Search Results - Emiliano C. C. Pozzi

Therapeutic efficacy of boron neutron capture therapy mediated by boron-rich liposomes for oral cancer in the hamster cheek pouch model by Heber, Elisa M., Hawthorne, M. Frederick, Kueffer, Peter J., Garabalino, Marcela A., Thorp, Silvia I., Pozzi, Emiliano C. C., Hughes, Andrea Monti, Maitz, Charles A., Jalisatgi, Satish S., Nigg, David W., Curotto, Paula, Trivillin, Verónica A., Schwint, Amanda E.

“…The application of boron neutron capture therapy (BNCT) mediated by liposomes containing ¹⁰B-enriched polyhedral borane and carborane derivatives for the…”
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Optimization of the classical oral cancerization protocol in hamster to study oral cancer therapy by Santa Cruz, Iara S., Garabalino, Marcela A., Trivillin, Verónica A., Itoiz, María E., Pozzi, Emiliano C. C., Thorp, Silvia, Curotto, Paula, Guidobono, Juan S., Heber, Elisa M., Nigg, David W., Schwint, Amanda E., Monti Hughes, Andrea

“…Objective(s) The hamster carcinogenesis model recapitulates oral oncogenesis. Dimethylbenz[a]anthracene (DMBA) cancerization induces early severe mucositis,…”
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Abscopal effect of boron neutron capture therapy (BNCT): proof of principle in an experimental model of colon cancer by Trivillin, Verónica A., Pozzi, Emiliano C. C., Colombo, Lucas L., Thorp, Silvia I., Garabalino, Marcela A., Monti Hughes, Andrea, González, Sara J., Farías, Rubén O., Curotto, Paula, Santa Cruz, Gustavo A., Carando, Daniel G., Schwint, Amanda E.

“…The aim of the present study was to evaluate, for the first time, the abscopal effect of boron neutron capture therapy (BNCT). Twenty-six BDIX rats were…”
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“Sequential” Boron Neutron Capture Therapy (BNCT): A Novel Approach to BNCT for the Treatment of Oral Cancer in the Hamster Cheek Pouch Model by Molinari, Ana J, Pozzi, Emiliano C. C, Hughes, Andrea Monti, Heber, Elisa M, Garabalino, Marcela A, Thorp, Silvia I, Miller, Marcelo, Itoiz, Maria E, Aromando, Romina F, Nigg, David W, Quintana, Jorge, Santa Cruz, Gustavo A, Trivillin, Verónica A, Schwint, Amanda E

“…In the present study the therapeutic effect and potential toxicity of the novel “Sequential” boron neutron capture therapy (Seq-BNCT) for the treatment of oral…”
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Tumor Blood Vessel “Normalization” Improves the Therapeutic Efficacy of Boron Neutron Capture Therapy (BNCT) in Experimental Oral Cancer by Molinari, Ana J., Pozzi, Emiliano C. C., Hughes, Andrea Monti, Heber, Elisa M., Garabalino, Marcela A., Thorp, Silvia I., Miller, Marcelo, Itoiz, Maria E., Aromando, Romina F., Nigg, David W., Trivillin, Verónica A., Schwint, Amanda E.

“…We previously demonstrated the efficacy of BNCT mediated by boronophenylalanine (BPA) to treat tumors in a hamster cheek pouch model of oral cancer with no…”
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Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model by Garabalino, Marcela A., Olaiz, Nahuel, Portu, Agustina, Saint Martin, Gisela, Thorp, Silvia I., Pozzi, Emiliano C. C., Curotto, Paula, Itoiz, María E., Monti Hughes, Andrea, Colombo, Lucas L., Nigg, David W., Trivillin, Verónica A., Marshall, Guillermo, Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) is a promising cancer binary therapy modality that utilizes the nuclear capture reaction of thermal neutrons by boron-10…”
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Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new “B2” configuration of the RA-6 nuclear reactor by Monti Hughes, Andrea, Longhino, Juan, Boggio, Esteban, Medina, Vanina A., Martinel Lamas, Diego J., Garabalino, Marcela A., Heber, Elisa M., Pozzi, Emiliano C. C., Itoiz, María E., Aromando, Romina F., Nigg, David W., Trivillin, Verónica A., Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) is based on selective accumulation of B-10 carriers in tumor followed by neutron irradiation. We demonstrated, in 2001,…”
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Boron neutron capture therapy (BNCT) for liver metastasis: therapeutic efficacy in an experimental model by Pozzi, Emiliano C. C., Cardoso, Jorge E., Colombo, Lucas L., Thorp, Silvia, Monti Hughes, Andrea, Molinari, Ana J., Garabalino, Marcela A., Heber, Elisa M., Miller, Marcelo, Itoiz, Maria E., Aromando, Romina F., Nigg, David W., Quintana, Jorge, Trivillin, Verónica A., Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) was proposed for untreatable colorectal liver metastases. The present study evaluates tumor control and potential…”
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Boron neutron capture therapy (BNCT) for the treatment of liver metastases: biodistribution studies of boron compounds in an experimental model by Garabalino, Marcela A, Monti Hughes, Andrea, Molinari, Ana J, Heber, Elisa M, Pozzi, Emiliano C. C, Cardoso, Jorge E, Colombo, Lucas L, Nievas, Susana, Nigg, David W, Aromando, Romina F, Itoiz, Maria E, Trivillin, Verónica A, Schwint, Amanda E

