Search Results - "wang, Qixue"

Long Noncoding RNA NEAT1 , Regulated by the EGFR Pathway, Contributes to Glioblastoma Progression Through the WNT/ β -Catenin Pathway by Scaffolding EZH2 by Chen, Qun, Cai, Jinquan, Wang, Qixue, Wang, Yunfei, Liu, Mingyang, Yang, Jingxuan, Zhou, Junhu, Kang, Chunsheng, Li, Min, Jiang, Chuanlu

“…Long noncoding RNAs have been implicated in gliomagenesis, but their mechanisms of action are mainly undocumented. Through public glioma mRNA expression data…”
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FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury by Cai, Ying, Yang, Eryan, Yao, Xiuhua, Zhang, Xuebin, Wang, Qixue, Wang, Yunfei, Liu, Ji, Fan, Weijia, Yi, Kaikai, Kang, Chunsheng, Wu, Jialing

“…Autophagy of mitochondria, termed mitophagy, plays an important role in cerebral ischemia-reperfusion (IR) injury, but the mechanism is not yet clear…”
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Energy metabolism in major depressive disorder: Recent advances from omics technologies and imaging by Gu, Xinyi, Ke, Shuang, Wang, Qixue, Zhuang, Tongxi, Xia, Chenyi, Xu, Ying, Yang, Li, Zhou, Mingmei

“…Major depressive disorder (MDD) is a serious psychiatric disorder that associated with high rate of disability and increasing suicide rate, and the…”
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The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells by Wang, Qixue, Liu, Xing, Zhou, Junhu, Yang, Chao, Wang, Guangxiu, Tan, Yanli, Wu, Ye, Zhang, Sijing, Yi, Kaikai, Kang, Chunsheng

“…RNA is rarely used as a therapeutic target due to its flexible structure and instability. CRISPR‐Cas13a is a powerful tool for RNA knockdown, and the potential…”
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Putting Proteomics Into Immunotherapy for Glioblastoma by Chen, Liangyu, Qin, Di, Guo, Xinyu, Wang, Qixue, Li, Jie

“…In glioblastoma, the most aggressive brain cancer, a complex microenvironment of heterogeneity and immunosuppression, are considerable hurdles to classify the…”
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Long non-coding RNA HOTAIR promotes glioblastoma cell cycle progression in an EZH2 dependent manner by Zhang, Kailiang, Sun, Xiaotian, Zhou, Xuan, Han, Lei, Chen, Luyue, Shi, Zhendong, Zhang, Anling, Ye, Minhua, Wang, Qixue, Liu, Chaoyong, Wei, Jianwei, Ren, Yu, Yang, Jingxuan, Zhang, Jianning, Pu, Peiyu, Li, Min, Kang, Chunsheng

“…The long non-coding RNA Hox transcript antisense intergenic RNA (HOTAIR) was recently implicated in breast cancer metastasis and is predictive of poor…”
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The role of microglia immunometabolism in neurodegeneration: Focus on molecular determinants and metabolic intermediates of metabolic reprogramming by Wang, Qixue, Lu, Mengna, Zhu, Xinyu, Gu, Xinyi, Zhang, Ting, Xia, Chenyi, Yang, Li, Xu, Ying, Zhou, Mingmei

“…Microglia, resident macrophages that act as the brain’s innate immune cells, play a key role in initiating a defense response to the infection or…”
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Inhibition of ERK1/2 and activation of LXR synergistically reduce atherosclerotic lesions in ApoE-deficient mice by Chen, Yuanli, Duan, Yajun, Yang, Xiaoxiao, Sun, Lei, Liu, Mengyang, Wang, Qixue, Ma, Xingzhe, Zhang, Wenwen, Li, Xiaoju, Hu, Wenquan, Miao, Robert Q, Xiang, Rong, Hajjar, David P, Han, Jihong

“…Activation of liver X receptor (LXR) inhibits atherosclerosis but induces hypertriglyceridemia. In vitro, it has been shown that mitogen-activated protein…”
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Editorial: The State-of-Art in Immuno-Oncology, What to Do With Glioblastoma? by Cui, Xiaoteng, Wang, Qixue, Kang, Chunsheng

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Exosomes: Potential key players towards novel therapeutic options in diabetic wounds by Feng, Jiawei, Yao, Yichen, Wang, Qixue, Han, Xiaozhou, Deng, Xiaofei, Cao, Yemin, Chen, Xinghua, Zhou, Mingmei, Zhao, Cheng

