Search Results - Catalano, Carlos Enrique

Strong subunit coordination drives a powerful viral DNA packaging motor by Andrews, Benjamin T., Catalano, Carlos Enrique

“…Terminase enzymes are viral motors that package DNA into a preformed capsid and are of interest both therapeutically and as potential nano-machines. The…”
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Major capsid reinforcement by a minor protein in herpesviruses and phage by Sae-Ueng, Udom, Liu, Ting, Catalano, Carlos Enrique, Huffman, Jamie B, Homa, Fred L, Evilevitch, Alex

“…Herpes simplex type 1 virus (HSV-1) and bacteriophage λ capsids undergo considerable structural changes during self-assembly and DNA packaging. The initial…”
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Thermodynamic Interrogation of the Assembly of a Viral Genome Packaging Motor Complex by Yang, Teng-Chieh, Ortiz, David, Nosaka, Lyn’Al, Lander, Gabriel C., Catalano, Carlos Enrique

“…Viral terminase enzymes serve as genome packaging motors in many complex double-stranded DNA viruses. The functional motors are multiprotein complexes that…”
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Biochemical Characterization of Bacteriophage Lambda Genome Packaging in Vitro by Yang, Qin, Catalano, Carlos Enrique

“…Bacteriophage λ has been extensively studied, and the abundance of genetic and biochemical information available makes this an ideal model system to study…”
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Domain Structure of gpNu1, a Phage Lambda DNA Packaging Protein by Yang, Qin, Berton, Nancy, Manning, Mark C, Catalano, Carlos Enrique

“…The terminase enzyme from bacteriophage lambda is responsible for the insertion of a dsDNA genome into the confines of the viral capsid. The holoenzyme is…”
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Assembly of a Nucleoprotein Complex Required for DNA Packaging by Bacteriophage λ by Yang, Qin, Hanagan, Adrienne, Catalano, Carlos Enrique

“…A critical step in the assembly of bacteriophage λ is the excision of a single genome from a concatemeric DNA precursor and insertion of genomic DNA into an…”
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Binding then bending: A mechanism for wrapping DNA by Khrapunov, Sergei, Brenowitz, Michael, Rice, Phoebe A, Catalano, Carlos Enrique

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Kinetic Characterization of the GTPase Activity of Phage λ Terminase:  Evidence for Communication between the Two “NTPase” Catalytic Sites of the Enzyme by Woods, Liping, Catalano, Carlos Enrique

“… We have previously characterized the ATPase activity of the holoenzyme and have identified catalytic active sites in each enzyme subunit [Tomka and Catalano (1993…”
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Thermodynamic Characterization of Viral Procapsid Expansion into a Functional Capsid Shell by Medina, Elizabeth, Nakatani, Eri, Kruse, Shannon, Catalano, Carlos Enrique

“…The assembly of “complex” DNA viruses such as the herpesviruses and many tailed bacteriophages includes a DNA packaging step where the viral genome is inserted…”
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Analytical Ultracentrifugation as a Tool to Study Nonspecific Protein-DNA Interactions by Yang, Teng-Chieh, Catalano, Carlos Enrique, Maluf, Nasib Karl

“…Analytical ultracentrifugation (AUC) is a powerful tool that can provide thermodynamic information on associating systems. Here, we discuss how to use the two…”
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Challenging Packaging Limits and Infectivity of Phage λ by Nurmemmedov, Elmar, Castelnovo, Martin, Medina, Elizabeth, Catalano, Carlos Enrique, Evilevitch, Alex

“…The terminase motors of bacteriophages have been shown to be among the strongest active machines in the biomolecular world, being able to package several tens…”
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Kinetic Characterization of the Strand Separation (“Helicase”) Activity of the DNA Packaging Enzyme from Bacteriophage λ by Yang, Qin, Catalano, Carlos Enrique

“… We have previously characterized the endonuclease [Tomka, M. A., & Catalano, C. E. (1993) J. Biol. Chem. 268, 3056−3065] and ATPase [Tomka, M. A., & Catalano, C. E. (1993) Biochemistry 32, 11992…”
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Integration Host Factor Assembly at the Cohesive End Site of the Bacteriophage Lambda Genome: Implications for Viral DNA Packaging and Bacterial Gene Regulation by Sanyal, Saurarshi J., Yang, Teng-Chieh, Catalano, Carlos Enrique

“…Integration host factor (IHF) is an Escherichia coli protein involved in (i) condensation of the bacterial nucleoid and (ii) regulation of a variety of…”
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The Enzymology of a Viral Genome Packaging Motor Is Influenced by the Assembly State of the Motor Subunits by Andrews, Benjamin T, Catalano, Carlos Enrique

“…Terminase enzymes are responsible for the excision of a single genome from a concatemeric precursor (genome maturation) and concomitant packaging of DNA into…”
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Assembly and Maturation of the Bacteriophage Lambda Procapsid: gpC Is the Viral Protease by Medina, Elizabeth, Wieczorek, Doug, Medina, Eva Margarita, Yang, Qin, Feiss, Michael, Catalano, Carlos Enrique

“…Viral capsids are robust structures designed to protect the genome from environmental insults and deliver it to the host cell. The developmental pathway for…”
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A Minimal Kinetic Model for a Viral DNA Packaging Machine by Yang, Qin, Catalano, Carlos Enrique

“…Terminase enzymes are common to both eukaryotic and prokaryotic double-stranded DNA viruses. These enzymes possess ATPase and nuclease activities that work in…”
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Kinetic characterization of the ATPase activity of the DNA packaging enzyme from bacteriophage .lambda by Tomka, Mary Ann, Catalano, Carlos Enrique

“… We have previously characterized the endonuclease activity of purified terminase from bacteriophage lambda [Tomka, M. A., & Catalano, C. E. (1993) J. Biol. Chem. 268, 3056-3065…”
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Cloning, Expression, and Biochemical Characterization of Hexahistidine-tagged Terminase Proteins by Hang, Qi, Woods, Liping, Feiss, Michael, Catalano, Carlos Enrique

“…The terminase enzyme from bacteriophage λ is composed of two viral proteins (gpA, 73.2 kDa; gpNu1, 20.4 kDa) and is responsible for packaging viral DNA into…”
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Assembly and characterization of gp160-nanodiscs: A new platform for biochemical characterization of HIV envelope spikes by Nakatani-Webster, Eri, Hu, Shiu-Lok, Atkins, William M., Catalano, Carlos Enrique

“…•Lipid nanodiscs containing full-length glycoslyated gp160 Env proteins are prepared.•The particles are soluble and homogeneous compared to…”
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Packaging of a Unit-Length Viral Genome: The Role of Nucleotides and the gpD Decoration Protein in Stable Nucleocapsid Assembly in Bacteriophage λ by Yang, Qin, Maluf, Nasib Karl, Catalano, Carlos Enrique

“…The developmental pathways for a variety of eukaryotic and prokaryotic double-stranded DNA viruses include packaging of viral DNA into a preformed procapsid…”
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