Search Results - BMC

CUT RUNTools: a flexible pipeline for CUT RUN processing and footprint analysis by Qian Zhu, Nan Liu, Stuart H. Orkin, Guo-Cheng Yuan

“…Abstract We introduce CUT&RUNTools as a flexible, general pipeline for facilitating the identification of chromatin-associated protein binding and genomic…”
Get full text

P soralea corylifolia L.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics by Lele Chen, Shuguang Chen, Peng Sun, Xinyue Liu, Zhaoshuang Zhan, Jiafeng Wang

“…Abstract Psoralea corylifolia L. (PCL), referred to as “Bu-gu-zhi” in Chinese, has great medicinal values since ancient times. PCL is the dried ripe fruit of…”
Get full text

Prevalence and distribution of bla CTX-M, bla SHV, bla TEM genes in extended- spectrum β- lactamase- producing E. coli isolates from broiler farms in the Philippines by Romeo S. Gundran, Paul A. Cardenio, Marvin A. Villanueva, Fredelon B. Sison, Carolyn C. Benigno, Kwanchai Kreausukon, Duangporn Pichpol, Veerasak Punyapornwithaya

“…Abstract Background Antimicrobial resistance is a worldwide problem causing serious health threats. Escherichia coli is one of the most important bacteria that…”
Get full text

Introducing the f 0% method: a reliable and accurate approach for qPCR analysis by Mahmoud Gamal, Marwa A. Ibrahim

“…Abstract Background qPCR is a widely used technique in scientific research as a basic tool in gene expression analysis. Classically, the quantitative endpoint…”
Get full text

Mining contextually meaningful subgraphs from a vertex-attributed graph by Hakim, Riyad, Salem, Saeed

“…Networks have emerged as a natural data structure to represent relations among entities. Proteins interact to carry out cellular functions and protein-Protein…”
Get full text

Rapidly disseminating bla OXA-232 carrying Klebsiella pneumoniae belonging to ST231 in India: multiple and varied mobile genetic elements by Chaitra Shankar, Purva Mathur, Manigandan Venkatesan, Agila Kumari Pragasam, Shalini Anandan, Surbhi Khurana, Balaji Veeraraghavan

“…Abstract Background Recently, in India, there has been a shift from NDM to OXA48-like carbapenemases. OXA-181 and OXA-232 are the frequently produced variants…”
Get full text

Carriage of distinct bla KPC-2 and bla OXA-48 plasmids in a single ST11 hypervirulent Klebsiella pneumoniae isolate in Egypt by Yanxian Yang, Yongqiang Yang, Mohamed Abd El-Gawad El-Sayed Ahmed, Mingyang Qin, Ruowen He, Yiping Wu, Xiaoxue Liang, Lan-Lan Zhong, Ping Chen, Baoguo Deng, Reem Mostafa Hassan, Weihong Wen, Lingqing Xu, Xubin Huang, Lin Xu, Guo-Bao Tian

“…Abstract Background Carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKP) causes serious infections with significant morbidity and mortality. However, the…”
Get full text

Emergence of carbapenem-resistant and colistin-susceptible Enterobacter cloacae complex co-harboring bla IMP-1 and mcr-9 in Japan by Pegah Kananizadeh, Satoshi Oshiro, Shin Watanabe, Shu Iwata, Kyoko Kuwahara-Arai, Masahiro Shimojima, Miho Ogawa, Tatsuya Tada, Teruo Kirikae

“…Abstract Background The spread of Enterobacteriaceae producing both carbapenemases and Mcr, encoded by plasmid-mediated colistin resistance genes, has become a…”
Get full text

Graph regularized L 2,1-nonnegative matrix factorization for miRNA-disease association prediction by Zhen Gao, Yu-Tian Wang, Qing-Wen Wu, Jian-Cheng Ni, Chun-Hou Zheng

“…Abstract Background The aberrant expression of microRNAs is closely connected to the occurrence and development of a great deal of human diseases. To study…”
Get full text

The overall regulatory network and contributions of ABC(D)E model genes in yellowhorn flower development by Wang, Hanhui, Lu, Yanan, Zhang, Yanru, Liu, Guan, Yu, Song, Zheng, Zhimin

“…Single flowers and double flowers, exhibiting distinct flower morphologies, developmental process and regulatory networks, have garnered significant attention…”
Get full text

