Search Results - "von dem Borne, Peter A."

Autologous haematopoietic stem-cell transplantation versus bortezomib–melphalan–prednisone, with or without bortezomib–lenalidomide–dexamethasone consolidation therapy, and lenalidomide maintenance for newly diagnosed multiple myeloma (EMN02/HO95): a multicentre, randomised, open-label, phase 3 study by Cavo, Michele, Gay, Francesca, Beksac, Meral, Pantani, Lucia, Petrucci, Maria Teresa, Dimopoulos, Meletios A, Dozza, Luca, van der Holt, Bronno, Zweegman, Sonja, Oliva, Stefania, van der Velden, Vincent H J, Zamagni, Elena, Palumbo, Giuseppe A, Patriarca, Francesca, Montefusco, Vittorio, Galli, Monica, Maisnar, Vladimir, Gamberi, Barbara, Hansson, Markus, Belotti, Angelo, Pour, Ludek, Ypma, Paula, Grasso, Mariella, Croockewit, Alexsandra, Ballanti, Stelvio, Offidani, Massimo, Vincelli, Iolanda D, Zambello, Renato, Liberati, Anna Marina, Andersen, Niels Frost, Broijl, Annemiek, Troia, Rossella, Pascarella, Anna, Benevolo, Giulia, Levin, Mark-David, Bos, Gerard, Ludwig, Heinz, Aquino, Sara, Morelli, Anna Maria, Wu, Ka Lung, Boersma, Rinske, Hajek, Roman, Durian, Marc, von dem Borne, Peter A, Caravita di Toritto, Tommaso, Zander, Thilo, Driessen, Christoph, Specchia, Giorgina, Waage, Anders, Gimsing, Peter, Mellqvist, Ulf-Henrik, van Marwijk Kooy, Marinus, Minnema, Monique, Mandigers, Caroline, Cafro, Anna Maria, Palmas, Angelo, Carvalho, Susanna, Spencer, Andrew, Boccadoro, Mario, Sonneveld, Pieter

“…The emergence of highly active novel agents has led some to question the role of autologous haematopoietic stem-cell transplantation (HSCT) and subsequent…”
Get full text

High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations by Hombrink, Pleun, Hadrup, Sine R, Bakker, Arne, Kester, Michel G D, Falkenburg, J H Frederik, von dem Borne, Peter A, Schumacher, Ton N M, Heemskerk, Mirjam H M

“…T-cell recognition of minor histocompatibility antigens (MiHA) plays an important role in the graft-versus-tumor (GVT) effect of allogeneic stem cell…”
Get full text

Higher survival following transplantation with a mismatched unrelated donor with posttransplant cyclophosphamide‐based graft‐versus‐host disease prophylaxis than with double unit umbilical cord blood in patients with acute myeloid leukemia in first complete remission: A study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation by Baron, Frédéric, Labopin, Myriam, Versluis, Jurjen, Vydra, Jan, von dem Borne, Peter A., Nicholson, Emma, Blaise, Didier, Protheroe, Rachel, Kulagin, Alexander, Bulabois, Claude Eric, Rovira, Montserrat, Chevallier, Patrice, Forcade, Edouard, Byrne, Jenny, Sanz, Jaime, Ruggeri, Annalisa, Mohty, Mohamad, Ciceri, Fabio

“…The best donor option for acute myeloid leukemia (AML) patients lacking an HLA‐matched donor has remained intensively debated. We herein report the results of…”
Get full text

Improved diagnosis of viral encephalitis in adult and pediatric hematological patients using viral metagenomics by Carbo, Ellen C., Buddingh, Emilie P., Karelioti, Evita, Sidorov, Igor A., Feltkamp, Mariet C.W., Borne, Peter A. von dem, Verschuuren, Jan J.G.M., Kroes, Aloys C.M., Claas, Eric C.J., de Vries, Jutte J.C.

“…•A metagenomics protocol employing virus capture probes was validated and retrospectively applied to 41 hematological adult and pediatric patients presenting…”
Get full text

Cord blood transplantation for AML: Comparable LFS in patients with de novo versus secondary AML in CR1, an ALWP/EBMT study by Baron, Frédéric, Nagler, Arnon, Galimard, Jacques-Emmanuel, Sanz, Jaime, Versluis, Jurjen, Forcade, Edouard, Chevallier, Patrice, Sirvent, Anne, Anthias, Chloe, Kuball, Jürgen, Furst, Sabine, Rambaldi, Alessandro, Sierra, Jorge, von dem Borne, Peter A, Gallego Hernanz, Maria Pilar, Cluzeau, Thomas, Robinson, Stephen, Raiola, Anna Maria, Labussière-Wallet, Hélène, Byrne, Jenny L, Malfuson, Jean-Valère, Ruggeri, Annalisa, Mohty, Mohamad, Ciceri, Fabio

“…We investigated whether secondary versus de novo acute myeloid leukaemia (AML) would be associated with poor outcomes in adult acute AML patients in first…”
Get full text

Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting by Slomp, Anne, Moesbergen, Laura M., Gong, Jia-nan, Cuenca, Marta, von dem Borne, Peter A., Sonneveld, Pieter, Huang, David C.S., Minnema, Monique C., Peperzak, Victor

“…Prosurvival BCL-2 family proteins are potent inhibitors of apoptosis and often overexpressed in lymphoid malignancies. In multiple myeloma (MM), MCL-1…”
Get full text

The Effect of Graft-Versus-Host Disease on Skin Endothelial and Epithelial Cell Chimerism in Stem-Cell Transplant Recipients by WILLEMZE, Annemieke J, BAKKER, Astrid C, VON DEM BORNE, Peter A, BAJEMA, Ingeborg M, VOSSEN, Jaak M

“…Recent evidence indicates that bone marrow-derived cells contribute to endothelial and epithelial cell renewal in recipients of an allogeneic stem-cell…”
Get full text

Effect of invasive aspergillosis on risk for different causes of death in older patients with acute myeloid leukaemia or high-risk myelodysplastic syndrome by van Grootveld, Rebecca, Masarotto, Valentina, von dem Borne, Peter A, Blijlevens, Nicole M A, Chitu, Dana A, van der Beek, Martha T, Fiocco, Marta, de Boer, Mark G J

“…Study objectives were to estimate the cumulative incidence of death due to different causes of death (CODs) and investigate the effect of invasive…”
Get full text

Compatibility at amino acid position 98 of MICB reduces the incidence of graft-versus-host disease in conjunction with the CMV status by Carapito, Raphael, Aouadi, Ismail, Pichot, Angélique, Spinnhirny, Perrine, Morlon, Aurore, Kotova, Irina, Macquin, Cécile, Rolli, Véronique, Cesbron, Anne, Gagne, Katia, Oudshoorn, Machteld, van der Holt, Bronno, Labalette, Myriam, Spierings, Eric, Picard, Christophe, Loiseau, Pascale, Tamouza, Ryad, Toubert, Antoine, Parissiadis, Anne, Dubois, Valérie, Paillard, Catherine, Maumy-Bertrand, Myriam, Bertrand, Frédéric, von dem Borne, Peter A., Kuball, Jürgen H. E., Michallet, Mauricette, Lioure, Bruno, Peffault de Latour, Régis, Blaise, Didier, Cornelissen, Jan J., Yakoub-Agha, Ibrahim, Claas, Frans, Moreau, Philippe, Charron, Dominique, Mohty, Mohamad, Morishima, Yasuo, Socié, Gérard, Bahram, Seiamak

“…Graft-versus-host disease (GVHD) and cytomegalovirus (CMV)-related complications are leading causes of mortality after unrelated-donor hematopoietic cell…”
Get full text

Risk factors for graft-versus-host-disease after donor lymphocyte infusion following T-cell depleted allogeneic stem cell transplantation by Koster, Eva A S, von dem Borne, Peter A, van Balen, Peter, Marijt, Erik W A, Tjon, Jennifer M L, Snijders, Tjeerd J F, van Lammeren, Daniëlle, Veelken, Hendrik, Falkenburg, J H Frederik, Halkes, Constantijn J M, de Wreede, Liesbeth C

“…Unmodified donor lymphocyte infusions (DLI) after allogeneic stem cell transplantation (alloSCT) can boost the beneficial Graft-versus-Leukemia (GvL) effect…”
Get full text

Thrombocytopenia and the effect of platelet transfusions on the occurrence of intracranial hemorrhage in patients with acute leukemia – a nested case-control study by Cornelissen, Loes L., Kreuger, Aukje L., Caram-Deelder, Camila, Middelburg, Rutger A., Kerkhoffs, Jean Louis H., von dem Borne, Peter A., Beckers, Erik A. M., de Vooght, Karen M. K., Kuball, Jürgen, Zwaginga, J. J., van der Bom, Johanna G.

“…We designed a study to describe the incidence of intracranial hemorrhage according to severity and duration of thrombocytopenia and to quantify the…”
Get full text

Multi-state analysis illustrates treatment success after stem cell transplantation for acute myeloid leukemia followed by donor lymphocyte infusion by Eefting, Matthias, de Wreede, Liesbeth C, Halkes, Constantijn J M, von dem Borne, Peter A, Kersting, Sabina, Marijt, Erik W A, Veelken, Hendrik, Putter, Hein, Schetelig, Johannes, Falkenburg, J H Frederik

“…In the field of hematopoietic stem cell transplantation, the common approach is to focus outcome analyses on time to relapse and death, without assessing the…”
Get full text

Association between cardiovascular risk factors and intracranial hemorrhage in patients with acute leukemia by Cornelissen, Loes L., Kreuger, Aukje L., Caram‐Deelder, Camila, Huisman, Menno V., Middelburg, Rutger A., Kerkhoffs, Jean Louis H., von dem Borne, Peter A., Beckers, Erik A. M., de Vooght, Karen M. K., Kuball, Jürgen, van der Bom, Johanna G., Zwaginga, Jaap Jan

