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Treatment of metastatic pancreatic adenocarcinoma: a review by Thota, Ramya, Pauff, James M, Berlin, Jordan D

“…Gemcitabine monotherapy has been the standard of care for patients with metastatic pancreatic cancer for several decades. Despite recent advances in various…”
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Heterogeneity and cancer by Allison, Kimberly H, Sledge, George W

“…Cancer heterogeneity, long recognized as an important clinical determinant of patient outcomes, was poorly understood at a molecular level. Genomic studies…”
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An update on gastroenteropancreatic neuroendocrine tumors by Cives, Mauro, Strosberg, Jonathan

“…Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of neoplasms arising from the diffuse neuroendocrine system. The incidence of…”
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The Cancer Genome Atlas: clinical applications for breast cancer by Ma, Cynthia X, Ellis, Matthew J

“…Advances in next-generation sequencing technologies in recent years have allowed in-depth study of somatic mutations in over 1,000 breast cancer samples.The…”
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Chronic inflammation and cancer: the role of the mitochondria by Kamp, David W, Shacter, Emily, Weitzman, Sigmund A

“…Accumulating evidence shows that chronic inflammation can promote all stages of tumorigenesis, including DNA damage, limitless replication, apoptosis evasion,…”
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New biomarkers in prostate cancer by Crawford, E David, Ventii, Karen, Shore, Neal D

“…Prostate cancer (PCa) is the most commonly diagnosed male cancer in the United States. The prostate-specific antigen (PSA) biomarker has been widely used to…”
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The natural history of hormone receptor-positive breast cancer by Lim, Elgene, Metzger-Filho, Otto, Winer, Eric P

“…Approximately 70% of human breast tumors express hormone receptors (HRs), comprising the estrogen receptor (ER) and/or progesterone receptor (PR).The ER is the…”
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Colorectal cancer patients with oligometastatic liver disease: what is the optimal approach? by Weiser, Martin R, Jarnagin, William R, Saltz, Leonard B

“…Although metastatic colorectal cancer is typically incurable, in a good percentage of patients (20% to 50%) who have oligometastatic disease confined to a…”
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Updates on the management of breast cancer brain metastases by Lim, Elgene, Lin, Nancy U

“…Breast cancer brain metastases (BCBMs) are common in patients with advanced disease. Breast cancer subtype and performance status are the major determinants of…”
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Visceral metastases and prostate cancer treatment: 'die hard,' 'tough neighborhoods,' or 'evil humors'? by Drake, Charles G

“…Men with metastatic castration-resistant prostate cancer have multiple treatment options, and the expanding palate of available therapies renders careful…”
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Colorectal cancer: how emerging molecular understanding affects treatment decisions by Sridharan, Meera, Hubbard, Joleen M, Grothey, Axel

“…The medical treatment of metastatic colorectal cancer (mCRC) has advanced significantly over the last 10 years as the result of the introduction of several…”
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Cryoglobulinemic disease by Retamozo, Soledad, Brito-Zerón, Pilar, Bosch, Xavier, Stone, John H, Ramos-Casals, Manuel

“…"Cryoglobulinemia" refers to the presence of cryoglobulins (immunoglobulins that precipitate at variable temperatures < 37 degrees C [98.6 degrees F]) in…”
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The emerging role of HE4 in the evaluation of epithelial ovarian and endometrial carcinomas by Simmons, Archana R, Baggerly, Keith, Bast, Jr, Robert C

“…HE4 (human epididymis protein 4) is overexpressed in both ovarian and endometrial cancers. Levels of the shed HE4 protein are elevated in sera from ovarian and…”
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Pelvic MRI for guiding treatment decisions in rectal cancer by Glynne-Jones, Robert, Tan, David, Goh, Vicky

“…Fluoropyrimidine-based chemoradiation (CRT) is used routinely for locally advanced rectal cancer to shrink the tumor preoperatively, improve lateral surgical…”
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A review of POEMS syndrome by Dispenzieri, Angela, Buadi, Francis K

“…POEMS syndrome is a rare paraneoplastic syndrome that is caused by an underlying plasma cell disorder. Its main features include polyradiculoneuropathy,…”
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Giving honest information to patients with advanced cancer maintains hope by Smith, Thomas J, Dow, Lindsay A, Virago, Enid, Khatcheressian, James, Lyckholm, Laurel J, Matsuyama, Robin

“…Oncologists often do not give honest prognostic and treatment-effect information to patients with advanced disease. One of the primary reasons stated for…”
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My love-hate relationship with hospitals by Hildreth, Craig R

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Survivorship is not a passive sport by Bechhold, Rebecca

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The heavy chain diseases: clinical and pathologic features by Bianchi, Giada, Anderson, Kenneth C, Harris, Nancy Lee, Sohani, Aliyah R

“…Heavy chain diseases are a family of rare, systemic syndromes typically associated with or representing a variant of a B-cell neoplasm. Their characteristic…”
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Cardiovascular toxicity of biologic agents for cancer therapy by Bhave, Manali, Akhter, Nausheen, Rosen, Steven T

“…There has been significant progress in the development of new anticancer therapies over the last decade.Targeted therapies, including anti-human epidermal…”
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