Search Results - Gionata Fiorino

Anti-TNF Biosimilars in Inflammatory Bowel Disease: Searching the Proper Patient's Profile by Danese, Silvio, Fiorino, Gionata

“…Biosimilars of infliximab (CT-P13) are currently approved and available for the same indications as for the originator. Some concerns about safety and…”
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Calcium supplementation for the prevention of colorectal adenomas: a systematic review and meta-analysis of randomized controlled trials by Bonovas, Stefanos, Fiorino, Gionata, Lytras, Theodore, Malesci, Alberto, Danese, Silvio

“…AIM: To determine the efficacy of calcium supplementation in reducing the recurrence of colorectal adenomas.METHODS: We conducted a systematic review and…”
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Psoriasis and Inflammatory Bowel Disease: Two Sides of the Same Coin? by Fiorino, Gionata, Omodei, Paolo D.

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The biosimilar road in inflammatory bowel disease: The right way? by Fiorino, Gionata, MD, PhD, Danese, Silvio, MD, PhD

“…Abstract The biologicals have led to dramatic changes in the management of immune-mediated diseases, and the subsequent development of their biosimilars may…”
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Adalimumab and Azathioprine Combination Therapy for Crohn’s Disease: A Shining Diamond? by Fiorino, Gionata, Danese, Silvio

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The clinical potential of etrolizumab in ulcerative colitis: hypes and hopes by Fiorino, Gionata, Gilardi, Daniela, Danese, Silvio

“…Antiadhesion molecules are effective and safe in patients with ulcerative colitis (UC). Etrolizumab, a monoclonal antibody targeting both α4β7 and αEβ7,…”
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Novel therapeutic targets for inflammatory bowel disease by Argollo, Marjorie, Fiorino, Gionata, Hindryckx, Pieter, Peyrin-Biroulet, Laurent, Danese, Silvio

“…Inflammatory bowel disease (IBD), including Crohn's disease (CD) and Ulcerative Colitis (UC), are immune mediated conditions associated with progressive damage…”
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Biological Agents for Moderately to Severely Active Ulcerative Colitis by DANESE, Silvio, FIORINO, Gionata, PEYRIN-BIROULET, Laurent, LUCENTEFORTE, Ersilia, VIRGILI, Gianni, MOJA, Lorenzo, BONOVAS, Stefanos

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A Surface Plasmon Resonance-based assay to measure serum concentrations of therapeutic antibodies and anti-drug antibodies by Beeg, Marten, Nobili, Alessandro, Orsini, Barbara, Rogai, Francesca, Gilardi, Daniela, Fiorino, Gionata, Danese, Silvio, Salmona, Mario, Garattini, Silvio, Gobbi, Marco

“…Therapeutic drug and immunogenicity monitoring (TDIM) is increasingly proposed to guide therapy with biologics, characterised by high inter-individual…”
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Tofacitinib in the treatment of ulcerative colitis: efficacy and safety from clinical trials to real-world experience by D’Amico, Ferdinando, Parigi, Tommaso Lorenzo, Fiorino, Gionata, Peyrin-Biroulet, Laurent, Danese, Silvio

“…Tofacitinib is an oral small molecule directed against the JAK/STAT pathway, blocking the inflammatory cascade. Oral formulation of tofacitinib has recently…”
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The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges by Noviello, Daniele, Mager, Riccardo, Roda, Giulia, Borroni, Riccardo G., Fiorino, Gionata, Vetrano, Stefania

“…Ulcerative colitis (UC) is a chronic relapsing disorder of the colonic tract, characterized by a dysregulated innate and adaptive immune response to gut…”
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ECCO Position Statement on the Use of Biosimilars for Inflammatory Bowel Disease-An Update by Danese, Silvio, Fiorino, Gionata, Raine, Tim, Ferrante, Marc, Kemp, Karen, Kierkus, Jaroslaw, Lakatos, Peter L, Mantzaris, Gerassimos, van der Woude, Janneke, Panes, Julian, Peyrin-Biroulet, Laurent

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Accuracy of Humanitas Ultrasound Criteria in Assessing Disease Activity and Severity in Ulcerative Colitis: A Prospective Study by Allocca, Mariangela, Fiorino, Gionata, Bonovas, Stefanos, Furfaro, Federica, Gilardi, Daniela, Argollo, Marjorie, Magnoni, Paola, Peyrin-Biroulet, Laurent, Danese, Silvio

“…Colonoscopy [CS] is the standard for assessing disease activity in ulcerative colitis [UC], although invasive and poorly tolerated. Bowel ultrasound [BUS] may…”
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Absence of COVID-19 Infection in Patients Accessing IBD Unit at Humanitas, Milan: Implications for Postlockdown Measures by Fiorino, Gionata, Gilardi, Daniela, Radice, Simona, Furfaro, Federica, Allocca, Mariangela, Danese, Silvio

“…The risk of coronavirus disease-19 infection for healthcare professionals and patients in hospitals remains unclear. We investigated whether precautions…”
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Anti-IL-6 treatment for inflammatory bowel diseases: next cytokine, next target by Allocca, Mariangela, Jovani, Manol, Fiorino, Gionata, Schreiber, Stefan, Danese, Silvio

“…Inflammatory bowel diseases (IBD) are chronic, relapsing, and destructive inflammatory disorders of the gastrointestinal tract. Both Crohn's disease (CD) and…”
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The Experience with Biosimilars of Infliximab in Inflammatory Bowel Disease by Avila-Ribeiro, Pedro, Fiorino, Gionata, Danese, Silvio

“…biosimilars are similar versions of existing innovator biologic agents but with distinct manufacturing processes. They were approved in inflammatory bowel…”
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The gut-brain axis: Correlation of choroid plexus volume and permeability with inflammatory biomarkers in Crohn's disease by Bonifacio, Cristiana, Savini, Giovanni, Reca, Christian, Garoli, Federico, Levi, Riccardo, Vatteroni, Giulia, Balzarini, Luca, Allocca, Mariangela, Furfaro, Federica, Dal Buono, Arianna, Armuzzi, Alessandro, Danese, Silvio, Matteoli, Michela, Rescigno, Maria, Fiorino, Gionata, Politi, Letterio S.

“…The dysregulation of the gut-brain axis in chronic inflammatory bowel diseases can cause neuro-psychological disturbances, but the underlying mechanisms are…”
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Consensus report: clinical recommendations for the prevention and management of the nocebo effect in biosimilar‐treated IBD patients by Pouillon, Lieven, Danese, Silvio, Hart, Ailsa, Fiorino, Gionata, Argollo, Marjorie, Selmi, Carlo, Carlo‐Stella, Carmelo, Loeuille, Damien, Costanzo, Antonio, Lopez, Anthony, Vegni, Elena, Radice, Simona, Gilardi, Daniela, Socha, Marie, Fazio, Maria, González‐Lorenzo, Marien, Bonovas, Stefanos, Magro, Fernando, Peyrin‐Biroulet, Laurent

“…Summary Background The nocebo effect is a negative effect of a pharmacological or nonpharmacological medical treatment that is induced by patients'…”
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Proactive TDM for Crohn’s Disease Patients in Clinical Remission Under Anti-TNF Treatment: Current State of Evidence by Torres, Joana, Bonovas, Stefanos, Fiorino, Gionata

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First-line therapy in adult Crohn's disease: who should receive anti-TNF agents? by Peyrin-Biroulet, Laurent, Fiorino, Gionata, Buisson, Anthony, Danese, Silvio

“…Therapy for Crohn's disease has traditionally been based on a step-up approach, with treatment with the powerful TNF antagonists reserved as a last resort…”
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