, Reuss, Alexander, Chávez-Blanco, Adriana, Kitchener, Henry, Nam, Byung-Ho, Jhingran, Anuja, Temkin, Sarah, Mileshkin, Linda, Berns, Els, Scholl, Suzy, Doll, Corinne, Abu-Rustum, Nadeem R, Lecuru, Fabrice, Small, Jr, William

“…Cervical cancer is responsible for more than a quarter of a million deaths globally each year, mostly in developing countries, making therapeutic advances in…”
Get more information

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization by Vallerand, David, Massonnet, Gérald, Kébir, Fatima, Gentien, David, Maciorowski, Zofia, De la Grange, Pierre, Sigal-Zafrani, Brigitte, Richardson, Marion, Humbert, Sandrine, Thuleau, Aurélie, Assayag, Franck, de Plater, Ludmilla, Nicolas, André, Scholl, Suzy, Marangoni, Elisabetta, Weigand, Stefan, Roman-Roman, Sergio, Savina, Ariel, Decaudin, Didier

“…Drug discovery efforts have focused on the tumor microenvironment in recent years. However, few studies have characterized the stroma component in…”
Get full text

Corrigendum to ‘clinical and genetic landscape of treatment naive cervical cancer: Alterations in PIK3CA and in epigenetic modulators associated with sub-optimal outcome’ by Scholl, Suzy, Popovic, Marina, Rochefordiere, Anne de la, Girard, Elodie, Dureau, Sylvain, Mandic, Aljosa, Koprivsek, Katarina, Samet, Nina, Craina, Marius, Margan, Madalin, Samuels, Sanne, Zijlmans, Henry, Kenter, Gemma, Hillemanns, Peter, Dema, Sorin, Dema, Alis, Malenkovic, Goran, Djuran, Branislav, Floquet, Anne, Garbay, Delphine, Guyon, Frédéric, Colombo, Pierre Emmanuel, Fabbro, Michel, Kerr, Christine, Ngo, Charlotte, Lecuru, Fabrice, del Campo, Eleonor Rivin, Coutant, Charles, Marchal, Frédéric, Mesgouez-Nebout, Nathalie, Fourchotte, Virginie, Feron, Jean Guillaume, Morice, Philippe, Deutsch, Eric, Wimberger, Pauline, Classe, Jean-Marc, Gleeson, Noreen, Leyen, Heiko von der, Minsat, Mathieu, Dubot, Coraline, Gestraud, Pierre, Kereszt, Attila, Nagy, Istvan, Balint, Balazs, Berns, Els, Jordanova, Ekaterina, de Saint-Jorre, Nicolas, Savignoni, Alexia, Servant, Nicolas, Hupe, Philippe, de Koning, Leanne, Fumoleau, Pierre, Rouzier, Roman, Kamal, Maud

Get full text

Gynecological Cancers Translational, Research Implementation, and Harmonization: Gynecologic Cancer InterGroup Consensus and Still Open Questions by Bagnoli, Marina, Shi, Ting Yan, Gourley, Charlie, Speiser, Paul, Reuss, Alexander, Nijman, Hans W, Creutzberg, Carien L, Scholl, Suzy, Negrouk, Anastassia, Brady, Mark F, Hasegawa, Kosei, Oda, Katsutoshi, McNeish, Iain A, Kohn, Elise C, Oza, Amit M, MacKay, Helen, Millan, David, Bennett, Katherine, Scott, Clare, Mezzanzanica, Delia

“…In the era of personalized medicine, the introduction of translational studies in clinical trials has substantially increased their costs, but provides the…”
Get full text

Abstract 5664: Genetic alterations and pharmacological response profiles from 10 cervical cancer cell lines by Scholl, Suzy, Gestraud, Pierre, Girard, Elodie, Lecompte, Lolita, Halladjian, Maral, de Koning, Leanne, Servant, Nicolas, Kamal, Maud, Nery, Elaine Del

“…Abstract Background: There are significant parallels between CC cell lines (CCCL) and newly diagnosed tumors, the most prominent being HPV…”
Get full text

Abstract 1755: Integrative genomic and transcriptomic profiles from a prospective cervical cancer study (RAIDs) by Kamal, Maud, Barraud, Solenn, Lecompte, Lolita, Halladjian, Maral, Jeannot, Emmanuelle, Girard, Elodie, Baulande, Sylvain, Legoix, Patricia, Lecuru, Fabrice, Pauly, Léa, Saint-Ghislain, Mathilde, Cyrille, Stacy, Dupain, Célia, Lamy, Constance, Chouchane-Mlik, Olfa, Oniga, Alexandra, Mittelbronn, Michel, Tourneau, Christophe Le, Latouche, Aurélien, Servant, Nicolas, Scholl, Suzy, Bièche, Ivan

“…Abstract Background: Cervical cancer (CC) remains a leading cause of gynecological cancer related mortality worldwide and constitutes the third most common…”
Get full text

From prospective biobanking to precision medicine: BIO-RAIDs - an EU study protocol in cervical cancer by Ngo, Charlotte, Samuels, Sanne, Bagrintseva, Ksenia, Slocker, Andrea, Hupé, Philippe, Kenter, Gemma, Popovic, Marina, Samet, Nina, Tresca, Patricia, von der Leyen, Heiko, Deutsch, Eric, Rouzier, Roman, Belin, Lisa, Kamal, Maud, Scholl, Suzy

“…Cervical cancer (CC) is -second to breast cancer- a dominant cause of gynecological cancer-related deaths worldwide. CC tumor biopsies and blood samples are of…”
Get full text

Assessment of the novel online delineation workshop dummy run approach using FALCON within a European multicentre trial in cervical cancer (RAIDs) by del Campo, Eleonor Rivin, Rivera, Sofia, Martínez-Paredes, María, Hupé, Philippe, Escarpa, Andrea Slocker, Borget, Isabelle, Mazeron, Renaud, Scholl, Suzy, Eito, Amalia Palacios, Haie-Meder, Christine, Chargari, Cyrus, Deutsch, Eric

“…Abstract Background and purpose Online delineation workshops (ODW) permit training of geographically dispersed participants. The purpose is to evaluate the…”
Get full text

Abstract 434: Rational molecular assessment and innovative drug selection (RAIDs): exome data from cervical cancer by Scholl, Suzy, Kamal, Maud, Berns, Els, Balint, Balzs, Kereszt, Attila, de Koning, Leanne, Jeannot, Emmanuelle, Luscap-rondof, Windy, Sibut, Vonick, Hupe, Philippe, Kenter, Gemma, Samuels, Sanne, Jordanova, Katja, Blanchet, Sandrine, Lafanachere, Laurence, Billaud, Marc

“…Abstract Background Recent retrospective data1,2 identified major molecular alterations in cervical cancer (CC), but so far there has been no prospective…”
Get full text