Search Results - Ecca, Fabrizio
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Rare genetic variant burden in DPYD predicts severe fluoropyrimidine-related toxicity risk
Published in Biomedicine & pharmacotherapy (01-10-2022)“…Preemptive targeted pharmacogenetic testing of candidate variations in DPYD is currently being used to limit toxicity associated with fluoropyrimidines. The…”
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Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC)
Published in Cells (Basel, Switzerland) (01-10-2019)“…Carboplatin/paclitaxel is the reference regimen in the treatment of advanced high-grade serous ovarian cancer (HGSOC) in neo-adjuvant chemotherapy (NACT)…”
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Estimating the Effectiveness of DPYD Genotyping in Italian Individuals Suffering from Cancer Based on the Cost of Chemotherapy-Induced Toxicity
Published in American journal of human genetics (06-06-2019)“…Fluoropyrimidines (FLs) have been widely used for more than 60 years against a range of solid tumors and still remains the cornerstone for the treatment of…”
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Host genetic profiling to increase drug safety in colorectal cancer from discovery to implementation
Published in Drug resistance updates (01-07-2018)“…Adverse events affect the pharmacological treatment of approximately 90% of colorectal cancer (CRC) patients at any stage of the disease. Chemotherapy…”
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Immunogenetics of prostate cancer: a still unexplored field of study
Published in Pharmacogenomics (01-02-2018)“…The immune system is a double-edged sword with regard to the prostate cancer (PCa) battle. Immunogenetics, the study of the potential role of immune-related…”
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Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects
Published in Journal of cellular physiology (01-09-2019)“…Peptidyl‐prolyl cis–trans isomerase, NIMA‐interacting 1 (PIN1) is a peptidyl‐prolyl isomerase that binds phospho‐Ser/Thr‐Pro motifs in proteins and catalyzes…”
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The Genotype for DPYD Risk Variants in Patients With Colorectal Cancer and the Related Toxicity Management Costs in Clinical Practice
Published in Clinical pharmacology and therapeutics (01-04-2019)“…Lack of information on the clinical utility of preemptive DPYD screening before fluoropyrimidine treatment is a major barrier preventing its use in clinical…”
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The use of pharmacogenetics to increase the safety of colorectal cancer patients treated with fluoropyrimidines
Published in Cancer drug resistance (01-01-2019)“…Fluoropyrimidines (FP) are given in the combination treatment of the advanced disease or as monotherapy in the neo-adjuvant and adjuvant treatment of…”
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What drives the substitutability between native and foreign workers? Evidence about the role of language
Published in Economica (London) (01-01-2024)“…This paper investigates the role of language in determining the substitutability between foreign and native workers. Our identification strategy exploits the…”
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Non‐standard Employment and Rent‐sharing
Published in Economica (London) (01-01-2023)“…In this paper, we analyse how non‐standard (or non‐regular) employment affects the capacity of regular workers to appropriate rents. In this context, we first…”
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Contratto ed emergenza sanitaria in Italia
Published in Revista de Direito da Cidade (23-09-2021)“… di mutuo, contratti bancari e assicurativi, ecc. Verificherà fino a che punto la situazione sociale, sanitaria, economica e istituzionale determinata dalla pandemia…”
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CONTRACT AND HEALTH EMERGENCY IN ITALY/CONTRATTO ED EMERGENZA SANITARIA IN ITALIA/CONTRATO E EMERGENCIA SANITARIA NA ITALIA
Published in Revista de Direito da Cidade (01-09-2021)“…This paper aims to analyze the global disaster caused by the COVID-19 pandemic that has disrupted the existence of almost all of humanity. In addition, examine…”
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Retrofitting dello spazio pubblico per la qualità ambientale ed ecosistemica di città più "Green"
Published in Techne (Florence, Italy : 2011) (01-01-2020)“… (distretti urbani, quartieri, aggregati edilizi, ecc.) nelle quali diventa elemento-chiave l'incremento della qualitâ…”
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La tradizione manoscritta delle canzoni di Bernart de Ventadorn: appunti di critica esterna
Published in Carte romanze (01-07-2014)“… Le analisi, anche con prospettive di ricerca differenti e ulteriori (stratigrafia e genesi dei raggruppamenti, quadro delle attribuzioni, ecc…”
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Lo Stato come 'fornitore' d'investimenti sociali (State as Social Investments Provider)
Published in Moneta e Credito (01-04-2016)“…We analyze the role of the State in social investment (education, health services, etc.), different from those in infrastructures. We do so because, in the…”
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Un futuro chiamato Constellation
Published in GEOmedia (01-03-2007)“… non può essere sviluppato e realizzato in pochi mesi, ecco che l’annuncio a carattere politico del Presidente è realmente diventato un piano operativo che vedrà i suoi primi frutti nel volo abitato entro cinque o sei anni…”
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18
Un futuro chiamato Constellation
Published in GEOmedia (01-03-2007)“… non può essere sviluppato e realizzato in pochi mesi, ecco che l’annuncio a carattere politico del Presidente è realmente diventato un piano operativo che vedrà i suoi primi frutti nel volo abitato entro cinque o sei anni…”
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φηγῶι ὑπὸ πρέμνωι (Call. h. 3, 239)
Published in Materiali e discussioni per l'analisi dei testi classici (01-01-2017)“… tràdito è sano e che l'espressione è modellata sui nessi omerici νηί παρά πρύμνηι (H 383 ecc.) and νηί δ' ένί πρύμνηι (K 570 ecc.)…”
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PAVESE CLASSICO NOSTRO CONTEMPORANEO (CINQUANT' ANNI DOPO)
Published in Italianistica (01-09-2015)“… logoro del cerimoniale, quanto per stimolare il risveglio di buoni studi. Ecco che, a cinquantanni esatti dalla pubblicazione del celebre numero della rivista «Sigma…”
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