Search Results - "von der Mark, Elisabeth"

Modulating cholesteryl ester transfer protein activity maintains efficient pre-β-HDL formation and increases reverse cholesterol transport[S] by Niesor, Eric J., Magg, Christine, Ogawa, Naoto, Okamoto, Hiroshi, von der Mark, Elisabeth, Matile, Hugues, Schmid, Georg, Clerc, Roger G., Chaput, Evelyne, Blum-Kaelin, Denise, Huber, Walter, Thoma, Ralf, Pflieger, Philippe, Kakutani, Makoto, Takahashi, Daisuke, Dernick, Gregor, Maugeais, Cyrille

“…The mechanism by which cholesteryl ester transfer protein (CETP) activity affects HDL metabolism was investigated using agents that selectively target CETP…”
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Synthesis and Structure−Activity Studies of Novel Orally Active Non-Terpenoic 2,3-Oxidosqualene Cyclase Inhibitors by Dehmlow, Henrietta, Aebi, Johannes D, Jolidon, Synèse, Ji, Yu-Hua, von der Mark, Elisabeth M, Himber, Jacques, Morand, Olivier H

“…New orally active non-terpenoic inhibitors of human 2,3-oxidosqualene cyclase (hOSC) are reported. The starting point for the optimization process was a set of…”
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Multidimensional profiling of plasma lipoproteins by size exclusion chromatography followed by reverse-phase protein arrays by Dernick, Gregor, Obermüller, Stefan, Mangold, Cyrill, Magg, Christine, Matile, Hugues, Gutmann, Oliver, von der Mark, Elisabeth, Handschin, Corinne, Maugeais, Cyrille, Niesor, Eric J.

“…The composition of lipoproteins and the association of proteins with various particles are of much interest in the context of cardiovascular disease. Here, we…”
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Lipid and apoprotein composition of HDL in partial or complete CETP deficiency by Niesor, Eric J, von der Mark, Elisabeth, Calabresi, Laura, Averna, Maurizio, Cefalù, Angelo B, Tarugi, Patrizia, Nilsson, Peter, Dernick, Gregor

“…Hyperalphalipoproteinemia, as observed in patients who are either homozygous or heterozygous for cholesteryl ester transfer protein (CETP) deficiency, has been…”
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Human Monocyte-Derived Macrophages Express an [nearly =] 120-kD Ox-LDL Binding Protein With Strong Identity to CD68 by van der Kooij, Maaike A, von der Mark, Elisabeth M, Kruijt, J. Kar, van Velzen, Agnes, van Berkel, Theo J.C, Morand, Olivier H

“…A protein that specifically binds oxidized LDL (Ox-LDL) has recently been characterized in mouse peritoneal macrophages and identified as macrosialin, a…”
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Dalcetrapib Does Not Prevent CETP-Induced Pre-β1-HDL Formation, a Potential Marker of HDL Functionality, in Human Plasma In Vitro and in Treated Patients by Niesor, Eric J., PhD, Maugeais, Cyrille, PhD, Dernick, Gregor, PhD, von der Mark, Elisabeth, MSc, Kallend, David, MB, BS

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Oxidosqualene Cyclase (OSC) Inhibitors for the Treatment of Dyslipidemia by Henrietta Dehmlow, Ralf Thoma, Armin Ruf, Narendra Panday, Elisabeth Von Der Mark, Olivier Morand, Hans Peter Märki, Manfred Kansy, Peter Hartman, Philippe Coassolo, Alexander Chucholowski, Denise Blum-Kaelin, Johannes Aebi, Jean Ackermann, Tanja Schulz-Gasch

“…Novel inhibitors of oxidosqualene cyclase (OSC) for the treatment of dyslipidemia are reported. Starting point for the chemistry program was a set of compounds…”
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Evidence for a role of CETP in HDL remodeling and cholesterol efflux: Role of cysteine 13 of CETP by Maugeais, Cyrille, Perez, Anne, von der Mark, Elisabeth, Magg, Christine, Pflieger, Philippe, Niesor, Eric J.

“…Cholesteryl ester transfer protein (CETP), a key regulator of high-density lipoprotein (HDL) metabolism, induces HDL remodeling by transferring lipids between…”
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Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP by Lauer, Matthias E., Graff-Meyer, Alexandra, Rufer, Arne C., Maugeais, Cyrille, von der Mark, Elisabeth, Matile, Hugues, D’Arcy, Brigitte, Magg, Christine, Ringler, Philippe, Müller, Shirley A., Scherer, Sebastian, Dernick, Gregor, Thoma, Ralf, Hennig, Michael, Niesor, Eric J., Stahlberg, Henning

“…The cholesteryl ester transfer protein (CETP) enables the transfer of cholesteryl ester (CE) from high-density lipoproteins (HDL) to low-density lipoproteins…”
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Abstract 69: The Increase in Dalcetrapib-Induced HDL Remodeling Is Dependent on Cysteine 13 of Cholesteryl Ester Transfer Protein and Does Not Involve Phospholipid Transfer Protein by Maugeais, Cyrille, Perez, Anne, von der Mark, Elisabeth, Tetaz, Tim, Schmid, Georg, Niesor, Eric J

“…Abstract only Introduction: Inhibition of the cholesteryl ester transfer between HDL and apoB-containing lipoproteins by dalcetrapib requires cysteine 13 (C13)…”
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Dalcetrapib does not prevent CETP-induced pre-β1-HDL formation, a potential marker of HDL functionality, in human plasma in vitro and in treated patients by Niesor, Eric J, von der Mark, Elisabeth, Dernick, Gregor, Maugeais, Cyrille, Kallend, David

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Different Binding Modes of Compounds Affecting CETP Activity: Dalcetrapib and Torcetrapib by Magg, Christine, Maugeais, Cyrille, Dernick, Gregor, Huber, Walter, von der Mark, Elisabeth, Schmid, Georg, Thoma, Ralf, Niesor, Eric J.

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Dalcetrapib preserves CETP-induced pre-β-HDL formation in vitro , in contrast to torcetrapib and anacetrapib by Magg, Christine, Dernick, Gregor, von der Mark, Elisabeth, Schmid, Georg, Matile, Hugues, Chaput, Evelyne, Blum-Kaelin, Denise, Maugeais, Cyrille, Niesor, Eric J

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