Search Results - BioMed Central

2020 WHO guidelines on physical activity and sedentary behaviour for children and adolescents aged 5-17 years: summary of the evidence by Chaput, Jean-Philippe, Willumsen, Juana, Bull, Fiona, Chou, Roger, Ekelund, Ulf, Firth, Joseph, Jago, Russell, Ortega, Francisco B, Katzmarzyk, Peter T

“…The World Health Organization (WHO) released in 2020 updated global guidelines on physical activity and sedentary behaviour for children, adolescents, adults,…”
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Sample size used to validate a scale: a review of publications on newly-developed patient reported outcomes measures by Anthoine, Emmanuelle, Moret, Leïla, Regnault, Antoine, Sébille, Véronique, Hardouin, Jean-Benoit

“…New patient reported outcome (PRO) measures are regularly developed to assess various aspects of the patients' perspective on their disease and treatment. For…”
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Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement by Moher, David, Shamseer, Larissa, Clarke, Mike, Ghersi, Davina, Liberati, Alessandro, Petticrew, Mark, Shekelle, Paul, Stewart, Lesley A

“…Systematic reviews should build on a protocol that describes the rationale, hypothesis, and planned methods of the review; few reviews report whether a…”
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The Ensembl Variant Effect Predictor by McLaren, William, Gil, Laurent, Hunt, Sarah E, Riat, Harpreet Singh, Ritchie, Graham R S, Thormann, Anja, Flicek, Paul, Cunningham, Fiona

“…The Ensembl Variant Effect Predictor is a powerful toolset for the analysis, annotation, and prioritization of genomic variants in coding and non-coding…”
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MOFA+: a statistical framework for comprehensive integration of multi-modal single-cell data by Argelaguet, Ricard, Arnol, Damien, Bredikhin, Danila, Deloro, Yonatan, Velten, Britta, Marioni, John C, Stegle, Oliver

“…Technological advances have enabled the profiling of multiple molecular layers at single-cell resolution, assaying cells from multiple samples or conditions…”
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Comprehensive analyses of tumor immunity: implications for cancer immunotherapy by Li, Bo, Severson, Eric, Pignon, Jean-Christophe, Zhao, Haoquan, Li, Taiwen, Novak, Jesse, Jiang, Peng, Shen, Hui, Aster, Jon C, Rodig, Scott, Signoretti, Sabina, Liu, Jun S, Liu, X Shirley

“…Understanding the interactions between tumor and the host immune system is critical to finding prognostic biomarkers, reducing drug resistance, and developing…”
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Mash: fast genome and metagenome distance estimation using MinHash by Ondov, Brian D, Treangen, Todd J, Melsted, Páll, Mallonee, Adam B, Bergman, Nicholas H, Koren, Sergey, Phillippy, Adam M

“…Mash extends the MinHash dimensionality-reduction technique to include a pairwise mutation distance and P value significance test, enabling the efficient…”
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A survey of best practices for RNA-seq data analysis by Conesa, Ana, Madrigal, Pedro, Tarazona, Sonia, Gomez-Cabrero, David, Cervera, Alejandra, McPherson, Andrew, Szcześniak, Michał Wojciech, Gaffney, Daniel J, Elo, Laura L, Zhang, Xuegong, Mortazavi, Ali

“…RNA-sequencing (RNA-seq) has a wide variety of applications, but no single analysis pipeline can be used in all cases. We review all of the major steps in…”
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Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR by Haeussler, Maximilian, Schönig, Kai, Eckert, Hélène, Eschstruth, Alexis, Mianné, Joffrey, Renaud, Jean-Baptiste, Schneider-Maunoury, Sylvie, Shkumatava, Alena, Teboul, Lydia, Kent, Jim, Joly, Jean-Stephane, Concordet, Jean-Paul

“…The success of the CRISPR/Cas9 genome editing technique depends on the choice of the guide RNA sequence, which is facilitated by various websites. Despite the…”
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 by Love, Michael I, Huber, Wolfgang, Anders, Simon

