Search Results - Bradesi, S

Role of spinal cord glia in the central processing of peripheral pain perception by Bradesi, S.

“…Background  The discovery that glial activation plays a critical role in the modulation of neuronal functions and affects the spinal processing of nociceptive…”
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Functional GI disorders: from animal models to drug development by Mayer, E A, Bradesi, S, Chang, L, Spiegel, B M R, Bueller, J A, Naliboff, B D

“…Despite considerable efforts by academic researchers and by the pharmaceutical industry, the development of novel pharmacological treatments for irritable…”
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Guanylate cyclase C‐mediated antinociceptive effects of linaclotide in rodent models of visceral pain by Eutamene, H., Bradesi, S., Larauche, M., Theodorou, V., Beaufrand, C., Ohning, G., Fioramonti, J., Cohen, M., Bryant, A. P., Kurtz, C., Currie, M. G., Mayer, E. A., Bueno, L.

“…Background  Linaclotide is a novel, orally administered investigational drug currently in clinical development for the treatment of constipation‐predominant…”
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Review article: modulation of the brain–gut axis as a therapeutic approach in gastrointestinal disease by MAYER, E. A., TILLISCH, K., BRADESI, S.

“…Summary Background The importance of bi‐directional brain‐gut interactions in gastrointestinal illness is increasingly being recognized, most prominently in…”
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Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase by Ait-Belgnaoui, Afifa, Bradesi, Sylvie, Fioramonti, Jean, Theodorou, Vassilia, Bueno, Lionel

“…Hypersensitivity to rectal or colonic distension characterizes most patients with IBS and increased gut permeability has been described in post-dysenteric IBS…”
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PAR4: A new role in the modulation of visceral nociception by Bradesi, S.

“…Protease‐activated receptors (PARs) are a family of G‐protein‐coupled receptors with a widespread distribution that are involved in various physiological…”
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Guaianolide Derivatives from the Invasive Xanthium spinosum L.: Evaluation of Their Allelopathic Potential by Baldi, Sylvain, Bradesi, Pascale, Muselli, Alain

“…Ziniolide, xantholide B (11α-dihydroziniolide), and 11β-dihydroziniolide, three sesquiterpene lactones with 12,8-guaianolide skeletons, were identified as…”
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Gut microbiota and neurogastroenterology and motility: the good the bad and the ugly by Farrugia, G., Simren, M., Mawe, G., Bradesi, S., Bredenoord, A. J.

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Neurogastroenterology and Motility going online only in January 2014 by Farrugia, G., Mawe, G., Simren, M., Bradesi, S., Bredenoord, A.

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S1055 Burden of Bowel Urgency Among Pediatric Patients With Ulcerative Colitis: Results From a Physician and Patient Survey by Chavannes, Mallory, Gibble, Theresa Hunter, Knight, Hannah, Palace, Vanda, Barlow, Sophie, Bradesi, Sylvie, Rawal, Hemangi N., Komocsar, Wendy J.

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Guaianolide Derivatives from the Invasive IXanthium spinosum/I L.: Evaluation of Their Allelopathic Potential by Baldi, Sylvain, Bradesi, Pascale, Muselli, Alain

“…Ziniolide, xantholide B (11α-dihydroziniolide), and 11β-dihydroziniolide, three sesquiterpene lactones with 12,8-guaianolide skeletons, were identified as…”
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Chronic psychological stress in high-anxiety rats induces sustained bladder hyperalgesia by Lee, Una J, Ackerman, A. Lenore, Wu, Ais, Zhang, Rong, Leung, Joanne, Bradesi, Sylvie, Mayer, Emeran A, Rodríguez, Larissa V

“…Abstract Objective To evaluate whether anxiety-prone rats exposed to chronic water avoidance stress (WAS) develop visceral bladder hyperalgesia in addition to…”
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S752 Biomarkers and Bowel Urgency in Response to Mirikizumab for Ulcerative Colitis by Dubinsky, Marla C., Naegeli, April N., Shan, Mingyang, Kayhan, Cem, Milch, Catherine, Schmitz, Jochen, Bradesi, Sylvie, Travis, Simon

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Acute and chronic stress differently affect visceral sensitivity to rectal distension in female rats by BRADESI, S., EUTAMENE, H., GARCIA‐VILLAR, R., FIORAMONTI, J., BUÉNO, L.

“…Stressful life events are frequently associated with outward signs of irritable bowel syndrome (IBS). Increasing evidence suggests that acute and chronic…”
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Stress-induced visceral hypersensitivity in female rats is estrogen-dependent and involves tachykinin NK1 receptors by Bradesi, Sylvie, Eutamene, Helene, Garcia-Villar, Rafael, Fioramonti, Jean, Bueno, Lionel

“…Hormonal cycling may be related to a higher incidence of pain syndrome in female. As tachykinins are pivotal in stress-induced colonic dysfunction, we…”
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The Effects of Acute and Chronic Psychological Stress on Bladder Function in a Rodent Model by Smith, Ariana L, Leung, Joanne, Kun, Suny, Zhang, Rong, Karagiannides, Iordanes, Raz, Shlomo, Lee, Una, Golovatscka, Viktoriya, Pothoulakis, Charalabos, Bradesi, Sylvie, Mayer, Emeran A, Rodríguez, Larissa V

“…Objective Psychological stress plays a role in the exacerbation of functional lower urinary tract disorders, such as painful bladder syndrome and overactive…”
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Mechanistic understanding of the effects of probiotics in the modulation of abdominal pain: one study at a time by Bradesi, Sylvie

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Acute restraint stress activates functional NK1 receptor in the colon of female rats: involvement of steroids by Bradesi, S, Eutamene, H, Fioramonti, J, Bueno, L

“…Background and aims: Psychological factors have been implicated in the aetiology of irritable bowel syndrome characterised by intestinal altered motility and…”
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Role of spinal cord glia in the central processing of peripheral pain perception: Spinal glia and pain processing by Bradesi, S.

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Corticotropin-releasing factor type 1 receptors mediate the visceral hyperalgesia induced by repeated psychological stress in rats by Larauche, Muriel, Bradesi, Sylvie, Million, Mulugeta, McLean, Peter, Taché, Yvette, Mayer, Emeran A, McRoberts, James A

“…Visceral hypersensitivity has been implicated as an important pathophysiological mechanism in functional gastrointestinal disorders. In this study, we…”
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