Search Results - Newlands Press Ltd

New horizons in lung cancer management through ATR/CHK1 pathway modulation by Thapa, Riya, Afzal, Obaid, Bhat, Asif Ahmad, Goyal, Ahsas, Alfawaz Altamimi, Abdulmalik Saleh, Almalki, Waleed Hassan, Alzarea, Sami I, Kazmi, Imran, Singh, Sachin Kumar, Dua, Kamal, Thangavelu, Lakshmi, Gupta, Gaurav

“…Lung cancer is the leading cause of cancer-related deaths worldwide. Molecular profiling has contributed to a new classification of lung cancer, driving…”
Get full text

Curcumin-based nanoformulations as an emerging therapeutic strategy for inflammatory lung diseases by Bhat, Asif Ahmad, Thapa, Riya, Goyal, Ahsas, Subramaniyan, Vetriselvan, Kumar, Deepak, Gupta, Saurabh, Singh, Sachin Kumar, Dua, Kamal, Gupta, Gaurav

Get full text

Flow cytometry: principles, applications and recent advances by Manohar, Sonal M, Shah, Prachi, Nair, Anusree

“…Flow cytometry (FCM) is a sophisticated technique that works on the principle of light scattering and fluorescence emission by the specific fluorescent…”
Get full text

N -heterocyclic carbene-metal complexes as bio-organometallic antimicrobial and anticancer drugs, an update (2015-2020) by A Patil, Siddappa, P Hoagland, Amy, A Patil, Shivaputra, Bugarin, Alejandro

“…-heterocyclic carbenes (NHCs) are organic compounds that typically mimic the chemical properties of phosphines. NHCs have made a significant impact on the…”
Get full text

Novel carbonic anhydrase inhibitors by Supuran, Claudiu T

Get full text

The role of microRNA-21 in the onset and progression of cancer by Singh, Ashutosh, Singh, Ashutosh Kumar, Giri, Rajanish, Kumar, Dhruv, Sharma, Rohit, Valis, Martin, Kuca, Kamil, Garg, Neha

“…MicroRNAs (miRNAs), a class of small noncoding RNA, posttranscriptionally regulate the expression of genes. Aberrant expression of miRNA is reported in various…”
Get full text

HeroMDAnalysis: an automagical tool for GROMACS-based molecular dynamics simulation analysis by Rawat, Ravi, Kant, Kamal, Kumar, Anoop, Bhati, Kajal, Verma, Saurabh M

“…Molecular dynamics simulations (MDS) using GROMACS are among the commonly used computational experiments in the area of molecular biology and drug discovery…”
Get full text

Exploring ACSL4/LPCAT3/ALOX15 and SLC7A11/GPX4/NFE2L2 as potential targets in ferroptosis-based cancer therapy by Gupta, Gaurav, Bhat, Asif Ahmad, Goyal, Ahsas, Singla, Neelam, Gupta, Saurabh, Sharma, Sanjay, Bhatt, Shvetank, Dua, Kamal

Get full text

Novel anthraquinone compounds as anticancer agents and their potential mechanism by Tian, Wei, Wang, Chunmiao, Li, Danrong, Hou, Huaxin

“…Anthraquinones exhibit a unique anticancer activity. Since their discovery, medicinal chemists have made several structural modifications, resulting in the…”
Get full text

PROTAC cell permeability and oral bioavailability: a journey into uncharted territory by Poongavanam, Vasanthanathan, Kihlberg, Jan

Get full text

Urea-functionalized organoselenium compounds as promising anti-HepG2 and apoptosis-inducing agents by El-Senduny, Fardous F, Shabana, Sameh M, Rösel, Daniel, Brabek, Jan, Althagafi, Ismail, Angeloni, Gregor, Manolikakes, Georg, Shaaban, Saad

“…Hepatocellular carcinoma is a highly aggressive and difficult-to-treat type of cancer. Incorporating urea functionality into the backbone of organoselenium…”
Get full text

