Search Results - BRUGAROLAS, ANTONIO

RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer by Manzano, Ramon Gonzalez, Catalan-Latorre, Ana, Brugarolas, Antonio

“…Muscle invasive urothelial bladder carcinoma (MIBC) present RB1 and TP53 somatic alterations in a variable percentage of tumors throughout all molecular…”
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Psycho-Oncological Intervention Through Counseling in Patients With Differentiated Thyroid Cancer in Treatment With Radioiodine (COUNTHY, NCT05054634): A Non-randomized Controlled Study by Javaloyes, Nuria, Crespo, Aurora, Redal, M Carmen, Brugarolas, Antonio, Botella, Lara, Escudero-Ortiz, Vanesa, Sureda, Manuel

“…Diagnosis and treatment of differentiated thyroid carcinomas (DTC) cause anxiety and depression. Additionally, these patients suffer hormonal alterations that…”
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Relevance of Fc Gamma Receptor Polymorphisms in Cancer Therapy With Monoclonal Antibodies by Mata-Molanes, Juan J., Rebollo-Liceaga, Joseba, Martínez-Navarro, Elena Mª, Manzano, Ramón González, Brugarolas, Antonio, Juan, Manel, Sureda, Manuel

“…Therapeutic monoclonal antibodies (mAbs), including immune checkpoint inhibitors (ICIs), are an important breakthrough for the treatment of cancer and have…”
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Polymorphisms of the Repeated Sequences in the Enhancer Region of the Thymidylate Synthase Gene Promoter May Predict Downstaging After Preoperative Chemoradiation in Rectal Cancer by VILLAFRANCA, Elena, OKRUZHNOV, Yury, ANGELETTI, Silvia, BRUGAROLAS, Antonio, DOMINGUEZ, Miguel A, GARCIA-FONCILLAS, Jesus, AZINOVIC, Ignacio, MARTINEZ, Enrique, ILLARRAMENDI, Jose J, ARIAS, Fernando, MARTINEZ MONGE, Rafael, SALGADO, Esteban

“…Thymidylate synthase (TS) is an important target enzyme for the fluoropyrimidines. TS gene promoter possesses regulatory tandemly repeated (TR) sequences that…”
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Therapeutic Drug Monitoring of Erlotinib in Non-Small Cell Lung Carcinoma: A Case Study by Catalán-Latorre, Ana, Sureda, Manuel, Brugarolas-Masllorens, Antonio, Escudero-Ortiz, Vanesa

“…We describe a clinical case of an 84-year-old man diagnosed with non-small cell lung carcinoma and epidermal growth factor receptor mutation, who was treated…”
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Therapeutic drug monitoring of nivolumab in clinical practice: Preliminary experience by Sureda, Manuel, Catalán-Latorre, Ana, Mata, Juan José, Escudero, Vanesa, Brugarolas, Antonio

“…Abstract only e14089 Background: Fixed dose schemes, regardless of body weight, have been accepted by the regulatory agencies for the PD-1 targeting…”
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A novel genomic signature predicting FDG uptake in diverse metastatic tumors by Crespo-Jara, Aurora, Redal-Peña, Maria Carmen, Martinez-Navarro, Elena Maria, Sureda, Manuel, Fernandez-Morejon, Francisco Jose, Garcia-Cases, Francisco J., Manzano, Ramon Gonzalez, Brugarolas, Antonio

“…Background Building a universal genomic signature predicting the intensity of FDG uptake in diverse metastatic tumors may allow us to understand better the…”
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Therapeutic Drug Monitoring of Erlotinib in Non-Small Cell Lung Carcinoma: A Case Study by Ana, Catalán-Latorre, Manuel, Sureda, Antonio, Brugarolas-Masllorens, Vanesa, Escudero-Ortiz

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Therapeutic drug monitoring (TDM) of tyrosine kinase inhibitors (TKI) in routine practice in an oncology service. preliminary results by Sureda, Manuel, Dominguez, Vanessa, Escudero, Vanesa, Brugarolas, Antonio

“…Abstract only…”
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A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs by Crespo-Jara, Aurora, González Manzano, Ramón, Lopera Sierra, Maribel, Redal Peña, María Carmen, Brugarolas Masllorens, Antonio

“…ABSTRACTWe present a sarcoma patient with a tumor reduction of more than 50% in lung metastasis after 2 single courses of the investigational medical product…”
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Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain by Navarro, Gemma, Cordomi, Arnau, Brugarolas, Marc, Moreno, Estefania, Aguinaga, David, Pnrez-Benito, Laura, Ferre, Sergi, Cortns, Antoni, Casado, Vicent, Mallol, Josefa, Canela, Enric I, Lluis, Carme, Pardo, Leonardo, McCormick, Peter J, Franco, Rafael