“…We previously demonstrated the therapeutic efficacy of different boron neutron capture therapy (BNCT) protocols in an experimental model of oral cancer. BNCT…”
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Blood Vessel Normalization in the Hamster Oral Cancer Model for Experimental Cancer Therapy Studies by MOLINARI, Ana J, AROMANDO, Romina F, ITOIZ, Maria E, GARABALINO, Marcela A, MONTI HUGHES, Andrea, HEBER, Elisa M, POZZI, Emiliano C. C, NIGG, David W, TRIVILLIN, Veronica A, SCHWINT, Amanda E

“…Normalization of tumor blood vessels improves drug and oxygen delivery to cancer cells. The aim of this study was to develop a technique to normalize blood…”
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Assessing advantages of sequential boron neutron capture therapy (BNCT) in an oral cancer model with normalized blood vessels by Molinari, Ana J, Thorp, Silvia I, Portu, Agustina M, Saint Martin, Gisela, Pozzi, Emiliano C C, Heber, Elisa M, Bortolussi, Silva, Itoiz, Maria E, Aromando, Romina F, Monti Hughes, Andrea, Garabalino, Marcela A, Altieri, Saverio, Trivillin, Verónica A, Schwint, Amanda E

“…We previously demonstrated the therapeutic success of sequential boron neutron capture therapy (Seq-BNCT) in the hamster cheek pouch oral cancer model. It…”
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Boron Neutron Capture Therapy (BNCT) in an oral precancer model: Therapeutic benefits and potential toxicity of a double application of BNCT with a six-week interval by Monti Hughes, Andrea, Pozzi, Emiliano C.C, Heber, Elisa M, Thorp, Silvia, Miller, Marcelo, Itoiz, Maria E, Aromando, Romina F, Molinari, Ana J, Garabalino, Marcela A, Nigg, David W, Trivillin, Verónica A, Schwint, Amanda E

“…Summary Given the clinical relevance of locoregional recurrences in head and neck cancer, we developed a novel experimental model of premalignant tissue in the…”
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Boron neutron capture therapy (BNCT) for liver metastasis in an experimental model: dose–response at five-week follow-up based on retrospective dose assessment in individual rats by Pozzi, Emiliano C. C., Trivillin, Verónica A., Colombo, Lucas L., Monti Hughes, Andrea, Thorp, Silvia I., Cardoso, Jorge E., Garabalino, Marcela A., Molinari, Ana J., Heber, Elisa M., Curotto, Paula, Miller, Marcelo, Itoiz, Maria E., Aromando, Romina F., Nigg, David W., Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) was proposed for untreatable colorectal liver metastases. Employing an experimental model of liver metastases in rats, we…”
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Boron delivery with liposomes for boron neutron capture therapy (BNCT): biodistribution studies in an experimental model of oral cancer demonstrating therapeutic potential by Heber, Elisa M., Kueffer, Peter J., Lee, Mark W., Hawthorne, M. Frederick, Garabalino, Marcela A., Molinari, Ana J., Nigg, David W., Bauer, William, Hughes, Andrea Monti, Pozzi, Emiliano C. C., Trivillin, Verónica A., Schwint, Amanda E.

