Search Results - Egyptian Society of Human Genetics

Association of insulin gene VNTR INS -23/Hphl A>T (rs689) polymorphism with type 1 diabetes mellitus in Egyptian children by Qasim, Samar H., Ubayd, Jamal T. A., Ibrahim, Amani, Bazaraa, Hafiz, Kamal, Azzah M., Mira, Marwah F., Amin, Maha, Salah, Narmin, Radwan, Iman R., Mamduh, Muna, Badawi, Nura

“…Background: Typel diabetes mellitus (T1DM) has a multi-factorial pathogenesis; the interplay between genetic susceptibility and environmental factors is…”
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Serum level and single-nucleotide polymorphisms of toll-like receptor-7 among urinary bladder cancer Iraqi patients by al-Humairi, Rasha M. A., Adhiah, Ali K., al-Musawi, Muna T.

“…Background: Toll-like receptor 7 (TLR7), a member of TLR family, plays a pivotal role in pathogenesis of different malignancies. Among these is urinary bladder…”
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Prognostic implications of IDH1 rs11554137 and IDH2R140Q SNPs mutations in cytogenetically normal acute myeloid leukemia by Abd al-Maqsud, Sahar Samir, Ajami, Hibah Sami, al-Jamal, Rasha Abd al-Rahman, Pissar, Shayma Abd al-Malak, Salim, Daliyah Diya al-Din, Abd al-Sami, Hana Fathi

“…Background: Mutant isocitrate dehydrogenase (IDH) 1 and 2 alter the epigenetic landscape in acute myeloid leukemia (AML) cells through production of the…”
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Telomere reprogramming during fetal life in low socioeconomic mothers by Farrukh, Sadia, Baij, Saidah, Husayn, Rubina F., Shahid, Aqsa, Khan, Samahir Tariq

“…Background: Relative telomere length (RTL), the biological chronometer, varies considerably among individuals under the influence of multiple risk factors such…”
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Association study of APOE gene polymorphisms with diabetes and the main ardiometabolic risk factors, in the Algerian population by Majawi, Iman Hammani, Huti, Layla, Bu Linawar, Husam, Bin Shakur, Suniya Madyani, Jalluli, Hajir Wuhaybi, Hatraf, Sarah Aishah Larjam

“…Background: Metabolic syndrome (MetS) represents a combination of at least three primary metabolic abnormalities among which obesity, hyperglycemia,…”
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Genotyping of PPAR-c gene polymorphism in Egyptian neonates affected with sepsis disease and its severity by Shawqi, Rabah M., al-Nadi, Ghadah H., Rafat, Shayma Muhammad, Kamal, Tariq M.

“…Background : Peroxisome Proliferator-Activated Receptor gamma (PPARc) is a ligand-dependent transcription factor involved in inflammatory process. PPAR-c gene…”
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Helicobacter pylori western cagA genotype in Egyptian patients withupper gastrointestinal disease by Sabir, Muhammad, Diyab, Manal, al-Sharbini, Afat, Shimis, Muhammad, Jamal, Dua, al-Shinnawi, Ahmad, al-Ghannam, Majid T.

“…Background: Infection with Helicobacter pylori (H. pylori) causes persistent gastritis that may progress to fatal gastric cancer. The cytotoxin-associated gene…”
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Computer-aided identification of lung cancer inhibitors through homology modeling and virtual screening by Haredi Abdelmonsef, Aboubakr

“…Background: Lung cancer is the most often event cancer around the world and the first leading cause of cancer death in human beings. Rab39a protein is…”
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Cytogenetical analysis in blood lymphocytes of cigarette smokers in Tiruchirappalli district, Tamil Nadu, India by Balachandar, Vellingiri, Karthickkumar, Alagamuthu, Bukhari, A. Sadiq, Muhammad, H. E. Sayyid, Periyasamy, M., Christobher, S.