“…BACKGROUNDG-protein-coupled receptor (GPCR) heteromeric complexes have distinct properties from homomeric GPCRs, giving rise to new receptor functionalities…”
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Front-line paclitaxel/cisplatin-based chemotherapy in brain metastases from non-small-cell lung cancer by Cortes, Javier, Rodriguez, Javier, Aramendia, Jose Manuel, Salgado, Esteban, Gurpide, Alfonso, Garcia-Foncillas, Jesus, Aristu, Jose Javier, Claver, Angela, Bosch, Ana, Lopez-Picazo, Jose Maria, Martin-Algarra, Salvador, Brugarolas, Antonio, Calvo, Emiliano

“…Paclitaxel-cisplatin is considered to be a standard therapy for metastatic non-small-cell lung cancer (NSCLC). The aim of this study was to evaluate the…”
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Immunological profile could be responsible of the unusual long-lasting cutaneous-only breast cancer recurrence: An observational study by Rebollo, Joseba, González-Manzano, Ramón, Sureda, Manuel, Martínez, Elena Ma, Monedero, Elena, Bretcha, Pedro, Brugarolas, Antonio

“…e13000 Background: A small number of breast cancer patients develops long-lasting loco-regional cutaneous recurrent disease with a delayed appearance of…”
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Colorectal Carcinomas and PTEN/MMAC1 Gene Mutations by DICUONZO, Giordano, ANGELETTI, Silvia, GARCIA-FONCILLAS, Jesus, BRUGAROLAS, Antonio, OKROUZHNOV, Yuri, SANTINI, Daniele, TONINI, Giuseppe, LORINO, Giulia, DE CESARIS, Marina, BALDI, Alfonso

“…Purpose: PTEN/MMAC1/TEP1 is a tumor suppressor gene encoding a dual-specificity protein phosphatase with homology to the cytoskeleton proteins, chicken tensin…”
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Abstract 4648: Development and validation of an HPLC-UV method for Sirolimus (sir) quantification in human blood and application to cancer patients in routine clinical practice by Escudero-Ortiz, Vanesa, Valenzuela, Belen, Rebollo, Joseba, Sureda, Manuel, Brugarolas, Antonio

“…Background and objective: After oral administration, SIR (mTOR inhibitor) is rapid absorbed with a bioavailability around 14%. SIR is distributed mostly into…”
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Equilibrative Nucleoside Transporter ENT1 as a Biomarker of Huntington Disease by Guitart, Xavier, Bonaventura, Jordi, Rea, William, Orrú, Marco, Cellai, Lucrezia, Dettori, Ilaria, Pedata, Felicita, Brugarolas, Marc, Cortés, Antonio, Casadó, Vicent, Chang, Ching-Pang, Narayanan, Manikandan, Chern, Yijuang, Ferré, Sergi

“…Abstract The initial goal of this study was to investigate alterations in adenosine A2A receptor (A2A R) density or function in a rat model of Huntington…”
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FEASIBILITY OF REPEAT SENTINEL NODE BIOPSY (r-SNB) IN IPSILATERAL RELAPSED BREAST CANCER AFTER MASTECTOMY AND SNB: CASE REPORT AND LITERATURE REVIEW by Yáñez, Alejandro Paz, Diaz, Rodolfo Martín, Muñoz, Paula Muñoz, Ortega Ramírez, Jose Rolando, Boix, Pedro Bretcha, Masllorens, Antonio Brugarolas

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Abstract 762: Therapeutic drug monitoring of Anthracyclines and Taxanes in chemotherapy of breast cancer patients by Valenzuela, Belén, Escudero, Vanesa, Rebollo, Joseba, Sureda, Manuel, Brugarolas, Antonio

“…Background: Anthracyclines (A) and Taxanes (T) remain amongst the most active drugs in breast cancer chemotherapy. However, significant toxicities are…”
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Transcriptome (RNA next generation sequencing) for personalizing of cancer treatment: A correlation with previous clinical resistance by Sureda, Manuel, Rebollo, Joseba, González-Manzano, Ramón, Martínez, Elena Ma, Rostagno, Roman, Mata, Juan José, Monedero, Elena, Ortega, Jose, Brugarolas, Antonio

“…Abstract only e15046 Background: RNA Next Generation Sequencing (transcriptome) is a potential useful tool to predict chemoresistance to available anticancer…”
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A phase II study of Recchia's immunomodulatory schedule (RIS) as a maintenance therapy in high-risk tumors after a response by Sureda, Manuel, Rebollo, Joseba, Vazquez, Begona, Bretcha, Pere, Cañon, Rosa, Duarte, Maritza, Munoz, Vicente, Brugarolas, Antonio

“…Abstract only 3074 Background: F. Recchia et al. (Interleukin-2 and 13-cis retinoic acid in the treatment of minimal residual disease: A phase II study. Int J…”
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