“…In comparative high-throughput sequencing assays, a fundamental task is the analysis of count data, such as read counts per gene in RNA-seq, for evidence of…”
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The global distribution of acute unintentional pesticide poisoning: estimations based on a systematic review by Boedeker, Wolfgang, Watts, Meriel, Clausing, Peter, Marquez, Emily

“…Human poisoning by pesticides has long been seen as a severe public health problem. As early as 1990, a task force of the World Health Organization (WHO)…”
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RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3 by Niu, Yi, Lin, Ziyou, Wan, Arabella, Chen, Honglei, Liang, Heng, Sun, Lei, Wang, Yuan, Li, Xi, Xiong, Xiao-Feng, Wei, Bo, Wu, Xiaobin, Wan, Guohui

“…N6-methyladenosine (m6A) modification is the most pervasive modification in mRNA, and has been considered as a new layer of epigenetic regulation on mRNA…”
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CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq by Hashimshony, Tamar, Senderovich, Naftalie, Avital, Gal, Klochendler, Agnes, de Leeuw, Yaron, Anavy, Leon, Gennert, Dave, Li, Shuqiang, Livak, Kenneth J, Rozenblatt-Rosen, Orit, Dor, Yuval, Regev, Aviv, Yanai, Itai

“…Single-cell transcriptomics requires a method that is sensitive, accurate, and reproducible. Here, we present CEL-Seq2, a modified version of our CEL-Seq…”
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Pooling across cells to normalize single-cell RNA sequencing data with many zero counts by Lun, Aaron T L, Bach, Karsten, Marioni, John C

“…Normalization of single-cell RNA sequencing data is necessary to eliminate cell-specific biases prior to downstream analyses. However, this is not…”
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Reference ranges ("normal values") for cardiovascular magnetic resonance (CMR) in adults and children: 2020 update by Kawel-Boehm, Nadine, Hetzel, Scott J, Ambale-Venkatesh, Bharath, Captur, Gabriella, Francois, Christopher J, Jerosch-Herold, Michael, Salerno, Michael, Teague, Shawn D, Valsangiacomo-Buechel, Emanuela, van der Geest, Rob J, Bluemke, David A

“…Cardiovascular magnetic resonance (CMR) enables assessment and quantification of morphological and functional parameters of the heart, including chamber size…”
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Synovitis in osteoarthritis: current understanding with therapeutic implications by Mathiessen, Alexander, Conaghan, Philip G

“…Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging phenotypes demonstrating complex and multi-tissue pathologies involving…”
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Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin by Bokulich, Nicholas A, Kaehler, Benjamin D, Rideout, Jai Ram, Dillon, Matthew, Bolyen, Evan, Knight, Rob, Huttley, Gavin A, Gregory Caporaso, J

“…Taxonomic classification of marker-gene sequences is an important step in microbiome analysis. We present q2-feature-classifier (…”
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Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects by Javed, Rabia, Zia, Muhammad, Naz, Sania, Aisida, Samson O, Ain, Noor ul, Ao, Qiang

“…Abstract Capping agents are of utmost importance as stabilizers that inhibit the over-growth of nanoparticles and prevent their aggregation/coagulation in…”
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JBrowse: a dynamic web platform for genome visualization and analysis by Buels, Robert, Yao, Eric, Diesh, Colin M, Hayes, Richard D, Munoz-Torres, Monica, Helt, Gregg, Goodstein, David M, Elsik, Christine G, Lewis, Suzanna E, Stein, Lincoln, Holmes, Ian H

“…JBrowse is a fast and full-featured genome browser built with JavaScript and HTML5. It is easily embedded into websites or apps but can also be served as a…”
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jvenn: an interactive Venn diagram viewer by Bardou, Philippe, Mariette, Jérôme, Escudié, Frédéric, Djemiel, Christophe, Klopp, Christophe

“…Venn diagrams are commonly used to display list comparison. In biology, they are widely used to show the differences between gene lists originating from…”
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