“…Diabetic wounds are usually difficult to heal, and wounds in foot in particular are often aggravated by infection, trauma, diabetic neuropathy, peripheral…”
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Expert opinion on translational research for advanced glioblastoma treatment by Cui, Xiaoteng, Wang, Yunfei, Zhou, Junhu, Wang, Qixue, Kang, Chunsheng

“…Malignant gliomas are known to be one of the most difficult diseases to diagnose and treat because of the infiltrative growth pattern, rapid progression, and…”
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A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep by Li, Yansheng, Ren, Yu, Wang, Yunfei, Tan, Yanli, Wang, Qixue, Cai, Jinquan, Zhou, Junhu, Yang, Chao, Zhao, Kai, Yi, Kaikai, Jin, Weili, Wang, Lin, Liu, Mingyang, Yang, Jingxuan, Li, Min, Kang, Chunsheng

“…Over 20% of cancer 'driver' genes encode chromatin regulators. Long noncoding RNAs (lincRNAs), which are dysregulated in various cancers, play a critical role…”
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Precipitation and plant community-weighted mean traits determine total transpirable soil water in a desert grassland by Chen, Juan, Song, Naiping, Wang, Xing, Meng, Chen, Zhang, Yi, Chen, Lin, Wang, Qixue, Lv, Hao, Wu, Xudong, Yu, Dian

“…•CWM is the main biological factor affecting TTSW variation.•The functional relationship between CWM and TTSW varies across community types.•The selection…”
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The Impact of Instant Coffee and Decaffeinated Coffee on the Gut Microbiota and Depression-Like Behaviors of Sleep-Deprived Rats by Gu, Xinyi, Zhang, Shuyi, Ma, Weini, Wang, Qixue, Li, Ying, Xia, Chenyi, Xu, Ying, Zhang, Ting, Yang, Li, Zhou, Mingmei

“…Based on our previous research, chronic paradoxical sleep deprivation (PSD) can cause depression-like behaviors and microbial changes in gut microbiota…”
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RUNX1/NPM1/H3K4me3 complex contributes to extracellular matrix remodeling via enhancing FOSL2 transcriptional activation in glioblastoma by Cui, Xiaoteng, Huo, Dawei, Wang, Qixue, Wang, Yunfei, Liu, Xiaomin, Zhao, Kai, You, Yongping, Zhang, Junxia, Kang, Chunsheng

“…Extracellular matrix (ECM) remodeling has been implicated in the tumor malignant progression and immune escape in glioblastoma (GBM). Runt-related…”
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Water utilization of typical plant communities in desert steppe, China by Chen, Juan, Wang, Xing, Song, Naiping, Wang, Qixue, Wu, Xudong

“…Water is a limiting factor in the restoration and construction of desert steppe. Exploring plant water sources is necessary to understand soil-plant…”
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Single-Cell Transcriptomics of Glioblastoma Reveals a Unique Tumor Microenvironment and Potential Immunotherapeutic Target Against Tumor-Associated Macrophage by Cui, Xiaoteng, Wang, Qixue, Zhou, Junhu, Wang, Yunfei, Xu, Can, Tong, Fei, Wang, Hongjun, Kang, Chunsheng

“…The main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studies investigating the activation status of TAM in GBM are mainly…”
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Effects of electroacupuncture on urinary metabolome and microbiota in presenilin1/2 conditional double knockout mice by Gao, Jie, Zhou, Nian, Lu, Mengna, Wang, Qixue, Zhao, Chenyi, Wang, Jian, Zhou, Mingmei, Xu, Ying

“…The treatment of Alzheimer's disease (AD) is still a worldwide problem due to the unclear pathogenesis and lack of effective therapeutic targets. In recent…”
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Wounds under diabetic milieu: The role of immune cellar components and signaling pathways by Lin, Siyuan, Wang, Qixue, Huang, Xiaoting, Feng, Jiawei, Wang, Yuqing, Shao, Tengteng, Deng, Xiaofei, Cao, Yemin, Chen, Xinghua, Zhou, Mingmei, Zhao, Cheng

“…A major challenge in the field of diabetic wound healing is to confirm the body's intrinsic mechanism that could sense the immune system damage promptly and…”
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Urinary metabolomic changes and microbiotic alterations in presenilin1/2 conditional double knockout mice by Gao, Jie, Zhou, Nian, Wu, Yongkang, Lu, Mengna, Wang, Qixue, Xia, Chenyi, Zhou, Mingmei, Xu, Ying

“…Background Given the clinical low efficient treatment based on mono-brain-target design in Alzheimer's disease (AD) and an increasing emphasis on…”
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