Search Results - Massachusetts Medical Society

Covid-19 Vaccine Effectiveness against the Omicron (B.1.1.529) Variant by Andrews, Nick, Stowe, Julia, Kirsebom, Freja, Toffa, Samuel, Rickeard, Tim, Gallagher, Eileen, Gower, Charlotte, Kall, Meaghan, Groves, Natalie, O’Connell, Anne-Marie, Simons, David, Blomquist, Paula B, Zaidi, Asad, Nash, Sophie, Iwani Binti Abdul Aziz, Nurin, Thelwall, Simon, Dabrera, Gavin, Myers, Richard, Amirthalingam, Gayatri, Gharbia, Saheer, Barrett, Jeffrey C, Elson, Richard, Ladhani, Shamez N, Ferguson, Neil, Zambon, Maria, Campbell, Colin N.J, Brown, Kevin, Hopkins, Susan, Chand, Meera, Ramsay, Mary, Lopez Bernal, Jamie

“…In a large case–control study in England, immunity to the omicron variant was very low and less than that to the delta variant 20 weeks after the second…”
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Dexamethasone in Hospitalized Patients with Covid-19 by Horby, Peter, Lim, Wei Shen, Emberson, Jonathan R, Mafham, Marion, Bell, Jennifer L, Linsell, Louise, Staplin, Natalie, Brightling, Christopher, Ustianowski, Andrew, Elmahi, Einas, Prudon, Benjamin, Green, Christopher, Felton, Timothy, Chadwick, David, Rege, Kanchan, Fegan, Christopher, Chappell, Lucy C, Faust, Saul N, Jaki, Thomas, Jeffery, Katie, Montgomery, Alan, Rowan, Kathryn, Juszczak, Edmund, Baillie, J Kenneth, Haynes, Richard, Landray, Martin J

“…Among hospitalized patients with Covid-19, treatment with dexamethasone resulted in lower 28-day mortality than usual care, according to the level of…”
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Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer by Forde, Patrick M., Spicer, Jonathan, Lu, Shun, Provencio, Mariano, Mitsudomi, Tetsuya, Awad, Mark M., Felip, Enriqueta, Broderick, Stephen R., Brahmer, Julie R., Swanson, Scott J., Kerr, Keith, Wang, Changli, Ciuleanu, Tudor-Eliade, Saylors, Gene B., Tanaka, Fumihiro, Ito, Hiroyuki, Chen, Ke-Neng, Liberman, Moishe, Vokes, Everett E., Taube, Janis M., Dorange, Cecile, Cai, Junliang, Fiore, Joseph, Jarkowski, Anthony, Balli, David, Sausen, Mark, Pandya, Dimple, Calvet, Christophe Y., Girard, Nicolas

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Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 by van Doremalen, Neeltje, Bushmaker, Trenton, Morris, Dylan H, Holbrook, Myndi G, Gamble, Amandine, Williamson, Brandi N, Tamin, Azaibi, Harcourt, Jennifer L, Thornburg, Natalie J, Gerber, Susan I, Lloyd-Smith, James O, de Wit, Emmie, Munster, Vincent J

“…In this research letter, investigators report on the stability of SARS-CoV-2 and SARS-CoV-1 under experimental conditions. The viability of the two viruses was…”
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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 by Gordon, Anthony C, Mouncey, Paul R, Al-Beidh, Farah, Rowan, Kathryn M, Nichol, Alistair D, Arabi, Yaseen M, Annane, Djillali, Beane, Abi, van Bentum-Puijk, Wilma, Berry, Lindsay R, Bhimani, Zahra, Bonten, Marc J M, Bradbury, Charlotte A, Brunkhorst, Frank M, Buzgau, Adrian, Cheng, Allen C, Detry, Michelle A, Duffy, Eamon J, Estcourt, Lise J, Fitzgerald, Mark, Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M, Hills, Thomas E, Horvat, Christopher M, Lamontagne, Francois, Lawler, Patrick R, Leavis, Helen L, Linstrum, Kelsey M, Litton, Edward, Lorenzi, Elizabeth, Marshall, John C, Mayr, Florian B, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McVerry, Bryan J, Montgomery, Stephanie K, Morpeth, Susan C, Murthy, Srinivas, Orr, Katrina, Parke, Rachael L, Parker, Jane C, Patanwala, Asad E, Pettilä, Ville, Rademaker, Emma, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Sligl, Wendy I, Turgeon, Alexis F, Turner, Anne M, van de Veerdonk, Frank L, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, McArthur, Colin J, Berry, Scott, Webb, Steve A, Derde, Lennie P G

