Search Results - Kurth, J.

The Davis-Beirut Reaction: a novel entry into 2H-indazoles and indazolones. Recent biological activity of indazoles by Haddadin, Makhluf J, Conrad, Wayne E, Kurth, Mark J

“…A novel, easy method for the syntheses of richly diversified 2H-indazoles and indazolones, called the Davis-Beirut reaction, and other recent 2H-indazole…”
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Postoperative Apnea in Former Preterm Infants: General Anesthesia or Spinal Anesthesia--Do We Have an Answer? by Kurth, C Dean, Coté, Charles J

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Halothane‐induced hepatitis: Paradigm or paradox for drug‐induced liver injury by Kurth, Mark J, Yokoi, Tsuyoshi, Gershwin, M. Eric

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Synthesis–Spectroscopy Roadmap Problems: Discovering Organic Chemistry by Kurth, Laurie L, Kurth, Mark J

“…Organic chemistry problems that interrelate and integrate synthesis with spectroscopy are presented. These synthesis–spectroscopy roadmap (SSR) problems…”
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Accessing Multiple Classes of 2H‑Indazoles: Mechanistic Implications for the Cadogan and Davis–Beirut Reactions by Zhu, Jie S, Li, Clarabella J, Tsui, Ka Yi, Kraemer, Niklas, Son, Jung-Ho, Haddadin, Makhluf J, Tantillo, Dean J, Kurth, Mark J

“…The Cadogan cyclization is a robust but harsh method for the synthesis of 2H-indazoles, a valuable class of nitrogen heterocycles. Although nitrene generation…”
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Photochemical Preparation of 1,2-Dihydro‑3H‑indazol-3-ones in Aqueous Solvent at Room Temperature by Zhu, Jie S, Kraemer, Niklas, Li, Clarabella J, Haddadin, Makhluf J, Kurth, Mark J

“…o-Nitrosobenzaldehyde is a reactive intermediate useful in the synthesis of nitrogen heterocycles. Previous strategies for using o-nitrosobenzaldehyde involve…”
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Davis–Beirut Reaction: Diverse Chemistries of Highly Reactive Nitroso Intermediates in Heterocycle Synthesis by Zhu, Jie S, Haddadin, Makhluf J, Kurth, Mark J

“…Conspectus Indazoles are an important class of nitrogen heterocycles because of their excellent performance in biologically relevant applications, such as in…”
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N–N Bond Formation between Primary Amines and Nitrosos: Direct Synthesis of 2‑Substituted Indazolones with Mechanistic Insights by Zhu, Jie S, Kraemer, Niklas, Shatskikh, Marina E, Li, Clarabella J, Son, Jung-Ho, Haddadin, Makhluf J, Tantillo, Dean J, Kurth, Mark J

“…A concise, one-step route to indazolones from primary alkyl amines and o-nitrobenzyl alcohols is reported. The key step in this readily scalable indazolone…”
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Davis–Beirut reaction inspired nitroso Diels–Alder reaction by Son, Jung-Ho, Cheung, Amy, Zhu, Jie S., Haddadin, Makhluf J., Kurth, Mark J.

“…[Display omitted] •Davis–Beirut reaction inspired nitroso Diels–Alder protocol.•Nitrophenyl starting material has the para position substituted with a 2°-amine…”
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Self-monitoring of blood glucose in type 2 diabetes and long-term outcome: an epidemiological cohort study by Martin, S, Schneider, B, Heinemann, L, Lodwig, V, Kurth, H.-J, Kolb, H, Scherbaum, W. A

“…Aims/hypothesis The aim of this study was to obtain epidemiological data on self-monitoring of blood glucose (SMBG) in type 2 diabetes and to investigate the…”
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Social discounting of pain by Story, Giles W., Kurth‐Nelson, Zeb, Crockett, Molly, Vlaev, Ivo, Darzi, Ara, Dolan, Raymond J.

“…Impatience can be formalized as a delay discount rate, describing how the subjective value of reward decreases as it is delayed. By analogy, selfishness can be…”
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Dysregulation of intracellular dopamine stores revealed in the R6/2 mouse striatum by Ortiz, Andrea N, Kurth, Benjamin J, Osterhaus, Gregory L, Johnson, Michael A

“…J. Neurochem. (2010) 112, 755-761. Huntington's disease (HD) is a fatal, neurodegenerative movement disorder characterized by preferential and extensive striatal degeneration…”
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Microwave-Assisted Synthesis of 3‑Nitroindoles from N‑Aryl Enamines via Intramolecular Arene–Alkene Coupling by Nguyen, Huy H, Kurth, Mark J

“…A variety of N-aryl β-nitroenamines were effectively transformed into 3-nitroindoles in good yields and with complete regioselectivity via a rapid microwave…”
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Brain Sex in Transgender Women Is Shifted towards Gender Identity by Kurth, Florian, Gaser, Christian, Sánchez, Francisco J, Luders, Eileen

“…Transgender people report discomfort with their birth sex and a strong identification with the opposite sex. The current study was designed to shed further…”
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Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization by Cassidy-Stone, Ann, Chipuk, Jerry E., Ingerman, Elena, Song, Cheng, Yoo, Choong, Kuwana, Tomomi, Kurth, Mark J., Shaw, Jared T., Hinshaw, Jenny E., Green, Douglas R., Nunnari, Jodi

“…Mitochondrial fusion and division play important roles in the regulation of apoptosis. Mitochondrial fusion proteins attenuate apoptosis by inhibiting release…”
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The effect of peri‐operative dexmedetomidine on the incidence of postoperative delirium in cardiac and non‐cardiac surgical patients: a randomised, double‐blind placebo‐controlled trial by van Norden, J., Spies, C. D., Borchers, F., Mertens, M., Kurth, J., Heidgen, J., Pohrt, A., Mueller, A.

“…Summary Delirium occurs commonly following major non‐cardiac and cardiac surgery and is associated with: postoperative mortality; postoperative neurocognitive…”
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The reversal of the rotational modulation rates of the north and south components of Saturn kilometric radiation near equinox by Gurnett, D. A., Groene, J. B., Persoon, A. M., Menietti, J. D., Ye, S.-Y., Kurth, W. S., MacDowall, R. J., Lecacheux, A.

“…It has been known for many years that Saturn emits intense radio emissions at kilometer wavelengths and that this radiation is modulated by the rotation of the…”
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Changes in soil physical and chemical properties following organic matter removal and compaction: 20-year response of the aspen Lake-States Long Term Soil Productivity installations by Slesak, Robert A., Palik, Brian J., D'Amato, Anthony W., Kurth, Valerie J.

“…•Organic matter (OM) removal and compaction assessed across soil texture gradient.•OM effect primarily associated with extreme forest floor removal at low…”
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Carbon−Carbon Bond-Forming Solid-Phase Reactions. Part II by Sammelson, Robert E, Kurth, Mark J

“…Solid-phase organic synthesis has become a very efficient model for production of combinatorial libraries, and with the implementation of high-throughput…”
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Davis–Beirut Reaction: Route to Thiazolo‑, Thiazino‑, and Thiazepino‑2H‑indazoles by Farber, Kelli M, Haddadin, Makhluf J, Kurth, Mark J

“…Methods for the construction of thiazolo-, thiazino-, and thiazepino-2H-indazoles from o-nitrobenzaldehydes or o-nitrobenzyl bromides and S-trityl-protected…”
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