“… different liposome formulations that were previously tested for a different pathology, i.e., in experimental mammary carcinoma in BALB/c mice…”
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Biodistribution of sodium borocaptate (BSH) for boron neutron capture therapy (BNCT) in an oral cancer model by Garabalino, Marcela A., Heber, Elisa M., Hughes, Andrea Monti, González, Sara J., Molinari, Ana J., Pozzi, Emiliano C. C., Nievas, Susana, Itoiz, Maria E., Aromando, Romina F., Nigg, David W., Bauer, William, Trivillin, Verónica A., Schwint, Amanda E.

“…Boron neutron capture therapy (BNCT) is based on selective accumulation of 10 B carriers in tumor followed by neutron irradiation. We previously proved the…”
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Cobaltabis(Dicarbollide) [ o -COSAN] - for Boron Neutron Capture Therapy of Head and Neck Cancer: Biodistribution and Irradiation Studies in an Experimental Oral Cancer Model by Palmieri, Mónica A, Monti Hughes, Andrea, Trivillin, Verónica A, Garabalino, Marcela A, Ramos, Paula S, Thorp, Silvia I, Curotto, Paula, Pozzi, Emiliano C C, Nuez Martínez, Miquel, Teixidor, Francesc, Viñas, Clara, Schwint, Amanda E

“… Based on previous studies in tumor-bearing mice, this study evaluated the biodistribution of the sodium salt of cobaltabis(dicarbollide) (Na[3,3'-Co(C B H ) ], abbreviated as Na[ -COSAN…”
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Enhancement in the Therapeutic Efficacy of In Vivo BNCT Mediated by GB-10 with Electroporation in a Model of Oral Cancer by Olaiz, Nahuel, Monti Hughes, Andrea, Pozzi, Emiliano C C, Thorp, Silvia, Curotto, Paula, Trivillin, Verónica A, Ramos, Paula S, Palmieri, Mónica A, Marshall, Guillermo, Schwint, Amanda E, Garabalino, Marcela A

“…Boron neutron capture therapy (BNCT) combines preferential tumor uptake of B compounds and neutron irradiation. Electroporation induces an increase in the…”
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Therapeutic Efficacy, Radiotoxicity and Abscopal Effect of BNCT at the RA-3 Nuclear Reactor Employing Oligo-Fucoidan and Glutamine as Adjuvants in an Ectopic Colon Cancer Model in Rats by Frydryk Benitez, Debora N, Palmieri, Mónica A, Langle, Yanina V, Monti Hughes, Andrea, Pozzi, Emiliano C C, Thorp, Silvia I, Garabalino, Marcela A, Curotto, Paula, Ramos, Paula S, Paparella, María L, Polti, Lucas, Eiján, Ana, Schwint, Amanda E, Trivillin, Verónica A

“…Boron neutron capture therapy (BNCT) is based on the preferential uptake of B compounds by tumors, followed by neutron irradiation. The aim of this study was…”
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Boron neutron capture synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: radiobiological studies at RA-1 Nuclear Reactor in a model of antigen-induced arthritis in rabbits by Trivillin, Verónica A., Bruno, Leandro J., Gatti, David A., Stur, Mariela, Garabalino, Marcela A., Hughes, Andrea Monti, Castillo, Jorge, Pozzi, Emiliano C. C., Wentzeis, Luis, Scolari, Hugo, Schwint, Amanda E., Feldman, Sara

“…Rheumatoid arthritis is a chronic autoimmune pathology characterized by the proliferation and inflammation of the synovium. Boron neutron capture synovectomy…”
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Boron Neutron Capture Therapy (BNCT) Mediated by Maleimide-Functionalized Closo-Dodecaborate Albumin Conjugates (MID:BSA) for Oral Cancer: Biodistribution Studies and In Vivo BNCT in the Hamster Cheek Pouch Oral Cancer Model by Monti Hughes, Andrea, Goldfinger, Jessica A., Palmieri, Mónica A., Ramos, Paula, Santa Cruz, Iara S., De Leo, Luciana, Garabalino, Marcela A., Thorp, Silvia I., Curotto, Paula, Pozzi, Emiliano C. C., Kawai, Kazuki, Sato, Shinichi, Itoiz, María E., Trivillin, Verónica A., Guidobono, Juan S., Nakamura, Hiroyuki, Schwint, Amanda E.

“…Background: BNCT (Boron Neutron Capture Therapy) is a tumor-selective particle radiotherapy that combines preferential boron accumulation in tumors and neutron…”
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