Complete-genome sequencing and comparative genomic characterization of bla NDM-5 carrying Citrobacter freundii isolates from a patient with multiple infections by Jianzhong Ye, Lulu Jin, Yaling Li, Hao Xu, Yishuai Lin, Tieli Zhou, Beiwen Zheng, Maofeng Wang, Zhongyong Wang

“…Abstract Background The emergence and wide spread of carbapenemase-producing Enterobacteriaceae (CPE) poses a growing threat to global public health. However,…”
Get full text

Correction: Programmed death receptor (PD-)1/PD-ligand (L)1 in urological cancers: the "all-around warrior" in immunotherapy by Liu, Qiang, Guan, Yujing, Li, Shenglong

Get full text

Assessment of Bla TEM, Bla SHV, and Bla CTX-M genes of antibiotic resistance in Gram-negative bacilli causing urinary tract infections in Khartoum State: a cross-sectional study by Manal Ismail Abdalla Mohammedkheir, Elsheikh Mahgoub Gaafar, Eltayeb GareebAlla Eltayeb AbdAlla

“…Abstract Background Gram-negative bacilli are the most common etiological agents responsible for urinary tract infections. The prevalence of antibiotic…”
Get full text

Identification and functional analysis of GmPsaL regulating pod color in vegetable soybean by Dai, Dongqing, Huang, Lu, Zhang, Xiaoyan, Zhang, Shiqi, Liu, Jinyang, Yuan, Xingxing, Chen, Xin, Xue, Chenchen

“…Abstract Background Vegetable soybean is rich in nutrients and has a unique flavor. It is highly preferred by people because of its pharmacological activities,…”
Get full text

T4Seeker: a hybrid model for type IV secretion effectors identification by Li, Jing, He, Shida, Zhang, Jian, Zhang, Feng, Zou, Quan, Ni, Fengming

“…The type IV secretion system is widely present in various bacteria, such as Salmonella, Escherichia coli, and Helicobacter pylori. These bacteria use the type…”
Get full text

Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway by Tang, Yue, Dong, Ming-Hao, Pang, Xiao-Wei, Zhang, Hang, Chu, Yun-Hui, Zhou, Luo-Qi, Yang, Sheng, Zhang, Lu-Yang, You, Yun-Fan, Zhu, Li-Fang, Wang, Wei, Qin, Chuan, Tian, Dai-Shi

“…Circulating miR-30c-2-3p has been closely related to vascular diseases, however, its role and underlying mechanisms in ischemic stroke remained unclear. Our…”
Get full text

High-fat diet increases gliosis and immediate early gene expression in APOE 3 mice, but not APOE4 mice by Nahdia S. Jones, Katarina Q. Watson, G. William Rebeck

“…Abstract Background APOE 4 is the strongest genetic risk factor for Alzheimer’s disease (AD), and obesity is a strong environmental risk factor for AD. These…”
Get full text

Letter: The risk-benefit balance of CRISPR-Cas screening systems in gene editing and targeted cancer therapy by Yi, Qiang, Ouyang, Xinting, Zhu, Gangfeng, Zhong, Jinghua

Get full text

A multispecies outbreak of carbapenem-resistant bacteria harboring the bla KPC gene in a non-classical transposon element by Aniela Wozniak, Cristian Figueroa, Francisco Moya-Flores, Piero Guggiana, Claudia Castillo, Lina Rivas, José M. Munita, Patricia C. García

“…Abstract Background Klebsiella pneumoniae is the most frequent KPC-producing bacteria. The bla KPC gene is frequently embedded in Tn4401 transposon, and less…”
Get full text

Evaluating the implementation of the National Primary Health Care Development Agency (NPHCDA) gateway for the Basic Healthcare Provision Fund (BHCPF) across six Northern states in Nigeria by Igbokwe, Uchenna, Ibrahim, Raihanah, Aina, Muyi, Umar, Musa, Salihu, Muhammed, Omoregie, Efosa, Sadiq, Firdausi Umar, Obonyo, Benson, Muhammad, Rilwanu, Isah, Salisu Idris, Joseph, Natsah, Wakil, Babagana, Tijjani, Faruk, Ibrahim, Abubakar, Yahaya, Mohammed Nura, Aigbogun, Eric

“…Abstract Background This evaluation research utilized both qualitative and quantitative methods to assess the implementation of the National Primary Health…”
Get full text