“…The interleukin-6 receptor blockers tocilizumab and sarilumab were tested against standard care in a randomized trial involving patients newly admitted to the…”
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A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 by Cao, Bin, Wang, Yeming, Wen, Danning, Liu, Wen, Wang, Jingli, Fan, Guohui, Ruan, Lianguo, Song, Bin, Cai, Yanping, Wei, Ming, Li, Xingwang, Xia, Jiaan, Chen, Nanshan, Xiang, Jie, Yu, Ting, Bai, Tao, Xie, Xuelei, Zhang, Li, Li, Caihong, Yuan, Ye, Chen, Hua, Li, Huadong, Huang, Hanping, Tu, Shengjing, Gong, Fengyun, Liu, Ying, Wei, Yuan, Dong, Chongya, Zhou, Fei, Gu, Xiaoying, Xu, Jiuyang, Liu, Zhibo, Zhang, Yi, Li, Hui, Shang, Lianhan, Wang, Ke, Li, Kunxia, Zhou, Xia, Dong, Xuan, Qu, Zhaohui, Lu, Sixia, Hu, Xujuan, Ruan, Shunan, Luo, Shanshan, Wu, Jing, Peng, Lu, Cheng, Fang, Pan, Lihong, Zou, Jun, Jia, Chunmin, Wang, Juan, Liu, Xia, Wang, Shuzhen, Wu, Xudong, Ge, Qin, He, Jing, Zhan, Haiyan, Qiu, Fang, Guo, Li, Huang, Chaolin, Jaki, Thomas, Hayden, Frederick G, Horby, Peter W, Zhang, Dingyu, Wang, Chen

“…Investigators in China report the results of an open-label, randomized clinical trial of lopinavir–ritonavir for the treatment of Covid-19 in 199 infected…”
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Neurologic Features in Severe SARS-CoV-2 Infection by Helms, Julie, Kremer, Stéphane, Merdji, Hamid, Clere-Jehl, Raphaël, Schenck, Malika, Kummerlen, Christine, Collange, Olivier, Boulay, Clotilde, Fafi-Kremer, Samira, Ohana, Mickaël, Anheim, Mathieu, Meziani, Ferhat

“…In a consecutive series of 64 patients with Covid-19 and ARDS, 58 of whom underwent neurologic examination, severe agitation and corticospinal signs were…”
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Multiorgan and Renal Tropism of SARS-CoV-2 by Puelles, Victor G, Lütgehetmann, Marc, Lindenmeyer, Maja T, Sperhake, Jan P, Wong, Milagros N, Allweiss, Lena, Chilla, Silvia, Heinemann, Axel, Wanner, Nicola, Liu, Shuya, Braun, Fabian, Lu, Shun, Pfefferle, Susanne, Schröder, Ann S, Edler, Carolin, Gross, Oliver, Glatzel, Markus, Wichmann, Dominic, Wiech, Thorsten, Kluge, Stefan, Pueschel, Klaus, Aepfelbacher, Martin, Huber, Tobias B

“…In this autopsy series, the authors found that SARS-CoV-2 has an organotropism beyond the respiratory tract, including the kidneys, heart, liver, and brain…”
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Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial by de Koning, Harry J, van der Aalst, Carlijn M, de Jong, Pim A, Scholten, Ernst T, Nackaerts, Kristiaan, Heuvelmans, Marjolein A, Lammers, Jan-Willem J, Weenink, Carla, Yousaf-Khan, Uraujh, Horeweg, Nanda, van ’t Westeinde, Susan, Prokop, Mathias, Mali, Willem P, Mohamed Hoesein, Firdaus A.A, van Ooijen, Peter M.A, Aerts, Joachim G.J.V, den Bakker, Michael A, Thunnissen, Erik, Verschakelen, Johny, Vliegenthart, Rozemarijn, Walter, Joan E, ten Haaf, Kevin, Groen, Harry J.M, Oudkerk, Matthijs

“…High-risk persons were screened for lung cancer in a population-based, randomized, controlled trial that involved volume-based nodule management for further…”
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Head and Neck Cancer by Chow, Laura Q.M

“…Most head and neck cancers (73% in the United States) are now related to human papillomavirus infection rather than tobacco and alcohol. Primary cancers are…”
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Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine by Krammer, Florian, Srivastava, Komal, Alshammary, Hala, Amoako, Angela A, Awawda, Mahmoud H, Beach, Katherine F, Bermúdez-González, Maria C, Bielak, Dominika A, Carreño, Juan M, Chernet, Rachel L, Eaker, Lily Q, Ferreri, Emily D, Floda, Daniel L, Gleason, Charles R, Hamburger, Joshua Z, Jiang, Kaijun, Kleiner, Giulio, Jurczyszak, Denise, Matthews, Julia C, Mendez, Wanni A, Nabeel, Ismail, Mulder, Lubbertus C.F, Raskin, Ariel J, Russo, Kayla T, Salimbangon, Ashley-Beathrese T, Saksena, Miti, Shin, Amber S, Singh, Gagandeep, Sominsky, Levy A, Stadlbauer, Daniel, Wajnberg, Ania, Simon, Viviana