“…Background: Tobacco smoke causes serious health ill effects to human population. Cancer and cardiovascular diseases are more common in smoking subjects. Aim:…”
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Extremely low frequency electromagnetic field in combination with B-lapachone up-regulates the genes of non-homologous end joining by Sanie Jahromi, Fatimah, Sadat, Mustafa, Mahmoudinasab, Hamidah

“…Background and purpose : Non-homologous end joining (NHEJ) is the major pathway for removing DNA double strand breaks lesions. NHEJ is considered to be a…”
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Can food addiction replace binge eating assessment in obesity clinics ? by Abd al-Aziz, Iman Amin, al-Shahhat, Asma Abd al-Fattah, Sayyid, Amani Muhammad, Ahmad, Ala Yusuf

“…Introduction: Food addiction (FA) is a new terminology that uses the similarities between the craving for food and drug addiction. The Yale Food Addiction…”
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Distribution of HLA-DRB1/ DQB1alleles and DRB1-DQB1haplotypes among Tunisian patients with autoimmune hepatitis by Chaouali, Marwa, Kochkar, Radyah, Messadi, Amirah, Tezeghdenti, Ayman, Ibn Aziz, Muna, Ibn Abd Allah, Hatim, Yaqubi-Oueslati, Basmah, Ghazwani, Izz al-Din

“…Background : Autoimmune hepatitis (AIH) is a chronic inflammatory disease characterized by necrotic inflammation leading to hepatocyte destruction. The…”
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Micro RNA-146a expression as a potential biomarker for rheumatoid arthritis in Egypt by Murshidi, Nashwh Ali, Ibrahim, Ayman Asaad, Khatir, Wala Shawqi, Hamdi, Maha Salah Al-Din, al-Sayyid, Hibah Muhammad Abd al-Qadir

“…MicroRNAs (miRNAs) are small non-coding RNAs, whose role in regulating diverse immune functions, suggests they might play a role as biomarkers for immune…”
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The B fibrinogen gene G-455A polymorphism in Asian subjects with coronary heart disease : a meta analysis by Fajar, Jonny Karunia

“…Background : There are many studies about the association of b fibrinogen gene G-455A polymorphism and the risk of coronary heart disease (CHD). However, the…”
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PAX5a and PAX5b mRNA expression in breast cancer : relation to serum P53 and MMP2 by Ahmad, Manal Basyuni, Nabih, Inas Samir, al-Shihah, Munirah

“…Background: Many studies evaluated the role of paired box gene 5 (PAX5) in breast cancer. However, few investigated PAX5a and PAX5b isoforms individually…”
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PPAR-c and CYP 46 A1 genes polymorphism is associated with primary open angle glaucoma (poag) in hypertensive north Indians by Mahdi, Farzana, Zaidi, Ziashan Haydar, Abbas, Shania, Singh, Luxmi, Rizvi, Salihah, Raza, Sayyid Tasleem

“…Background: Involvement of genetic factors like gene polymorphisms was found to contribute significantly to development and progression of Primary Open Angle…”
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A germ line RET proto-oncogene mutation in multiple members of an Arab family with variable onset of MEN type 2 A-associated clinical manifestations by Dashti, Muhammad, al-Shatti, Abd al-Rahman, Marafi, Makia J., Sulayman, Ibrahim, Rida, Abd Allah M.

“…Multiple endocrine neoplasia type 2A (MEN2A) is a rare cancer associated-syndrome, inherited in an autosomal dominant fashion and caused by germline mutation…”
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Identification of mutations in Iranian patients’ DAX-1 gene with x-linked adrenal hypoplasia congenital by Hamzihloie, Tibah, Vakili, Rahim, Eshraghi, Peyman, Davoodnejad, Mahdiyah

“…Objective(s): X-linked adrenal hypoplasia congenital (X-linked AHC) is a rare disorder, characterized by infantile-onset acute primary adrenal insufficiency…”
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The association of single nucleotide polymorphism of interleukin-21 gene and serum interleukin-21 levels with systemic lupus erythematosus by Murshidi, Nashwh Ali, Hafiz, Shirin Fawzi, Irfan, Dina M., Ahmad, Yasamin Muhammad, Shihatah, Iman Husayn

“…Background: Systemic lupus erythematosus (SLE) is a common autoimmune disorder which commonly results from the combined effects of a large number of genes…”
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Molecular genetic analysis of type II diabetes associated m. 3243A >G mitochondrial DNA mutation in a Pakistani family by Nouroz, Faysal, Bibi, Nousheen, Khan, Sulayman, Muhammad, Khushi, Abrar, Saidul, Zaman, Hasanayn

“…Background: Type II diabetes is the most often considered as maternally inherited disease and A>G transition at position 3243 of mitochondrial DNA (m.3243A>G)…”
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