“…Background Intracranial hemorrhage is seen more frequently in acute leukemia patients compared to the general population. Besides leukemia‐related risk…”
Get full text

Joint models quantify associations between immune cell kinetics and allo-immunological events after allogeneic stem cell transplantation and subsequent donor lymphocyte infusion by Koster, Eva A. S., Bonneville, Edouard F., Borne, Peter A. von dem, van Balen, Peter, Marijt, Erik W. A., Tjon, Jennifer M. L., Snijders, Tjeerd J. F., van Lammeren, Daniëlle, Veelken, Hendrik, Putter, Hein, Falkenburg, J. H. Frederik, Halkes, Constantijn J. M., de Wreede, Liesbeth C.

“…Alloreactive donor-derived T-cells play a pivotal role in alloimmune responses after allogeneic hematopoietic stem cell transplantation (alloSCT); both in the…”
Get full text

Oral bacteria and yeasts in relationship to oral ulcerations in hematopoietic stem cell transplant recipients by Laheij, Alexa M. G. A., de Soet, Johannes J., von dem Borne, Peter A., Kuijper, Ed J., Kraneveld, Eefje A., van Loveren, Cor, Raber-Durlacher, Judith E.

“…Background Oral mucositis is a serious and debilitating side effect of conditioning regimens for hematopoietic stem cell transplant (HSCT). Through HSCT, the…”
Get full text

High Mutation Frequency of the PIGA Gene in T Cells Results in Reconstitution of GPI Anchor - /CD52 - T Cells That Can Give Early Immune Protection after Alemtuzumab-Based T Cell-Depleted Allogeneic Stem Cell Transplantation by Loeff, Floris C, Falkenburg, J H Frederik, Hageman, Lois, Huisman, Wesley, Veld, Sabrina A J, van Egmond, H M Esther, van de Meent, Marian, von dem Borne, Peter A, Veelken, Hendrik, Halkes, Constantijn J M, Jedema, Inge

“…Alemtuzumab (ALM) is used for T cell depletion in the context of allogeneic hematopoietic stem cell transplantation (alloSCT) to prevent acute…”
Get full text

Distribution and clinical determinants of time‐to‐positivity of blood cultures in patients with neutropenia by Lambregts, Merel M.C., Warreman, Eva B., Bernards, Alexandra T., Veelken, Hendrik, von dem Borne, Peter A., Dekkers, Olaf M., Visser, Leo G., de Boer, Mark G.

“…Objectives Blood cultures (BCs) are essential in the evaluation of neutropenic fever. Modern BC systems have significantly reduced the time‐to‐positivity (TTP)…”
Get full text

Exploratory Study of Predicted Indirectly ReCognizable HLA Epitopes in Mismatched Hematopoietic Cell Transplantations by Geneugelijk, Kirsten, Thus, Kirsten A, van Deutekom, Hanneke W M, Calis, Jorg J A, Borst, Eric, Keşmir, Can, Oudshoorn, Machteld, van der Holt, Bronno, Meijer, Ellen, Zeerleder, Sacha, de Groot, Marco R, von dem Borne, Peter A, Schaap, Nicolaas, Cornelissen, Jan, Kuball, Jürgen, Spierings, Eric

“…HLA-mismatches in hematopoietic stem-cell transplantation are associated with an impaired overall survival (OS). The aim of this study is to explore whether…”
Get full text

The diagnosis and treatment of invasive aspergillosis in Dutch haematology units facing a rapidly increasing prevalence of azole‐resistance. A nationwide survey and rationale for the DB‐MSG 002 study protocol by Schauwvlieghe, Alexander F. A. D., Jonge, Nick, Dijk, Karin, Verweij, Paul E., Brüggemann, Roger J., Biemond, Bart J., Bart, Aldert, von dem Borne, Peter A., Verbon, Annelies, Beek, Martha T., Demandt, Astrid M. P., Oudhuis, Guy J., Cornelissen, Jan J., Velden, Walter J. F. M., Span, Lambert F. R., Kampinga, Greetje A., Bruns, Anke H., Vonk, Alieke G., Haas, Pieter–Jan A., Doorduijn, Jeanette K., Rijnders, Bart J. A.

“…Summary Patients with haematological malignancies are at risk for invasive fungal diseases (IFD). A survey was conducted in all Dutch academic haematology…”
Get full text

Rhinovirus viremia in adult patients with high viral load in bronchoalveolar lavages by Van Rijn, Anneloes L., Claas, Eric C., von dem Borne, Peter A., Kroes, Aloys C.M., de Vries, Jutte J.C.

“…•Demonstrates rhinovirus viremia in adults.•The percentage (15%) of viremia in these highly immunocompromised adults is low.•Rhinovirus A01, A24, B52 and B92…”
Get full text