“…Some persons who have recovered from Covid-19 have antibodies to the spike protein of SARS-CoV-2. In 43 such persons who had received a first mRNA vaccine…”
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New-Onset Diabetes in Covid-19 by Rubino, Francesco, Amiel, Stephanie A, Zimmet, Paul, Alberti, George, Bornstein, Stefan, Eckel, Robert H, Mingrone, Geltrude, Boehm, Bernhard, Cooper, Mark E, Chai, Zhonglin, Del Prato, Stefano, Ji, Linong, Hopkins, David, Herman, William H, Khunti, Kamlesh, Mbanya, Jean-Claude, Renard, Eric

“…Diabetes is associated with an increased risk of severe Covid-19. New-onset diabetes and metabolic complications of preexisting diabetes, including diabetic…”
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Immune-Related Adverse Events Associated with Immune Checkpoint Blockade by Postow, Michael A, Sidlow, Robert, Hellmann, Matthew D

“…The wide range of immune-related adverse effects associated with immune checkpoint blockade can complicate this effective therapy and limit its use in patients…”
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Complete Revascularization with Multivessel PCI for Myocardial Infarction by Mehta, Shamir R, Wood, David A, Storey, Robert F, Mehran, Roxana, Bainey, Kevin R, Nguyen, Helen, Meeks, Brandi, Di Pasquale, Giuseppe, López-Sendón, Jose, Faxon, David P, Mauri, Laura, Rao, Sunil V, Feldman, Laurent, Steg, P. Gabriel, Avezum, Álvaro, Sheth, Tej, Pinilla-Echeverri, Natalia, Moreno, Raul, Campo, Gianluca, Wrigley, Benjamin, Kedev, Sasko, Sutton, Andrew, Oliver, Richard, Rodés-Cabau, Josep, Stanković, Goran, Welsh, Robert, Lavi, Shahar, Cantor, Warren J, Wang, Jia, Nakamya, Juliet, Bangdiwala, Shrikant I, Cairns, John A

“…Patients with ST-segment elevation MI and multivessel coronary disease who had undergone successful culprit-lesion PCI were assigned to a strategy of either…”
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Talquetamab, a T-Cell–Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma by Chari, Ajai, Minnema, Monique C., Berdeja, Jesus G., Oriol, Albert, van de Donk, Niels W.C.J., Rodríguez-Otero, Paula, Askari, Elham, Mateos, María-Victoria, Costa, Luciano J., Caers, Jo, Verona, Raluca, Girgis, Suzette, Yang, Shiyi, Goldsmith, Rachel B., Yao, Xiang, Pillarisetti, Kodandaram, Hilder, Brandi W., Russell, Jeffery, Goldberg, Jenna D., Krishnan, Amrita

“…Talquetamab, a bifunctional antibody, directs activated T cells to tumor. In this study, up to 70% of the patients with relapsed or refractory myeloma had a…”
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Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes by Marso, Steven P, Daniels, Gilbert H, Brown-Frandsen, Kirstine, Kristensen, Peter, Mann, Johannes F.E, Nauck, Michael A, Nissen, Steven E, Pocock, Stuart, Poulter, Neil R, Ravn, Lasse S, Steinberg, William M, Stockner, Mette, Zinman, Bernard, Bergenstal, Richard M, Buse, John B

“…Patients with type 2 diabetes and high cardiovascular risk were assigned to receive either the glucagon-like peptide 1 analogue liraglutide or placebo. The…”
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Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors by Strosberg, Jonathan, El-Haddad, Ghassan, Wolin, Edward, Hendifar, Andrew, Yao, James, Chasen, Beth, Mittra, Erik, Kunz, Pamela L, Kulke, Matthew H, Jacene, Heather, Bushnell, David, O’Dorisio, Thomas M, Baum, Richard P, Kulkarni, Harshad R, Caplin, Martyn, Lebtahi, Rachida, Hobday, Timothy, Delpassand, Ebrahim, Van Cutsem, Eric, Benson, Al, Srirajaskanthan, Rajaventhan, Pavel, Marianne, Mora, Jaime, Berlin, Jordan, Grande, Enrique, Reed, Nicholas, Seregni, Ettore, Öberg, Kjell, Lopera Sierra, Maribel, Santoro, Paola, Thevenet, Thomas, Erion, Jack L, Ruszniewski, Philippe, Kwekkeboom, Dik, Krenning, Eric

“…In patients with midgut neuroendocrine tumors that progressed during octreotide analogue therapy, the addition of 177 Lu-Dotatate to octreotide resulted in an…”
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Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes by Wanner, Christoph, Inzucchi, Silvio E, Lachin, John M, Fitchett, David, von Eynatten, Maximilian, Mattheus, Michaela, Johansen, Odd Erik, Woerle, Hans J, Broedl, Uli C, Zinman, Bernard

“…Among patients with type 2 diabetes at high cardiovascular risk, the rates of progression of kidney disease and clinically relevant renal events were lower…”
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Amyotrophic Lateral Sclerosis by Brown, Robert H, Al-Chalabi, Ammar

“…Progress has been made in understanding the genetic defects and the pathophysiology of this crippling motor neuron disease (commonly called Lou Gehrig’s…”
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