2020 White Paper on Recent Issues in Bioanalysis: Vaccine Assay Validation, qPCR Assay Validation, QC for CAR-T Flow Cytometry, NAb Assay Harmonization and ELISpot Validation by Corsaro, Bart, Yang, Tong-yuan, Murphy, Rocio, Sonderegger, Ivo, Exley, Andrew, Bertholet, Sylvie, Dakappagari, Naveen, Dessy, Francis, Garofolo, Fabio, Kierstead, Lisa, Koch, Holger, Sarikonda, Ghanashyam, Savoie, Natasha, Siggers, Richard, Solstad, Therese, Lu, Yanmei, Milton, Mark, Marshall, Jean-Claude, DelCarpini, Jason, Gorovits, Boris, Gupta, Swati, Jesaitis, Lynne, Kamerud, John, Kromminga, Arno, Ma, Anna, McNally, Jim, Yan, Haoheng, Wu, Bonnie, Verthelyi, Daniela, Kirshner, Susan, Pedras-Vasconcelos, Joao, Rajadhyaksha, Manoj, Staack, Roland F., Cherry, Elana, Cludts, Isabelle, Dahlbäck, Madeleine, Gunn, George R., Ishii-Watabe, Akiko, Jawa, Vibha, Kubiak, Robert, Partridge, Michael, Petrillo, Marco, Pine, Samuel O., Poetzl, Johann, Song, Sam, Stebbins, Chris, Wu, Yuling, Zhang, Lucia, Kar, Sumit, Liang, Meina, Abhari, Mohsen Rajabi, Schweighardt, Becky, Stubenrauch, Kay, Xu, Yuanxin

“…The 14 edition of the Workshop on Recent Issues in Bioanalysis (14 WRIB) was held virtually on June 15-29, 2020 with an attendance of over 1000 representatives…”
Get full text

Antibacterial pyrazoles: tackling resistant bacteria by A Alam, Mohammad

“…Bacterial resistance to antibiotics threatens our progress in healthcare, modern medicine, food production and ultimately life expectancy. Antibiotic…”
Get full text

Novel N -bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, in vitro and in silico studies by El Azab, Islam H, Saied, Essa M, Osman, Alaa A, Mehana, Amir E, Saad, Hosam A, Elkanzi, Nadia Aa

“…Thiazole-substituted pyrazole is an important structural feature of many bioactive compounds, including antiviral, antitubercular, analgesic and anticancer…”
Get full text

The role of HGF/MET in liver cancer by Gupta, Gaurav, Al-Malki, Waleed Hassan, Kazmi, Imran, Thangavelu, Lakshmi, Gupta, Piyush Kumar, Jha, Niraj Kumar, Prasher, Parteek, Singh, Sachin Kumar, Dua, Kamal

Get full text

Kaempferol attenuates the effects of XIST/miR-130a/STAT3 on inflammation and extracellular matrix degradation in osteoarthritis by Xiao, Yaosheng, Liu, Lulin, Zheng, Yizhou, Liu, Wuyang, Xu, Youjia

“…To investigate whether kaempferol exhibited protective effects on osteoarthritis chondrocytes by modulating the XIST/miR-130a/STAT3 axis. qRT-PCR and western…”
Get full text

Pyrazole: an emerging privileged scaffold in drug discovery by Alam, Mohammad Abrar

“…Pyrazole or 1 -pyrazole, a five-membered 1,2-diazole, is found in several approved drugs and some bioactive natural products. A myriad number of derivatives of…”
Get full text

Identification of a novel antifungal backbone of naphthalimide thiazoles with synergistic potential for chemical and dynamic treatment by Zhang, Peng-Li, Lavanya, Gopala, Yu, Yang, Fang, Bo, Zhou, Cheng-He

“…The high incidence and prevalence of fungal infections call for new antifungal drugs. This work was to develop naphthalimide thiazoles as potential antifungal…”
Get full text

An overview of drug discovery and development by Berdigaliyev, Nurken, Aljofan, Mohamad

“…A new medicine will take an average of 10–15 years and more than US$2 billion before it can reach the pharmacy shelf. Traditionally, drug discovery relied on…”
Get full text

The story of EGFR: from signaling pathways to a potent anticancer target by Ramani, Saloni, Samant, Sayalee, Manohar, Sonal M

“…EGFR is a member of the ERBB family. It plays a significant role in cellular processes such as growth, survival and differentiation via the activation of…”
Get full text